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Schema
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Entries
44 on 2013年03月31日
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dbId
9787518
displayName
44 on 2013年03月31日
releaseDate
2013年03月31日
releaseNumber
44
schemaClass
Release
Referrals
(release)
[UpdateTracker:9787702] Update Tracker - [BlackBoxEvent:211715] Proteasome mediated degradation of PAK-2p34 - v44:[add_removeInput]
[UpdateTracker:9787991] Update Tracker - [Reaction:947591] P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane - v44:[add_removeInput, add_removeOutput, modifyText]
[UpdateTracker:9787686] Update Tracker - [Pathway:176409] APC/C:Cdc20 mediated degradation of mitotic proteins - v44:[updateIndirectRLE]
[UpdateTracker:9787701] Update Tracker - [Reaction:416320] Trafficking of GluR1-containing AMPA receptors - v44:[add_removeInput, add_removeOutput]
[UpdateTracker:9787957] Update Tracker - [Reaction:71010] MUT isomerises L-MM-CoA to SUCC-CoA - v44:[addInput, addOutput, add_removeLiteratureReference, modifyText]
[UpdateTracker:9788109] Update Tracker - [Pathway:2555396] Mitotic Metaphase and Anaphase - v44:[updateContainedPathway]
[UpdateTracker:9787676] Update Tracker - [Pathway:1489509] DAG and IP3 signaling - v44:[updateIndirectRLE]
[UpdateTracker:9787574] Update Tracker - [Reaction:964962] 2xPDKX:2xZn2+ phosphorylates PDX - v44:[modifyText]
[UpdateTracker:9787552] Update Tracker - [Reaction:182243] Formation of MHC I:Nef Complex - v44:[add_removeInput]
[UpdateTracker:9787546] Update Tracker - [Reaction:372505] Acetylcholine synaptic vesicle docking and priming - v44:[add_removeInput]
[UpdateTracker:9787945] Update Tracker - [BlackBoxEvent:265166] Exocytosis of Insulin - v44:[add_removeInput, add_removeOutput]
[UpdateTracker:9787777] Update Tracker - [BlackBoxEvent:381283] Expression of PPARG - v44:[add_removeOutput, add_removeRegulator]
[UpdateTracker:9788009] Update Tracker - [Reaction:139908] Phosphorylation of DLC2 by MAPK8 - v44:[add_removeOutput, modifyText]
[UpdateTracker:9787681] Update Tracker - [Reaction:165028] Release of the HIV mRNA and Crm1 from Rev in the cytoplasm - v44:[add_removeOutput]
[UpdateTracker:9787952] Update Tracker - [Pathway:76002] Platelet activation, signaling and aggregation - v44:[updateIndirectRLE]
[UpdateTracker:9787656] Update Tracker - [Pathway:111996] Ca-dependent events - v44:[updateIndirectRLE]
[UpdateTracker:9787822] Update Tracker - [Pathway:174495] Synthesis And Processing Of GAG, GAGPOL Polyproteins - v44:[updateContainedRLE, updateIndirectRLE]
[UpdateTracker:9787523] Update Tracker - [Reaction:196773] COASY phosphorylates DP-CoA - v44:[modifyText]
[UpdateTracker:9787637] Update Tracker - [Pathway:109704] PI3K Cascade - v44:[updateContainedRLE]
[UpdateTracker:9788077] Update Tracker - [Pathway:165054] Rev-mediated nuclear export of HIV RNA - v44:[updateContainedRLE]
[UpdateTracker:9787768] Update Tracker - [Reaction:1067667] IL6 binds IL6R - v44:[add_removeInput]
[UpdateTracker:9787995] Update Tracker - [Pathway:399997] Acetylcholine regulates insulin secretion - v44:[updateContainedRLE]
[UpdateTracker:9787850] Update Tracker - [Pathway:168249] Innate Immune System - v44:[addHasEvent, updateIndirectRLE]
[UpdateTracker:9788102] Update Tracker - [Reaction:373342] CX3CR1 binds CX3CL1 - v44:[add_removeInput]
[UpdateTracker:9787816] Update Tracker - [Reaction:380574] Dopamine synaptic vesicle docking and priming - v44:[add_removeInput]
[UpdateTracker:9787841] Update Tracker - [Reaction:167234] Association of Tat with P-TEFb(Cyclin T1:Cdk9) - v44:[add_removeInput]
[UpdateTracker:9787900] Update Tracker - [Reaction:170975] p-FRS2 binds CRKL - v44:[add_removeInput]
[UpdateTracker:9787872] Update Tracker - [Pathway:110478] Insulin signaling pathway - v44:[updateContainedRLE]
[UpdateTracker:9787922] Update Tracker - [BlackBoxEvent:211466] HNF1A-dependent synthesis of HNF4A - v44:[add_removeRegulator]
[UpdateTracker:9787687] Update Tracker - [BlackBoxEvent:211482] HNF1A-dependent synthesis of FOXA3 - v44:[add_removeRegulator]
[UpdateTracker:9787843] Update Tracker - [Pathway:111461] Cytochrome c-mediated apoptotic response - v44:[updateIndirectRLE]
[UpdateTracker:9788110] Update Tracker - [Reaction:380905] Serotonin loaded synaptic vesicle docking and priming - v44:[add_removeInput]
[UpdateTracker:9787555] Update Tracker - [Reaction:189423] PPO oxidises PPGEN9 to PRIN9 - v44:[modifyText]
[UpdateTracker:9788028] Update Tracker - [Pathway:204998] Cell death signalling via NRAGE, NRIF and NADE - v44:[updateIndirectRLE]
[UpdateTracker:9788104] Update Tracker - [Pathway:196849] Metabolism of water-soluble vitamins and cofactors - v44:[updateContainedPathway, updateIndirectRLE]
[UpdateTracker:9787685] Update Tracker - [Reaction:189421] CPO transforms COPRO3 to PPGEN9 - v44:[modifyText]
[UpdateTracker:9787710] Update Tracker - [Reaction:180606] Association of Vpu with CD4 - v44:[add_removeInput]
[UpdateTracker:9787765] Update Tracker - [Pathway:1980143] Signaling by NOTCH1 - v44:[updateIndirectRLE]
[UpdateTracker:9788024] Update Tracker - [Reaction:200908] Nef Binds and activates the Src-family tyrosine kinase Fyn - v44:[add_removeInput]
[UpdateTracker:9787921] Update Tracker - [Pathway:140534] Caspase activation via Death Receptors in the presence of ligand - v44:[addLiteratureReference, modifyText, updateContainedPathway, updateContainedRLE, updateIndirectRLE]
[UpdateTracker:9787771] Update Tracker - [Pathway:392499] Metabolism of proteins - v44:[add_removeHasEvent]
[UpdateTracker:9787999] Update Tracker - [BlackBoxEvent:1980067] NOTCH1 stimulates MYC transcription - v44:[modifyText]
[UpdateTracker:9787847] Update Tracker - [Pathway:162587] HIV Life Cycle - v44:[updateContainedPathway, updateIndirectRLE]
[UpdateTracker:9788023] Update Tracker - [Pathway:400451] Free fatty acids regulate insulin secretion - v44:[updateIndirectRLE]
[UpdateTracker:9788113] Update Tracker - [Pathway:110362] POLB-Dependent Long Patch Base Excision Repair - v44:[updateIndirectRLE]
[UpdateTracker:9787886] Update Tracker - [Pathway:399721] Glutamate binding, activation of AMPA receptors and synaptic plasticity - v44:[updateIndirectRLE]
[UpdateTracker:9787745] Update Tracker - [Pathway:174490] Membrane binding and targetting of GAG proteins - v44:[updateContainedRLE]
[UpdateTracker:9788093] Update Tracker - [Pathway:447041] CHL1 interactions - v44:[updateContainedRLE]
[UpdateTracker:9787878] Update Tracker - [Pathway:1502540] Signaling by Activin - v44:[updateContainedRLE]
[UpdateTracker:9787774] Update Tracker - [Pathway:111453] BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 members - v44:[updateContainedRLE]
[UpdateTracker:9787869] Update Tracker - [Reaction:168896] Binding of NS1 to PKR - v44:[addLiteratureReference, modifyText]
[UpdateTracker:9787825] Update Tracker - [Reaction:184269] Monoubiquitinated N-myristoyl GAG polyprotein is targeted to the late endosomal vesicle membrane by the ESCRT-I complex - v44:[addCatalystActivity, add_removeInput, add_removeOutput]
