Reactome Pathway Database
Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Reactome Pathway Database
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
Schema
>
SimpleEntity
>
Entries
2MACA-CoA [mitochondrial matrix]
Show undefined attributes
Go to Details
compartment
[Compartment:5460] mitochondrial matrix
consumedByEvent
[FailedReaction:R-HSA-9915356] ACAT1 mutants don't synthesize propionyl-CoA or acetyl-CoA - Homo sapiens
[Reaction:R-PFA-70844] alpha-methylacetoacetyl-CoA + CoA => propionyl-CoA + acetyl-CoA - Plasmodium falciparum
[Reaction:R-DDI-70844] alpha-methylacetoacetyl-CoA + CoA => propionyl-CoA + acetyl-CoA - Dictyostelium discoideum
[Reaction:R-CEL-70844] alpha-methylacetoacetyl-CoA + CoA => propionyl-CoA + acetyl-CoA - Caenorhabditis elegans
[Reaction:R-DME-70844] alpha-methylacetoacetyl-CoA + CoA => propionyl-CoA + acetyl-CoA - Drosophila melanogaster
[Reaction:R-GGA-70844] alpha-methylacetoacetyl-CoA + CoA => propionyl-CoA + acetyl-CoA - Gallus gallus
[Reaction:R-XTR-70844] alpha-methylacetoacetyl-CoA + CoA => propionyl-CoA + acetyl-CoA - Xenopus tropicalis
[Reaction:R-SSC-70844] alpha-methylacetoacetyl-CoA + CoA => propionyl-CoA + acetyl-CoA - Sus scrofa
[Reaction:R-BTA-70844] alpha-methylacetoacetyl-CoA + CoA => propionyl-CoA + acetyl-CoA - Bos taurus
[Reaction:R-CFA-70844] alpha-methylacetoacetyl-CoA + CoA => propionyl-CoA + acetyl-CoA - Canis familiaris
[Reaction:R-RNO-70844] alpha-methylacetoacetyl-CoA + CoA => propionyl-CoA + acetyl-CoA - Rattus norvegicus
[Reaction:R-MMU-70844] alpha-methylacetoacetyl-CoA + CoA => propionyl-CoA + acetyl-CoA - Mus musculus
[Reaction:R-HSA-70844] alpha-methylacetoacetyl-CoA + CoA => propionyl-CoA + acetyl-CoA - Homo sapiens
[Reaction:R-DDI-508369] alpha-methylacetoacetyl-CoA + NADH + H+ <=> alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ - Dictyostelium discoideum
[Reaction:R-CEL-508369] alpha-methylacetoacetyl-CoA + NADH + H+ <=> alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ - Caenorhabditis elegans
[Reaction:R-DME-508369] alpha-methylacetoacetyl-CoA + NADH + H+ <=> alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ - Drosophila melanogaster
[Reaction:R-GGA-508369] alpha-methylacetoacetyl-CoA + NADH + H+ <=> alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ - Gallus gallus
[Reaction:R-XTR-508369] alpha-methylacetoacetyl-CoA + NADH + H+ <=> alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ - Xenopus tropicalis
[Reaction:R-DRE-508369] alpha-methylacetoacetyl-CoA + NADH + H+ <=> alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ - Danio rerio
[Reaction:R-SSC-508369] alpha-methylacetoacetyl-CoA + NADH + H+ <=> alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ - Sus scrofa
[Reaction:R-BTA-508369] alpha-methylacetoacetyl-CoA + NADH + H+ <=> alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ - Bos taurus
[Reaction:R-CFA-508369] alpha-methylacetoacetyl-CoA + NADH + H+ <=> alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ - Canis familiaris
[Reaction:R-RNO-508369] alpha-methylacetoacetyl-CoA + NADH + H+ <=> alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ - Rattus norvegicus
[Reaction:R-MMU-508369] alpha-methylacetoacetyl-CoA + NADH + H+ <=> alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ - Mus musculus
[Reaction:R-HSA-508369] alpha-methylacetoacetyl-CoA + NADH + H+ <=> alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ - Homo sapiens