[UpdateTracker:9788036] Update Tracker - [Reaction:190141] ALAD binds to Pb2+ - v44:[modifyText]
[UpdateTracker:9787551] Update Tracker - [Reaction:164506] Gap repair completes provirus integration - v44:[add_removeOutput]
[UpdateTracker:9787566] Update Tracker - [Pathway:432722] Golgi Associated Vesicle Biogenesis - v44:[updateContainedRLE]
[UpdateTracker:9787683] Update Tracker - [Pathway:2122948] Activated NOTCH1 Transmits Signal to the Nucleus - v44:[updateContainedRLE]
[UpdateTracker:9787910] Update Tracker - [Reaction:937311] ATP12A:ATP4B exchanges K+ for H+ - v44:[modifyText]
[UpdateTracker:9787937] Update Tracker - [Reaction:110459] PIP3 dephosphorylated to PIP2 by DPTEN - v44:[add_removeOutput]
[UpdateTracker:9788084] Update Tracker - [Pathway:388396] GPCR downstream signalling - v44:[updateIndirectRLE]
[UpdateTracker:9787821] Update Tracker - [Reaction:199206] SLC5A6 cotransports extracellular PanK and 2Na+ to cytosol - v44:[modifyText]
[UpdateTracker:9787795] Update Tracker - [Reaction:139893] Granzyme-B activates BID by cleavage - v44:[modifyText]
[UpdateTracker:9787933] Update Tracker - [Pathway:186712] Regulation of beta-cell development - v44:[updateIndirectRLE]
[UpdateTracker:9787638] Update Tracker - [Pathway:399955] SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion - v44:[updateContainedRLE]
[UpdateTracker:9787889] Update Tracker - [Reaction:189465] FECH binds Fe2+ to PRIN9 to form heme - v44:[modifyText]
[UpdateTracker:9787757] Update Tracker - [Pathway:187015] Activation of TRKA receptors - v44:[updateIndirectRLE]
[UpdateTracker:9787898] Update Tracker - [Pathway:397795] G-protein beta:gamma signalling - v44:[updateIndirectRLE]
[UpdateTracker:9787659] Update Tracker - [Reaction:114264] Translocation of activated BAX to the mitochondria - v44:[addLiteratureReference, modifyText]
[UpdateTracker:9788011] Update Tracker - [Pathway:881907] Gastrin-CREB signalling pathway via PKC and MAPK - v44:[updateIndirectRLE]
[UpdateTracker:9787803] Update Tracker - [Reaction:965079] 2xPNPO:2xFMN oxidizes PXAP to PXLP - v44:[modifyText]
[UpdateTracker:9787970] Update Tracker - [Pathway:198933] Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell - v44:[updateContainedRLE]
[UpdateTracker:9787806] Update Tracker - [Reaction:165680] Formation of active mTORC1 complex - v44:[add_removeInput]
[UpdateTracker:9788074] Update Tracker - [Reaction:194800] botE LC cleaves target cell SNAP25 - v44:[add_removeInput, add_removeOutput]
[UpdateTracker:9788056] Update Tracker - [Pathway:193648] NRAGE signals death through JNK - v44:[updateContainedRLE]
[UpdateTracker:9788042] Update Tracker - [Reaction:398184] LARG activation by G alpha 12/13 - v44:[add_removeInput]
[UpdateTracker:9787646] Update Tracker - [Pathway:194306] Neurophilin interactions with VEGF and VEGFR - v44:[updateContainedRLE]
[UpdateTracker:9787811] Update Tracker - [Reaction:216043] Collagen type II binds integrin alpha10beta1 - v44:[add_removeInput]
[UpdateTracker:9787598] Update Tracker - [Pathway:556833] Metabolism of lipids - v44:[addHasEvent, updateContainedPathway]
[UpdateTracker:9787729] Update Tracker - [Pathway:198725] Nuclear Events (kinase and transcription factor activation) - v44:[updateIndirectRLE]
[UpdateTracker:9787830] Update Tracker - [Pathway:156580] Phase II - Conjugation of compounds - v44:[updateIndirectRLE]
[UpdateTracker:9787814] Update Tracker - [BlackBoxEvent:1980078] NOTCH1 stimulates HES5 transcription - v44:[modifyText]
[UpdateTracker:9787690] Update Tracker - [Reaction:2176396] SMURF1 ubiquitinates Smad7 and phosphorylated TGFBR1 - v44:[add_removeOutput]
[UpdateTracker:9787604] Update Tracker - [Reaction:114689] PLC gamma 2-mediated PIP2 hydrolysis - v44:[add_removeInput]
[UpdateTracker:9787763] Update Tracker - [Reaction:194793] botC LC cleaves target cell SNAP25 - v44:[add_removeInput, add_removeOutput]
[UpdateTracker:9788081] Update Tracker - [Pathway:193634] Axonal growth inhibition (RHOA activation) - v44:[updateContainedRLE]
[UpdateTracker:9788052] Update Tracker - [BlackBoxEvent:210784] HNF1B-dependent synthesis of HNF6 protein - v44:[add_removeRegulator]
[UpdateTracker:9787590] Update Tracker - [BlackBoxEvent:400500] Synthesis of prepro-Glucose-dependent Insulinotropic Polypeptide (preproGIP) in intestinal K cells - v44:[add_removeRegulator]
[UpdateTracker:9787668] Update Tracker - [Pathway:111452] Activation and oligomerization of BAK protein - v44:[updateContainedRLE]
[UpdateTracker:9787726] Update Tracker - [Pathway:418990] Adherens junctions interactions - v44:[updateIndirectRLE]
[UpdateTracker:9787834] Update Tracker - [Reaction:196026] Dab2 is recruited to the junctional plaques - v44:[add_removeInput]
[UpdateTracker:9787727] Update Tracker - [BlackBoxEvent:184323] Monoubiquitination of N-myristoyl GAG polyprotein - v44:[add_removeInput, add_removeOutput]
[UpdateTracker:9787550] Update Tracker - [Reaction:622387] PIP2 hydrolysis - v44:[add_removeInput]
[UpdateTracker:9787650] Update Tracker - [Pathway:1369062] ABC transporters in lipid homeostasis - v44:[updateContainedRLE]
[UpdateTracker:9787844] Update Tracker - [Reaction:178178] PP1 dephosphorylates TGFBR1 - v44:[add_removeOutput]
[UpdateTracker:9787693] Update Tracker - [Reaction:1912385] Phosphorylated NICD1 binds FBXW7 - v44:[addLiteratureReference]
[UpdateTracker:9787731] Update Tracker - [Reaction:198609] AKT phosphorylates TSC2, inhibiting it - v44:[add_removeInput]
[UpdateTracker:9787966] Update Tracker - [Reaction:198824] CYB5R3:FAD reduces CYB5A:ferriheme to CYB5A:heme - v44:[modifyText]
[UpdateTracker:9787618] Update Tracker - [BlackBoxEvent:2129353] Tropoelastin associates with microfibrils - v44:[modifyText]
[UpdateTracker:9787519] Update Tracker - [Reaction:2197556] Gamma-secretase complex cleaves mNEXT2 - v44:[modifyText]
[UpdateTracker:9787592] Update Tracker - [Pathway:2468052] Establishment of Sister Chromatid Cohesion - v44:[modifyText, updateContainedRLE]
[UpdateTracker:9787796] Update Tracker - [BlackBoxEvent:265177] Exocyst complex formation - v44:[add_removeInput]
[UpdateTracker:9787520] Update Tracker - [Pathway:199220] Vitamin B5 (pantothenate) metabolism - v44:[updateContainedRLE, updateIndirectRLE]
[UpdateTracker:9787533] Update Tracker - [Pathway:167200] Formation of HIV-1 elongation complex containing HIV-1 Tat - v44:[updateContainedRLE]
[UpdateTracker:9787880] Update Tracker - [Reaction:199014] CD96 binds PVR - v44:[add_removeInput]
[UpdateTracker:9788012] Update Tracker - [Pathway:1234158] Regulation of gene expression by Hypoxia-inducible Factor - v44:[updateContainedRLE]
[UpdateTracker:9787744] Update Tracker - [Reaction:2167917] SMAD7 binds to SMURF1 - v44:[add_removeInput]
[UpdateTracker:9787747] Update Tracker - [BlackBoxEvent:202534] Ubiquitination of NEMO by TRAF6 - v44:[modifyText]
[UpdateTracker:9788053] Update Tracker - [Pathway:1980145] Signaling by NOTCH2 - v44:[addLiteratureReference, add_removeHasEvent, modifyText]
[UpdateTracker:9787639] Update Tracker - [Pathway:373753] Nephrin family interactions - v44:[updateContainedRLE]
[UpdateTracker:9787986] Update Tracker - [Reaction:964970] 2xPDXK:2xZn2+ phosphorylates PXL - v44:[modifyText]
[UpdateTracker:9787675] Update Tracker - [Reaction:2396561] Recruitment of GADS:SLP-76 to p-5Y-LAT - v44:[add_removeInput, modifyText]
[UpdateTracker:9788087] Update Tracker - [Pathway:1566948] Elastic fibre formation - v44:[modifyText, updateContainedPathway, updateContainedRLE, updateIndirectRLE]
[UpdateTracker:9787912] Update Tracker - [BlackBoxEvent:187213] Synthesis of GAG polyprotein - v44:[add_removeOutput]
[UpdateTracker:9787732] Update Tracker - [Pathway:2500257] Resolution of Sister Chromatid Cohesion - v44:[updateContainedRLE]
[UpdateTracker:9787903] Update Tracker - [Reaction:173771] Formation of RTC (Reverse Transcription Complex) - v44:[add_removeOutput]
[UpdateTracker:9787718] Update Tracker - [Reaction:174374] MTR transfers CH3 from MeCbl to HCYS - v44:[add_removeInput, add_removeOutput, add_removeSummation]
[UpdateTracker:9787549] Update Tracker - [Reaction:164943] Nef mediated activation of the T-cell receptor - v44:[add_removeInput]
[UpdateTracker:9787867] Update Tracker - [Pathway:1989781] PPARA activates gene expression - v44:[updateContainedRLE]
[UpdateTracker:9788075] Update Tracker - [Pathway:449147] Signaling by Interleukins - v44:[updateIndirectRLE]
[UpdateTracker:9788112] Update Tracker - [Reaction:176494] SULTs transfer (SO4)2- group to 27HCHOL - v44:[modifyText]
[UpdateTracker:9787918] Update Tracker - [Reaction:114577] Binding of GPVI:Fc Epsilon R1 gamma receptor complex with collagen - v44:[add_removeInput]
[UpdateTracker:9787708] Update Tracker - [Pathway:2467813] Separation of Sister Chromatids - v44:[updateContainedRLE]
[UpdateTracker:9788070] Update Tracker - [Pathway:933541] TRAF6 mediated IRF7 activation - v44:[updateContainedRLE]
[UpdateTracker:9787689] Update Tracker - [Pathway:933542] TRAF6 mediated NF-kB activation - v44:[updateContainedRLE]
[UpdateTracker:9788061] Update Tracker - [Pathway:196819] Vitamin B1 (thiamin) metabolism - v44:[updateContainedRLE]
[UpdateTracker:9787852] Update Tracker - [Pathway:175474] Assembly Of The HIV Virion - v44:[removeHasEvent, updateIndirectRLE]
[UpdateTracker:9787801] Update Tracker - [Reaction:110353] Displacement of MBD4 glycosylase by APEX1 at the AP site - v44:[add_removeOutput]
[UpdateTracker:9788022] Update Tracker - [Pathway:163841] Gamma carboxylation, hypusine formation and arylsulfatase activation - v44:[updateIndirectRLE]
[UpdateTracker:9787996] Update Tracker - [Pathway:422356] Regulation of insulin secretion - v44:[removeHasEvent, updateContainedRLE, updateIndirectRLE]
[UpdateTracker:9788014] Update Tracker - [Reaction:373074] Receptor CCR9 binds CCL25 ligand - v44:[add_removeInput]
[UpdateTracker:9787742] Update Tracker - [Pathway:2129379] Molecules associated with elastic fibres - v44:[modifyText, updateContainedRLE]
[UpdateTracker:9787530] Update Tracker - [Pathway:110313] Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template - v44:[updateIndirectRLE]
[UpdateTracker:9788092] Update Tracker - [Pathway:189451] Heme biosynthesis - v44:[updateContainedRLE]
[UpdateTracker:9787640] Update Tracker - [Reaction:114263] Oligomerization of BAK at the mitochondrial membrane - v44:[modifyText]
[UpdateTracker:9787989] Update Tracker - [Pathway:201451] Signaling by BMP - v44:[updateContainedRLE]
[UpdateTracker:9787671] Update Tracker - [Reaction:212552] Caspase 3-mediated cleavage of PKC delta - v44:[add_removeInput]
[UpdateTracker:9787920] Update Tracker - [Pathway:210745] Regulation of gene expression in beta cells - v44:[updateContainedRLE]
[UpdateTracker:9788002] Update Tracker - [BlackBoxEvent:211461] HNF1A-dependent synthesis of the L isoform of PKLR protein - v44:[add_removeRegulator]
[UpdateTracker:9787725] Update Tracker - [Reaction:168848] tBID binds to inactive BAK protein - v44:[modifyText]
[UpdateTracker:9787632] Update Tracker - [Reaction:139909] Translocation of BMF to mitochondria - v44:[addLiteratureReference, add_removeInput, add_removeOutput, modifyText]
[UpdateTracker:9787902] Update Tracker - [Reaction:189425] UROD decarboxylates URO3 to COPRO3 - v44:[modifyText]
[UpdateTracker:9788006] Update Tracker - [Pathway:420597] Nectin/Necl trans heterodimerization - v44:[updateContainedRLE]
[UpdateTracker:9787951] Update Tracker - [Reaction:374922] Noradrenalin synaptic vesicle docking and priming - v44:[add_removeInput]
[UpdateTracker:9787667] Update Tracker - [Pathway:174154] APC/C:Cdc20 mediated degradation of Securin - v44:[updateContainedRLE]
[UpdateTracker:9787941] Update Tracker - [Pathway:111446] Activation of BIM and translocation to mitochondria - v44:[updateContainedRLE]
[UpdateTracker:9787938] Update Tracker - [Pathway:445717] Aquaporin-mediated transport - v44:[updateIndirectRLE]
[UpdateTracker:9787990] Update Tracker - [Reaction:939763] P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane - v44:[add_removeInput, add_removeOutput]
[UpdateTracker:9787779] Update Tracker - [Pathway:70370] Galactose catabolism - v44:[addHasEvent]
[UpdateTracker:9787845] Update Tracker - [Pathway:196025] Formation of annular gap junctions - v44:[updateContainedRLE]
[UpdateTracker:9787928] Update Tracker - [Reaction:169895] Crk's SH3 domain engages C3G - v44:[removeInput]
[UpdateTracker:9787712] Update Tracker - [Reaction:2424487] Phosphorylation of PLC-gamma by p-BTK/p-SYK - v44:[addLiteratureReference]
[UpdateTracker:9787556] Update Tracker - [Reaction:201640] Caspase-mediated cleavage of farnesyltransferase/geranyl- geranyltransferase subunit alpha - v44:[removeInput]
[UpdateTracker:9787911] Update Tracker - [Pathway:210744] Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells - v44:[updateContainedRLE]
[UpdateTracker:9787703] Update Tracker - [Reaction:73945] FAS-mediated dimerization of procaspase-8 - v44:[addInput, addLiteratureReference, add_removeOutput, modifyText]
[UpdateTracker:9788098] Update Tracker - [BlackBoxEvent:140214] TP53 stimulates PMAIP1 (NOXA) expression - v44:[modifyText]
[UpdateTracker:9787642] Update Tracker - [Reaction:209573] p75NTR:NgR complex interacts with the axonal inhibitor LINGO1 - v44:[add_removeInput]
[UpdateTracker:9787631] Update Tracker - [Pathway:1234174] Cellular response to hypoxia - v44:[updateIndirectRLE]
[UpdateTracker:9787531] Update Tracker - [Pathway:75892] Platelet Adhesion to exposed collagen - v44:[modifyText, updateContainedRLE]
[UpdateTracker:9787831] Update Tracker - [Pathway:162592] Integration of provirus - v44:[updateContainedRLE, updateIndirectRLE]
[UpdateTracker:9787660] Update Tracker - [Reaction:1067645] Jaks associate with IL6RB (gp130) - v44:[add_removeInput]
[UpdateTracker:9787605] Update Tracker - [Reaction:210426] Glutamate synaptic vesicle docking and priming - v44:[add_removeInput]
[UpdateTracker:9787614] Update Tracker - [Pathway:196854] Metabolism of vitamins and cofactors - v44:[updateContainedPathway]
[UpdateTracker:9787695] Update Tracker - [Pathway:2172127] DAP12 interactions - v44:[updateContainedRLE, updateIndirectRLE]