[Reaction:R-DRE-70844] alpha-methylacetoacetyl-CoA + CoA => propionyl-CoA + acetyl-CoA - Danio rerio
crossReference
[DatabaseIdentifier:34500] COMPOUND:C03344
dbId
70836
displayName
2MACA-CoA [mitochondrial matrix]
inDisease
false
maxDepth
1
modified
[InstanceEdit:9917131] Stephan, Ralf, 2024年07月30日
name
2MACA-CoA
alpha-methylacetoacetyl-CoA
2-methylacetoacetyl-CoA
producedByEvent
[Reaction:R-DDI-70837] alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ <=> alpha-methylacetoacetyl-CoA + NADH + H+ - Dictyostelium discoideum
[Reaction:R-CEL-70837] alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ <=> alpha-methylacetoacetyl-CoA + NADH + H+ - Caenorhabditis elegans
[Reaction:R-DME-70837] alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ <=> alpha-methylacetoacetyl-CoA + NADH + H+ - Drosophila melanogaster
[Reaction:R-GGA-70837] alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ <=> alpha-methylacetoacetyl-CoA + NADH + H+ - Gallus gallus
[Reaction:R-XTR-70837] alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ <=> alpha-methylacetoacetyl-CoA + NADH + H+ - Xenopus tropicalis
[Reaction:R-SSC-70837] alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ <=> alpha-methylacetoacetyl-CoA + NADH + H+ - Sus scrofa
[Reaction:R-BTA-70837] alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ <=> alpha-methylacetoacetyl-CoA + NADH + H+ - Bos taurus
[Reaction:R-CFA-70837] alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ <=> alpha-methylacetoacetyl-CoA + NADH + H+ - Canis familiaris
[Reaction:R-RNO-70837] alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ <=> alpha-methylacetoacetyl-CoA + NADH + H+ - Rattus norvegicus
[Reaction:R-MMU-70837] alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ <=> alpha-methylacetoacetyl-CoA + NADH + H+ - Mus musculus
[Reaction:R-HSA-70837] alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ <=> alpha-methylacetoacetyl-CoA + NADH + H+ - Homo sapiens
[Reaction:R-DRE-70837] alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ <=> alpha-methylacetoacetyl-CoA + NADH + H+ - Danio rerio
referenceEntity
[ReferenceMolecule:chebi:57335] 2-methylacetoacetyl-CoA(4-) [ChEBI:57335]
referenceType
ReferenceMolecule
schemaClass
SimpleEntity
stId
R-ALL-70836
updateTrackers
[UpdateTracker:9919549] Update Tracker - [SimpleEntity:70836] 2MACA-CoA [mitochondrial matrix] - v90:[add_removeReferenceEntity]
[UpdateTracker:9892805] Update Tracker - [SimpleEntity:70836] 2MACA-CoA [mitochondrial matrix] - v54:[addName]
Referrals
(updatedInstance)
[UpdateTracker:9919549] Update Tracker - [SimpleEntity:70836] 2MACA-CoA [mitochondrial matrix] - v90:[add_removeReferenceEntity]
[UpdateTracker:9892805] Update Tracker - [SimpleEntity:70836] 2MACA-CoA [mitochondrial matrix] - v54:[addName]
(input)
[FailedReaction:R-HSA-9915356] ACAT1 mutants don't synthesize propionyl-CoA or acetyl-CoA
[Reaction:R-PFA-70844] alpha-methylacetoacetyl-CoA + CoA => propionyl-CoA + acetyl-CoA
[Reaction:R-DDI-70844] alpha-methylacetoacetyl-CoA + CoA => propionyl-CoA + acetyl-CoA
[Reaction:R-CEL-70844] alpha-methylacetoacetyl-CoA + CoA => propionyl-CoA + acetyl-CoA
[Reaction:R-DME-70844] alpha-methylacetoacetyl-CoA + CoA => propionyl-CoA + acetyl-CoA
[Reaction:R-GGA-70844] alpha-methylacetoacetyl-CoA + CoA => propionyl-CoA + acetyl-CoA
[Reaction:R-XTR-70844] alpha-methylacetoacetyl-CoA + CoA => propionyl-CoA + acetyl-CoA
[Reaction:R-SSC-70844] alpha-methylacetoacetyl-CoA + CoA => propionyl-CoA + acetyl-CoA