[UpdateTracker:9787548] Update Tracker - [Reaction:196753] 2xPPCS ligates PPanK with Cys - v44:[modifyText]
[UpdateTracker:9787891] Update Tracker - [Reaction:139918] Phosphorylation of BIM by JNK - v44:[add_removeOutput, modifyText]
[UpdateTracker:9787544] Update Tracker - [BlackBoxEvent:210788] HNF1B- and FGF10-dependent synthesis of PTF1A protein - v44:[add_removeRegulator]
[UpdateTracker:9787897] Update Tracker - [Reaction:936895] ATP7B transports cytosolic Cu2+ to Golgi lumen - v44:[modifyText]
[UpdateTracker:9788027] Update Tracker - [Reaction:964958] 2xPDXK:2xZn2+ phosphorylates PXA - v44:[modifyText]
[UpdateTracker:9787866] Update Tracker - [Pathway:111448] Activation of NOXA and translocation to mitochondria - v44:[updateContainedRLE]
[UpdateTracker:9787723] Update Tracker - [Pathway:168928] DDX58/IFIH1-mediated induction of interferon-alpha/beta - v44:[updateIndirectRLE]
[UpdateTracker:9787954] Update Tracker - [BlackBoxEvent:211272] FOXOA2-, MAFA-, and PAX6-dependent synthesis of PDX1 protein - v44:[add_removeRegulator]
[UpdateTracker:9787810] Update Tracker - [Reaction:195418] NRP-2 associates with VEGFR1 forming complexes on cell surface - v44:[add_removeInput]
[UpdateTracker:9788029] Update Tracker - [Pathway:2219528] PI3K/AKT Signaling in Cancer - v44:[updateIndirectRLE]
[UpdateTracker:9787908] Update Tracker - [Reaction:170846] TGFBR2 recruits TGFBR1 - v44:[addLiteratureReference, modifyText]
[UpdateTracker:9787939] Update Tracker - [Pathway:372708] p130Cas linkage to MAPK signaling for integrins - v44:[updateContainedRLE]
[UpdateTracker:9787594] Update Tracker - [Pathway:198745] Signalling to STAT3 - v44:[updateContainedRLE]
[UpdateTracker:9787634] Update Tracker - [Reaction:374214] Receptors CXCR4 and 7 bind CXCL12 ligand - v44:[add_removeInput]
[UpdateTracker:9787734] Update Tracker - [Pathway:190873] Gap junction degradation - v44:[updateContainedRLE, updateIndirectRLE]
[UpdateTracker:9787751] Update Tracker - [Pathway:202733] Cell surface interactions at the vascular wall - v44:[updateContainedRLE]
[UpdateTracker:9787767] Update Tracker - [Reaction:2167872] PP1CC dephosphorylates TGFBR1 - v44:[add_removeOutput]
[UpdateTracker:9787983] Update Tracker - [Reaction:418365] ATP2A1-3 transport cytosolic Ca2+ to dense tubular network lumen - v44:[modifyText]
[UpdateTracker:9787536] Update Tracker - [Pathway:169893] Prolonged ERK activation events - v44:[updateIndirectRLE]
[UpdateTracker:9787953] Update Tracker - [Pathway:1266738] Developmental Biology - v44:[updateIndirectRLE]
[UpdateTracker:9787597] Update Tracker - [Pathway:110312] Translesion synthesis by REV1 - v44:[updateContainedRLE]
[UpdateTracker:9787691] Update Tracker - [Pathway:382556] ABC-family proteins mediated transport - v44:[updateIndirectRLE]
[UpdateTracker:9787849] Update Tracker - [Pathway:176034] Interactions of Tat with host cellular proteins - v44:[updateContainedRLE]
[UpdateTracker:9787724] Update Tracker - [Pathway:1643685] Disease - v44:[add_removeHasEvent]
[UpdateTracker:9787904] Update Tracker - [Pathway:111457] Release of apoptotic factors from the mitochondria - v44:[updateContainedRLE]
[UpdateTracker:9788111] Update Tracker - [Pathway:165159] MTOR signalling - v44:[updateContainedRLE, updateIndirectRLE]
[UpdateTracker:9787621] Update Tracker - [BlackBoxEvent:383313] Glucagon-like Peptide 1 is secreted from intestinal L cells - v44:[add_removeOutput]
[UpdateTracker:9788045] Update Tracker - [Reaction:507870] Aquaporins passively transport water out of cells - v44:[addLiteratureReference, modifyText]
[UpdateTracker:9787857] Update Tracker - [Pathway:400206] Regulation of lipid metabolism by PPARalpha - v44:[updateIndirectRLE]
[UpdateTracker:9787824] Update Tracker - [Pathway:109582] Hemostasis - v44:[updateContainedPathway, updateIndirectRLE]
[UpdateTracker:9787946] Update Tracker - [Reaction:997381] TDPK phosphorylates ThDP to ThTP - v44:[modifyText]
[UpdateTracker:9787876] Update Tracker - [Reaction:77090] Methylation of GMP-cap by RNA Methyltransferase - v44:[add_removeOutput]
[UpdateTracker:9787987] Update Tracker - [Reaction:77073] SPT5 subunit of Pol II binds the RNA triphosphatase (RTP) - v44:[add_removeInput]
[UpdateTracker:9787739] Update Tracker - [Pathway:74160] Gene expression (Transcription) - v44:[addHasEvent, updateContainedPathway, updateIndirectRLE]
[UpdateTracker:9787832] Update Tracker - [Reaction:162914] Myristoylation of Nef - v44:[add_removeInput, add_removeOutput]
[UpdateTracker:9787901] Update Tracker - [Pathway:112040] G-protein mediated events - v44:[updateIndirectRLE]
[UpdateTracker:9787761] Update Tracker - [Pathway:416482] G alpha (12/13) signalling events - v44:[updateContainedRLE]
[UpdateTracker:9787564] Update Tracker - [Reaction:200954] Nef Binds and activates the Src-family tyrosine kinase Lck - v44:[add_removeInput]
[UpdateTracker:9788010] Update Tracker - [Reaction:140216] Translocation of PMAIP1 (NOXA) to mitochondria - v44:[addLiteratureReference]
[UpdateTracker:9787608] Update Tracker - [Pathway:196071] Metabolism of steroid hormones - v44:[modifyText, removeHasEvent]
[UpdateTracker:9787782] Update Tracker - [Reaction:420593] PVR:PVRL3 trans heterodimer interaction - v44:[add_removeInput, modifyText]
[UpdateTracker:9787529] Update Tracker - [Reaction:190168] HMBL spontaneously transforms to URO1 - v44:[modifyText]
[UpdateTracker:9787672] Update Tracker - [Pathway:1257604] PIP3 activates AKT signaling - v44:[updateIndirectRLE]
[UpdateTracker:9787914] Update Tracker - [Reaction:400492] PCSK1 hydrolyzes proGIP to GIP - v44:[add_removeCatalystActivity]
[UpdateTracker:9788090] Update Tracker - [Reaction:381608] cAMP activates EPAC2 - v44:[add_removeInput]
[UpdateTracker:9787895] Update Tracker - [Reaction:421831] trans-Golgi Network Coat Assembly - v44:[add_removeInput]
[UpdateTracker:9787669] Update Tracker - [Reaction:198347] AKT phosphorylates BAD - v44:[addLiteratureReference, modifyText]
[UpdateTracker:9787736] Update Tracker - [Pathway:434316] Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion - v44:[updateContainedRLE]
[UpdateTracker:9787927] Update Tracker - [Reaction:421835] trans-Golgi Network Vesicle Scission - v44:[add_removeOutput]
[UpdateTracker:9787967] Update Tracker - [Reaction:110307] REV1 binds AP-dsDNA - v44:[add_removeInput]
[UpdateTracker:9787612] Update Tracker - [Pathway:399719] Trafficking of AMPA receptors - v44:[updateContainedRLE]
[UpdateTracker:9787628] Update Tracker - [BlackBoxEvent:381799] Synthesis of Preproglucagon in intestinal L cells - v44:[add_removeRegulator]
[UpdateTracker:9787864] Update Tracker - [Reaction:170978] p-FRS2:CRKL binds C3G - v44:[add_removeInput]
[UpdateTracker:9787627] Update Tracker - [Pathway:1059683] Interleukin-6 signaling - v44:[updateContainedRLE]
[UpdateTracker:9787905] Update Tracker - [Reaction:432707] trans-Golgi Network Lysosomal Vesicle Scission - v44:[add_removeOutput]
[UpdateTracker:9788046] Update Tracker - [Reaction:189439] ALAD condenses 2 dALAs to form PBG - v44:[modifyText]
[UpdateTracker:9787554] Update Tracker - [Pathway:110328] Recognition and association of DNA glycosylase with site containing an affected pyrimidine - v44:[updateContainedRLE]
[UpdateTracker:9787570] Update Tracker - [BlackBoxEvent:1368140] Expression of PPARGC1A (PGC-1alpha) - v44:[modifyText]
[UpdateTracker:9787863] Update Tracker - [BlackBoxEvent:210886] NEUROG3-dependent synthesis of PAX4 protein - v44:[add_removeOutput]
[UpdateTracker:9787706] Update Tracker - [Pathway:68877] Mitotic Prometaphase - v44:[updateIndirectRLE]
[UpdateTracker:9787962] Update Tracker - [Pathway:2173788] Downregulation of TGF-beta receptor signaling - v44:[addHasEvent, addLiteratureReference, modifyText, updateContainedRLE]
[UpdateTracker:9787527] Update Tracker - [Pathway:73930] Abasic sugar-phosphate removal via the single-nucleotide replacement pathway - v44:[updateIndirectRLE]
[UpdateTracker:9787960] Update Tracker - [Pathway:69242] S Phase - v44:[updateContainedPathway, updateIndirectRLE]
[UpdateTracker:9787818] Update Tracker - [Pathway:373076] Class A/1 (Rhodopsin-like receptors) - v44:[updateIndirectRLE]
[UpdateTracker:9788054] Update Tracker - [Reaction:168849] tBID binds to inactive BAX protein - v44:[addLiteratureReference, modifyText]
[UpdateTracker:9787833] Update Tracker - [Reaction:199144] Nectin 2 binds CD226 - v44:[add_removeInput]
[UpdateTracker:9788071] Update Tracker - [Reaction:975340] GABR heteropentamers:GABA transport Cl- from extracellular region to cytosol - v44:[modifyText]
[UpdateTracker:9787535] Update Tracker - [Pathway:373760] L1CAM interactions - v44:[updateIndirectRLE]
[UpdateTracker:9787599] Update Tracker - [Reaction:199112] CRTAM binds to NECL2 - v44:[add_removeInput]
[UpdateTracker:9787934] Update Tracker - [Pathway:2173796] SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription - v44:[updateContainedRLE]
[UpdateTracker:9787666] Update Tracker - [Pathway:888590] GABA synthesis, release, reuptake and degradation - v44:[updateContainedRLE]
[UpdateTracker:9788033] Update Tracker - [BlackBoxEvent:174202] Degradation of multiubiquitinated Securin - v44:[add_removeInput]
[UpdateTracker:9787893] Update Tracker - [Reaction:204662] DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A - v44:[add_removeInput]
[UpdateTracker:9787868] Update Tracker - [Pathway:975871] MyD88 cascade initiated on plasma membrane - v44:[updateIndirectRLE]
[UpdateTracker:9788008] Update Tracker - [Pathway:187037] Signaling by NTRK1 (TRKA) - v44:[updateIndirectRLE]
[UpdateTracker:9787788] Update Tracker - [Pathway:2122947] NOTCH1 Intracellular Domain Regulates Transcription - v44:[updateContainedRLE]
[UpdateTracker:9787585] Update Tracker - [Pathway:1462054] Alpha-defensins - v44:[updateContainedRLE]
[UpdateTracker:9787840] Update Tracker - [Reaction:175250] Suicidal integration leading to smaller circles of viral DNA - v44:[add_removeOutput]
[UpdateTracker:9787925] Update Tracker - [Pathway:167590] Nef Mediated CD4 Down-regulation - v44:[updateContainedRLE]
[UpdateTracker:9787870] Update Tracker - [Reaction:166538] The bound receptor dimerizes - v44:[add_removeInput]
[UpdateTracker:9788100] Update Tracker - [Pathway:450282] MAPK targets/ Nuclear events mediated by MAP kinases - v44:[updateIndirectRLE]
[UpdateTracker:9787982] Update Tracker - [Reaction:2160932] SMURF1 binds phosphorylated PARD6A - v44:[add_removeInput]
[UpdateTracker:9787591] Update Tracker - [Reaction:167566] Nef mediated disruption of CD4:Lck Complex - v44:[add_removeInput]
[UpdateTracker:9787521] Update Tracker - [Pathway:109703] PKB-mediated events - v44:[updateIndirectRLE]
[UpdateTracker:9787808] Update Tracker - [Reaction:1980039] NOTCH1 binds DLL1 - v44:[modifyText]
[UpdateTracker:9787678] Update Tracker - [Reaction:1591234] ZBP1 binds cytosolic DNA - v44:[add_removeInput]
[UpdateTracker:9787694] Update Tracker - [Pathway:73887] Death Receptor Signalling - v44:[updateIndirectRLE]
[UpdateTracker:9787926] Update Tracker - [Reaction:201422] Phospho-R-Smad1/5/8 forms a complex with Co-Smad - v44:[modifyText]
[UpdateTracker:9787560] Update Tracker - [Reaction:110171] MBD4 glycosylase mediated recognition and binding of an uracil opposite to a guanine at CpG sequences - v44:[add_removeInput]
[UpdateTracker:9787651] Update Tracker - [Reaction:174144] Ubiquitination of Securin by phospho-APC/C:Cdc20 complex - v44:[addLiteratureReference, add_removeOutput, modifyText]
[UpdateTracker:9787626] Update Tracker - [BlackBoxEvent:210773] PDX1-dependent synthesis of NR5A2 protein - v44:[add_removeOutput]
[UpdateTracker:9787826] Update Tracker - [Reaction:189457] Mitochondrial intermembrane PRIN9 translocates to mitochondrial matrix - v44:[modifyText]
[UpdateTracker:9788060] Update Tracker - [Pathway:162599] Late Phase of HIV Life Cycle - v44:[addHasEvent, updateContainedPathway, updateContainedRLE, updateIndirectRLE]
[UpdateTracker:9787935] Update Tracker - [Pathway:175567] Integration of viral DNA into host genomic DNA - v44:[updateContainedRLE]
[UpdateTracker:9787858] Update Tracker - [Pathway:1606322] ZBP1(DAI) mediated induction of type I IFNs - v44:[updateContainedRLE, updateIndirectRLE]
[UpdateTracker:9787625] Update Tracker - [Pathway:422085] Synthesis, secretion, and deacylation of Ghrelin - v44:[updateContainedRLE]
[UpdateTracker:9787992] Update Tracker - [Pathway:373755] Semaphorin interactions - v44:[updateIndirectRLE]
[UpdateTracker:9787875] Update Tracker - [Reaction:184392] N-myristoylation of GAG polyprotein by NMT2 - v44:[add_removeInput, add_removeOutput]
[UpdateTracker:9788035] Update Tracker - [Reaction:1067646] JAK1,JAK2,(TYK2) bind IL6ST - v44:[add_removeInput]
[UpdateTracker:9787679] Update Tracker - [Reaction:2169004] Smad7 binds SMURF1 - v44:[add_removeInput]
[UpdateTracker:9787899] Update Tracker - [Pathway:114294] Activation, translocation and oligomerization of BAX - v44:[modifyText, updateContainedRLE]
[UpdateTracker:9787541] Update Tracker - [Reaction:936802] ATP7A transports cytosolic Cu2+ to extracellular region - v44:[modifyText]
[UpdateTracker:9787557] Update Tracker - [Pathway:674695] RNA Polymerase II Pre-transcription Events - v44:[updateContainedRLE]
[UpdateTracker:9787778] Update Tracker - [BlackBoxEvent:211734] Ubiquitination of PAK-2p34 - v44:[add_removeOutput, modifyText]
[UpdateTracker:9788076] Update Tracker - [BlackBoxEvent:211476] HNF1A-dependent synthesis of GLUT2 protein - v44:[add_removeRegulator]
[UpdateTracker:9788021] Update Tracker - [Reaction:110311] POLZ extends translesion synthesis - v44:[add_removeOutput]
[UpdateTracker:9788017] Update Tracker - [Pathway:190828] Gap junction trafficking - v44:[updateIndirectRLE]
[UpdateTracker:9787622] Update Tracker - [Pathway:71291] Metabolism of amino acids and derivatives - v44:[removeHasEvent, updateIndirectRLE]
[UpdateTracker:9787838] Update Tracker - [Reaction:114352] Sequestration of tBID by BCL-2 - v44:[modifyText]
[UpdateTracker:9788091] Update Tracker - [Pathway:418890] Role of second messengers in netrin-1 signaling - v44:[updateContainedRLE]