[Reaction:R-BTA-70844] alpha-methylacetoacetyl-CoA + CoA => propionyl-CoA + acetyl-CoA
[Reaction:R-CFA-70844] alpha-methylacetoacetyl-CoA + CoA => propionyl-CoA + acetyl-CoA
[Reaction:R-RNO-70844] alpha-methylacetoacetyl-CoA + CoA => propionyl-CoA + acetyl-CoA
[Reaction:R-MMU-70844] alpha-methylacetoacetyl-CoA + CoA => propionyl-CoA + acetyl-CoA
[Reaction:R-HSA-70844] alpha-methylacetoacetyl-CoA + CoA => propionyl-CoA + acetyl-CoA
[Reaction:R-DDI-508369] alpha-methylacetoacetyl-CoA + NADH + H+ <=> alpha-methyl-beta-hydroxybutyryl-CoA + NAD+
[Reaction:R-CEL-508369] alpha-methylacetoacetyl-CoA + NADH + H+ <=> alpha-methyl-beta-hydroxybutyryl-CoA + NAD+
[Reaction:R-DME-508369] alpha-methylacetoacetyl-CoA + NADH + H+ <=> alpha-methyl-beta-hydroxybutyryl-CoA + NAD+
[Reaction:R-GGA-508369] alpha-methylacetoacetyl-CoA + NADH + H+ <=> alpha-methyl-beta-hydroxybutyryl-CoA + NAD+
[Reaction:R-XTR-508369] alpha-methylacetoacetyl-CoA + NADH + H+ <=> alpha-methyl-beta-hydroxybutyryl-CoA + NAD+
[Reaction:R-DRE-508369] alpha-methylacetoacetyl-CoA + NADH + H+ <=> alpha-methyl-beta-hydroxybutyryl-CoA + NAD+
[Reaction:R-SSC-508369] alpha-methylacetoacetyl-CoA + NADH + H+ <=> alpha-methyl-beta-hydroxybutyryl-CoA + NAD+
[Reaction:R-BTA-508369] alpha-methylacetoacetyl-CoA + NADH + H+ <=> alpha-methyl-beta-hydroxybutyryl-CoA + NAD+
[Reaction:R-CFA-508369] alpha-methylacetoacetyl-CoA + NADH + H+ <=> alpha-methyl-beta-hydroxybutyryl-CoA + NAD+
[Reaction:R-RNO-508369] alpha-methylacetoacetyl-CoA + NADH + H+ <=> alpha-methyl-beta-hydroxybutyryl-CoA + NAD+
[Reaction:R-MMU-508369] alpha-methylacetoacetyl-CoA + NADH + H+ <=> alpha-methyl-beta-hydroxybutyryl-CoA + NAD+
[Reaction:R-HSA-508369] alpha-methylacetoacetyl-CoA + NADH + H+ <=> alpha-methyl-beta-hydroxybutyryl-CoA + NAD+
[Reaction:R-DRE-70844] alpha-methylacetoacetyl-CoA + CoA => propionyl-CoA + acetyl-CoA
(output)
[Reaction:R-DDI-70837] alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ <=> alpha-methylacetoacetyl-CoA + NADH + H+
[Reaction:R-CEL-70837] alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ <=> alpha-methylacetoacetyl-CoA + NADH + H+
[Reaction:R-DME-70837] alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ <=> alpha-methylacetoacetyl-CoA + NADH + H+
[Reaction:R-GGA-70837] alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ <=> alpha-methylacetoacetyl-CoA + NADH + H+
[Reaction:R-XTR-70837] alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ <=> alpha-methylacetoacetyl-CoA + NADH + H+
[Reaction:R-SSC-70837] alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ <=> alpha-methylacetoacetyl-CoA + NADH + H+
[Reaction:R-BTA-70837] alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ <=> alpha-methylacetoacetyl-CoA + NADH + H+
[Reaction:R-CFA-70837] alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ <=> alpha-methylacetoacetyl-CoA + NADH + H+
[Reaction:R-RNO-70837] alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ <=> alpha-methylacetoacetyl-CoA + NADH + H+
[Reaction:R-MMU-70837] alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ <=> alpha-methylacetoacetyl-CoA + NADH + H+
[Reaction:R-HSA-70837] alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ <=> alpha-methylacetoacetyl-CoA + NADH + H+
[Reaction:R-DRE-70837] alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ <=> alpha-methylacetoacetyl-CoA + NADH + H+
© 2025
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text
Download
Close
AltStyle
によって変換されたページ
(->オリジナル)
/
アドレス:
モード:
デフォルト
音声ブラウザ
ルビ付き
配色反転
文字拡大
モバイル