[UpdateTracker:9787645] Update Tracker - [Reaction:198870] SLC23A1,2 cotransports AscH-, 2Na+ from extracellular region to cytosol - v44:[modifyText]
[UpdateTracker:9787812] Update Tracker - [Pathway:205043] NRIF signals cell death from the nucleus - v44:[updateContainedRLE]
[UpdateTracker:9787770] Update Tracker - [Reaction:112434] Formation of DSIF complex - v44:[add_removeInput]
[UpdateTracker:9787780] Update Tracker - [Pathway:165181] Inhibition of TSC complex formation by PKB - v44:[updateContainedRLE]
[UpdateTracker:9788016] Update Tracker - [Reaction:109699] PI3K-containing complexes phosphorylate PIP2 to PIP3 - v44:[add_removeInput]
[UpdateTracker:9787610] Update Tracker - [Reaction:196950] 2xTRAP hydrolyzes FMN to RIB - v44:[modifyText]
[UpdateTracker:9787997] Update Tracker - [Reaction:1973968] Beta-defensins 4A and 103 bind CCR2 - v44:[add_removeInput]
[UpdateTracker:9787828] Update Tracker - [Reaction:432706] trans-Golgi Network Lysosome Vesicle Destined Membrane Coat Assembly - v44:[add_removeInput]
[UpdateTracker:9787711] Update Tracker - [Pathway:163685] Integration of energy metabolism - v44:[updateContainedPathway, updateIndirectRLE]
[UpdateTracker:9788067] Update Tracker - [BlackBoxEvent:182171] Degradation of CD8 - v44:[add_removeOutput]
[UpdateTracker:9787965] Update Tracker - [Pathway:112043] PLC beta mediated events - v44:[updateContainedRLE]
[UpdateTracker:9787837] Update Tracker - [Pathway:432047] Passive transport by Aquaporins - v44:[updateContainedRLE]
[UpdateTracker:9787714] Update Tracker - [Pathway:180534] Vpu mediated degradation of CD4 - v44:[updateContainedRLE]
[UpdateTracker:9787894] Update Tracker - [Pathway:1181150] Signaling by NODAL - v44:[updateContainedRLE]
[UpdateTracker:9787887] Update Tracker - [Reaction:200879] Formation of a Nef:ARF1:CD4 complex - v44:[add_removeInput]
[UpdateTracker:9787601] Update Tracker - [Reaction:114275] Oligomerization of BAX at the mitochondrial membrane - v44:[modifyText]
[UpdateTracker:9787603] Update Tracker - [Reaction:508163] BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 - v44:[addLiteratureReference, modifyText]
[UpdateTracker:9787813] Update Tracker - [Pathway:1236394] Signaling by ERBB4 - v44:[updateIndirectRLE]
[UpdateTracker:9787735] Update Tracker - [Pathway:2173791] TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) - v44:[updateContainedRLE]
[UpdateTracker:9788073] Update Tracker - [Pathway:210500] Glutamate Neurotransmitter Release Cycle - v44:[updateContainedRLE]
[UpdateTracker:9787593] Update Tracker - [Reaction:110172] MBD4 glycosylase mediated recognition and binding of a thymine opposite to a guanine at CpG sequences - v44:[add_removeInput]
[UpdateTracker:9787697] Update Tracker - [Pathway:400511] Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP) - v44:[updateContainedRLE]
[UpdateTracker:9788103] Update Tracker - [BlackBoxEvent:2106586] WWTR1:SMAD stimulates transcription of SERPINE1 while TGIF:SMAD and SMAD7 inhibit it - v44:[addLiteratureReference, addRegulator, modifyText]
[UpdateTracker:9788059] Update Tracker - [Reaction:200858] Nef Binds and activates the Src-family tyrosine kinase Hck - v44:[add_removeInput]
[UpdateTracker:9787569] Update Tracker - [Pathway:180897] Vpr-mediated induction of apoptosis by mitochondrial outer membrane permeabilization - v44:[updateContainedRLE]
[UpdateTracker:9787769] Update Tracker - [Reaction:139895] tBID activates BAK protein - v44:[modifyText]
[UpdateTracker:9787713] Update Tracker - [Reaction:212380] Formation of TRAP coactivator complex - v44:[add_removeInput]
[UpdateTracker:9787575] Update Tracker - [BlackBoxEvent:211289] MAFA-, NKX2-2-, PAX6-, and PDX1-dependent synthesis of insulin precursor protein - v44:[add_removeRegulator]
[UpdateTracker:9787572] Update Tracker - [Pathway:177539] Autointegration results in viral DNA circles - v44:[updateContainedRLE]
[UpdateTracker:9787589] Update Tracker - [Pathway:418889] Caspase activation via Dependence Receptors in the absence of ligand - v44:[updateContainedRLE]
[UpdateTracker:9787558] Update Tracker - [Reaction:199131] PVR binds CD226 - v44:[add_removeInput]
[UpdateTracker:9787709] Update Tracker - [Reaction:1638821] PP2A-B56 dephosphorylates centromeric cohesin - v44:[addLiteratureReference, modifyText]
[UpdateTracker:9788086] Update Tracker - [Pathway:77075] RNA Pol II CTD phosphorylation and interaction with CE - v44:[updateContainedRLE]
[UpdateTracker:9787522] Update Tracker - [Reaction:164845] Suicidal integration leading to inverted circle formation - v44:[add_removeOutput]
[UpdateTracker:9787588] Update Tracker - [Pathway:71032] Propionyl-CoA catabolism - v44:[updateContainedRLE]
[UpdateTracker:9787752] Update Tracker - [Pathway:975634] Retinoid metabolism and transport - v44:[addHasEvent, updateContainedRLE]
[UpdateTracker:9787600] Update Tracker - [Reaction:114284] Release of Cytochrome c from mitochondria - v44:[modifyText]
[UpdateTracker:9787877] Update Tracker - [Pathway:1251985] Nuclear signaling by ERBB4 - v44:[updateContainedRLE]
[UpdateTracker:9787654] Update Tracker - [Pathway:164940] Nef mediated downregulation of MHC class I complex cell surface expression - v44:[updateContainedRLE]
[UpdateTracker:9787907] Update Tracker - [Pathway:216083] Integrin cell surface interactions - v44:[updateContainedRLE]
[UpdateTracker:9787661] Update Tracker - [Reaction:2167890] Smad7 recruits GADD34:PP1CC to phosphorylated TGF-beta receptor complex - v44:[add_removeInput]
[UpdateTracker:9787940] Update Tracker - [Reaction:193677] NRIF binds to p75NTR - v44:[add_removeInput]
[UpdateTracker:9787716] Update Tracker - [Pathway:77289] Mitochondrial Fatty Acid Beta-Oxidation - v44:[updateIndirectRLE]
[UpdateTracker:9787571] Update Tracker - [Reaction:141156] TRAIL-mediated dimerization of procaspase-8 - v44:[addInput, addLiteratureReference, add_removeOutput, modifyText]
[UpdateTracker:9787615] Update Tracker - [Reaction:965019] 2xPNPO:2xFMN oxidizes PDXP to PXLP - v44:[modifyText]
[UpdateTracker:9787740] Update Tracker - [Pathway:164939] Nef mediated downregulation of CD28 cell surface expression - v44:[updateContainedRLE]
[UpdateTracker:9787929] Update Tracker - [BlackBoxEvent:167601] Degradation of CD4 - v44:[add_removeOutput]
[UpdateTracker:9788004] Update Tracker - [Reaction:212432] Formation of DRIP coactivator complex - v44:[add_removeInput]
[UpdateTracker:9787874] Update Tracker - [Reaction:210300] Interaction of DAP12 and TREM2 - v44:[modifyText]
[UpdateTracker:9787835] Update Tracker - [Pathway:181430] Norepinephrine Neurotransmitter Release Cycle - v44:[updateContainedRLE]
[UpdateTracker:9787884] Update Tracker - [Reaction:212352] Formation of ARC coactivator complex - v44:[add_removeInput]
[UpdateTracker:9787539] Update Tracker - [Pathway:418217] G beta:gamma signalling through PLC beta - v44:[updateContainedRLE]
[UpdateTracker:9787595] Update Tracker - [Reaction:204617] DHPS tetramer synthesizes EIF5A and spermidine from Dhp-K50-EIF5A - v44:[add_removeInput, add_removeOutput]
[UpdateTracker:9787759] Update Tracker - [Reaction:139906] Activation of BAD by calcineurin - v44:[addInput, add_removeOutput, modifyText]
[UpdateTracker:9787829] Update Tracker - [Reaction:157640] NEXT2 is cleaved to produce NICD2 - v44:[modifyText]
[UpdateTracker:9787781] Update Tracker - [Pathway:109581] Apoptosis - v44:[updateContainedPathway, updateIndirectRLE]
[UpdateTracker:9788064] Update Tracker - [Reaction:549322] OCT1 transports organic cations out of hepatic cells - v44:[add_removeLiteratureReference]
[UpdateTracker:9787760] Update Tracker - [Pathway:157118] Signaling by NOTCH - v44:[updateContainedPathway]
[UpdateTracker:9787561] Update Tracker - [Reaction:204647] DHPS tetramer synthesizes Dhp-K50-EIF5A from EIF5A and spermidine - v44:[add_removeInput, add_removeOutput]
[UpdateTracker:9787553] Update Tracker - [Reaction:2399982] AKT1 E17K mutant phosphorylates TSC2, inhibiting it - v44:[add_removeInput]
[UpdateTracker:9787975] Update Tracker - [BlackBoxEvent:210824] HNF6-dependent synthesis of HNF1B protein - v44:[add_removeOutput]
[UpdateTracker:9787688] Update Tracker - [Pathway:381771] Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) - v44:[updateContainedRLE]
[UpdateTracker:9787583] Update Tracker - [BlackBoxEvent:2161293] Tropoelastin forms aggregate globules - v44:[modifyText]
[UpdateTracker:9787611] Update Tracker - [Reaction:139919] Translocation of BIM to mitochondria - v44:[addLiteratureReference, add_removeInput, add_removeOutput, modifyText]
[UpdateTracker:9787805] Update Tracker - [Reaction:622382] PIP2 hydrolysis - v44:[add_removeInput]
[UpdateTracker:9788097] Update Tracker - [Reaction:212356] Formation of CSL-NICD coactivator complex - v44:[add_removeInput]
[UpdateTracker:9787674] Update Tracker - [Reaction:202947] Caspase mediated cleavage of APC - v44:[add_removeInput, add_removeOutput]
[UpdateTracker:9788043] Update Tracker - [Reaction:114392] Dissociation of Caspase-7 from DIABLO:XIAP:Caspase-7 - v44:[modifyText]
[UpdateTracker:9787665] Update Tracker - [Pathway:189445] Metabolism of porphyrins - v44:[updateIndirectRLE]
[UpdateTracker:9788105] Update Tracker - [Reaction:114688] PLC-beta hydrolyses PIP2 to DAG and IP3 - v44:[add_removeInput]
[UpdateTracker:9787988] Update Tracker - [Pathway:202403] TCR signaling - v44:[updateIndirectRLE]
[UpdateTracker:9787881] Update Tracker - [Pathway:375276] Peptide ligand-binding receptors - v44:[updateContainedRLE, updateIndirectRLE]
[UpdateTracker:9787620] Update Tracker - [Pathway:169131] Inhibition of PKR - v44:[updateContainedRLE]
[UpdateTracker:9787545] Update Tracker - [Pathway:1461973] Defensins - v44:[updateIndirectRLE]
[UpdateTracker:9787641] Update Tracker - [Reaction:2396599] Recruitment of GRB2:SOS to p-5Y-LAT - v44:[addLiteratureReference, add_removeInput]
[UpdateTracker:9788026] Update Tracker - [Reaction:114440] Dissociation of DIABLO:XIAP from the apoptosome complex - v44:[addLiteratureReference, modifyText]
[UpdateTracker:9787756] Update Tracker - [Reaction:190182] UROD decarboxylates URO1 to COPRO1 - v44:[modifyText]
[UpdateTracker:9787964] Update Tracker - [Reaction:83586] FASL:FAS Receptor Trimer:FADD complex binds pro-Caspase-8 - v44:[addRegulator]
[UpdateTracker:9787948] Update Tracker - [Reaction:202164] Translocation of PDK1 to Plasma membrane - v44:[modifyText]
[UpdateTracker:9788032] Update Tracker - [Pathway:2219530] Constitutive Signaling by Aberrant PI3K in Cancer - v44:[updateContainedRLE]
[UpdateTracker:9787794] Update Tracker - [Pathway:111464] SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes - v44:[updateContainedRLE]
[UpdateTracker:9788001] Update Tracker - [Reaction:196929] FLAD1 phosphorylates FMN - v44:[modifyText]
[UpdateTracker:9788107] Update Tracker - [Reaction:75146] TRAIL:TRAIL Receptor Trimer:FADD complex binds procaspase-8 - v44:[addRegulator]
[UpdateTracker:9787860] Update Tracker - [BlackBoxEvent:212917] Proteasome mediated degradation of PAK-2p34 - v44:[add_removeInput]
[UpdateTracker:9787943] Update Tracker - [Pathway:196783] Coenzyme A biosynthesis - v44:[updateContainedRLE]
[UpdateTracker:9788037] Update Tracker - [Reaction:2395328] LTBP1, LTBP3 bind TGF-Beta - v44:[modifyText]
[UpdateTracker:9787936] Update Tracker - [Reaction:507868] Aquaporins passively transport water into cells - v44:[addLiteratureReference, modifyText]
[UpdateTracker:9787730] Update Tracker - [Pathway:69275] G2/M Transition - v44:[addHasEvent]
[UpdateTracker:9788051] Update Tracker - [Reaction:189467] Cytosolic COPRO3 translocates to mitochondrial intermembrane space - v44:[modifyText]
[UpdateTracker:9787692] Update Tracker - [Reaction:2176445] SMURF2 binds SMAD2 - v44:[add_removeInput]
[UpdateTracker:9787738] Update Tracker - [Reaction:381262] Formation of PPARG:RXRA heterodimer (ARF6 complex) - v44:[add_removeInput]
[UpdateTracker:9788019] Update Tracker - [Reaction:180602] Association of Vif with APOBEC3G - v44:[add_removeInput]
[UpdateTracker:9788063] Update Tracker - [Reaction:447074] AMPK phosphorylates Raptor in the mTORC1 complex - v44:[add_removeInput, add_removeOutput]
[UpdateTracker:9787873] Update Tracker - [Reaction:975311] HTR3 pentamers:5HT transport Na+,K+,Ca2+ - v44:[modifyText]
[UpdateTracker:9787793] Update Tracker - [Pathway:397014] Muscle contraction - v44:[updateIndirectRLE]
[UpdateTracker:9787815] Update Tracker - [Pathway:69278] Cell Cycle, Mitotic - v44:[updateContainedPathway]
[UpdateTracker:9788020] Update Tracker - [Reaction:194818] botA LC cleaves target cell SNAP25 - v44:[add_removeInput, add_removeOutput]
[UpdateTracker:9787624] Update Tracker - [Reaction:166542] beta-NGF dimer binds to TrkA receptor - v44:[add_removeInput]
[UpdateTracker:9787790] Update Tracker - [Pathway:75108] Activation, myristolyation of BID and translocation to mitochondria - v44:[updateContainedRLE]
[UpdateTracker:9787854] Update Tracker - [BlackBoxEvent:140217] Transactivation of PMAIP1 (NOXA) by E2F1 - v44:[modifyText]
[UpdateTracker:9787955] Update Tracker - [Pathway:198753] ERK/MAPK targets - v44:[updateContainedRLE]
[UpdateTracker:9787984] Update Tracker - [Pathway:162594] Early Phase of HIV Life Cycle - v44:[updateContainedRLE, updateIndirectRLE]
[UpdateTracker:9787707] Update Tracker - [Reaction:202541] p-S177,S181-IKKB:IKKA:pUb-NEMO phosphorylates IkB-alpha:NF-kB - v44:[addLiteratureReference, modifyText]
[UpdateTracker:9787923] Update Tracker - [Reaction:167630] Formation of Nef CD28 cytoplasmic tail complex - v44:[add_removeInput]
[UpdateTracker:9787930] Update Tracker - [Pathway:400508] Incretin synthesis, secretion, and inactivation - v44:[updateIndirectRLE]
[UpdateTracker:9787963] Update Tracker - [Reaction:420582] Necl-1:Nectin-1 trans heterodimer interaction - v44:[add_removeInput]
[UpdateTracker:9787842] Update Tracker - [Reaction:427910] ATP2A1-3 transport Ca2+ from cytosol to ER lumen - v44:[modifyText]
[UpdateTracker:9787682] Update Tracker - [Pathway:170834] Signaling by TGF-beta Receptor Complex - v44:[modifyText, updateContainedPathway, updateIndirectRLE]
[UpdateTracker:9787722] Update Tracker - [Pathway:111997] CaM pathway - v44:[updateContainedRLE]
[UpdateTracker:9788044] Update Tracker - [Pathway:164938] Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters - v44:[updateIndirectRLE]
[UpdateTracker:9787994] Update Tracker - [Pathway:177243] Interactions of Rev with host cellular proteins - v44:[updateIndirectRLE]
[UpdateTracker:9787720] Update Tracker - [Reaction:351863] Translocation of active caspase-8 to the mitochondrial membrane - v44:[add_removeInput, add_removeOutput]
[UpdateTracker:9787562] Update Tracker - [Pathway:68886] M Phase - v44:[updateContainedPathway]
[UpdateTracker:9787766] Update Tracker - [Pathway:180585] Vif-mediated degradation of APOBEC3G - v44:[updateContainedRLE]
[UpdateTracker:9787698] Update Tracker - [Pathway:373752] Netrin-1 signaling - v44:[updateIndirectRLE]
[UpdateTracker:9788047] Update Tracker - [Reaction:114671] vWF binds to collagen - v44:[add_removeInput]
[UpdateTracker:9787896] Update Tracker - [BlackBoxEvent:1235037] Expression of VEGFA - v44:[add_removeOutput]
[UpdateTracker:9787715] Update Tracker - [Reaction:381668] cAMP activates EPAC1 - v44:[add_removeInput]
[UpdateTracker:9788039] Update Tracker - [Pathway:71387] Metabolism of carbohydrates - v44:[updateContainedPathway]
[UpdateTracker:9787792] Update Tracker - [Pathway:549127] Organic cation transport - v44:[updateContainedRLE]
[UpdateTracker:9787576] Update Tracker - [Pathway:68875] Mitotic Prophase - v44:[addHasEvent]
[UpdateTracker:9787755] Update Tracker - [Reaction:170835] An anchoring protein, ZFYVE9 (SARA), recruits SMAD2/3 - v44:[add_removeInput]
[UpdateTracker:9787728] Update Tracker - [Pathway:937061] TRIF(TICAM1)-mediated TLR4 signaling - v44:[updateIndirectRLE]
[UpdateTracker:9788085] Update Tracker - [Pathway:194313] VEGF ligand-receptor interactions - v44:[updateIndirectRLE]
[UpdateTracker:9787719] Update Tracker - [Reaction:1834939] STING recruits TBK1 and IRF3 - v44:[addRegulator]
[UpdateTracker:9788013] Update Tracker - [Pathway:196843] Vitamin B2 (riboflavin) metabolism - v44:[updateContainedRLE]
[UpdateTracker:9787644] Update Tracker - [Pathway:2173793] Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer - v44:[modifyText, updateIndirectRLE]
[UpdateTracker:9787932] Update Tracker - [BlackBoxEvent:381798] PCSK1 hydrolyzes Proglucagon to Glucagon-like Peptide-1 - v44:[add_removeCatalystActivity]
[UpdateTracker:9787871] Update Tracker - [Pathway:195253] Degradation of beta-catenin by the destruction complex - v44:[updateContainedRLE]
[UpdateTracker:9787976] Update Tracker - [Pathway:418359] Reduction of cytosolic Ca++ levels - v44:[updateContainedRLE]
[UpdateTracker:9788099] Update Tracker - [Reaction:373705] Caspase cleavage of DCC - v44:[add_removeCatalystActivity]
[UpdateTracker:9788034] Update Tracker - [Reaction:373714] Cis-Heterodimerization of nephrin and KIRREL - v44:[add_removeInput]
[UpdateTracker:9787717] Update Tracker - [Reaction:917744] GABA loaded synaptic vesicle Docking and Priming - v44:[add_removeInput]
[UpdateTracker:9787607] Update Tracker - [Reaction:1912391] NICD1 is phosphorylated by CDK8 - v44:[modifyText]
[UpdateTracker:9788106] Update Tracker - [Reaction:114307] Release of SMAC (DIABLO) from mitochondria - v44:[add_removeSummation]
[UpdateTracker:9787696] Update Tracker - [Pathway:198323] AKT phosphorylates targets in the cytosol - v44:[updateContainedRLE]
[UpdateTracker:9787647] Update Tracker - [Pathway:112310] Neurotransmitter release cycle - v44:[updateIndirectRLE]
[UpdateTracker:9787807] Update Tracker - [Reaction:198731] ERK1/2 activates ELK1 - v44:[add_removeInput, add_removeOutput]
[UpdateTracker:9787977] Update Tracker - [Pathway:186763] Downstream signal transduction - v44:[updateContainedRLE]
[UpdateTracker:9787563] Update Tracker - [Pathway:195721] Signaling by WNT - v44:[updateIndirectRLE]
[UpdateTracker:9787980] Update Tracker - [Pathway:170968] Frs2-mediated activation - v44:[updateContainedRLE]
[UpdateTracker:9788078] Update Tracker - [Reaction:175117] 1-LTR circle formation - v44:[add_removeOutput]
[UpdateTracker:9787748] Update Tracker - [Pathway:880009] Interconversion of 2-oxoglutarate and 2-hydroxyglutarate - v44:[modifyText, removeHasEvent]
[UpdateTracker:9787879] Update Tracker - [Pathway:162906] HIV Infection - v44:[updateContainedPathway]
[UpdateTracker:9787856] Update Tracker - [Pathway:983705] Signaling by the B Cell Receptor (BCR) - v44:[updateIndirectRLE]
[UpdateTracker:9788068] Update Tracker - [Pathway:112399] IRS-mediated signalling - v44:[updateIndirectRLE]
[UpdateTracker:9787851] Update Tracker - [BlackBoxEvent:182263] Degradation of MHC I Complex - v44:[add_removeOutput]
[UpdateTracker:9787848] Update Tracker - [Pathway:75153] Apoptotic execution phase - v44:[updateContainedRLE, updateIndirectRLE]
[UpdateTracker:9787584] Update Tracker - [Pathway:264642] Acetylcholine Neurotransmitter Release Cycle - v44:[updateContainedRLE]
[UpdateTracker:9787524] Update Tracker - [Reaction:205118] TRAF6 polyubiquitinates NRIF - v44:[add_removeInput]
[UpdateTracker:9787974] Update Tracker - [Pathway:73857] RNA Polymerase II Transcription - v44:[updateIndirectRLE]
[UpdateTracker:9787958] Update Tracker - [Reaction:199216] SLC25A16 transports cytosolic CoA-SH to mitichondrial matrix - v44:[modifyText]
[UpdateTracker:9788088] Update Tracker - [Pathway:73928] Depyrimidination - v44:[updateIndirectRLE]
[UpdateTracker:9787978] Update Tracker - [Pathway:75157] FasL/ CD95L signaling - v44:[updateContainedRLE]
[UpdateTracker:9788055] Update Tracker - [Pathway:983712] Ion channel transport - v44:[addHasEvent, updateIndirectRLE]
[UpdateTracker:9787892] Update Tracker - [Reaction:178189] SMAD7 recruits GADD34:PP1 to phosphorylated TGFBR - v44:[add_removeInput]
[UpdateTracker:9787655] Update Tracker - [Reaction:139920] Translocation of tBID to mitochondria - v44:[addLiteratureReference, modifyText]
[UpdateTracker:9787968] Update Tracker - [Pathway:432720] Lysosome Vesicle Biogenesis - v44:[updateContainedRLE]
[UpdateTracker:9787658] Update Tracker - [Reaction:110453] Phosphorylation of PIP2 to PIP3 by Dp110 - v44:[add_removeInput]
[UpdateTracker:9787700] Update Tracker - [Reaction:398185] LARG binds plexin B1 - v44:[add_removeInput]
[UpdateTracker:9787517] Update Tracker - [Pathway:445355] Smooth Muscle Contraction - v44:[updateContainedRLE]
[UpdateTracker:9788041] Update Tracker - [Pathway:156581] Methylation - v44:[updateContainedRLE]
[UpdateTracker:9787909] Update Tracker - [Reaction:139899] Sequestration of BAD protein by 14-3-3 - v44:[addLiteratureReference, add_removeInput, modifyText]
[UpdateTracker:9787791] Update Tracker - [Pathway:1810476] RIP-mediated NFkB activation via ZBP1 - v44:[updateContainedRLE]
[UpdateTracker:9787762] Update Tracker - [Reaction:141159] TNF-mediated dimerization of procaspase-8 - v44:[addInput, addLiteratureReference, add_removeOutput, modifyText]
[UpdateTracker:9787820] Update Tracker - [Reaction:198845] CYB5A:heme reduces Asc.- to AscH- - v44:[modifyText]
[UpdateTracker:9788030] Update Tracker - [Pathway:111469] SMAC, XIAP-regulated apoptotic response - v44:[updateIndirectRLE]
[UpdateTracker:9787800] Update Tracker - [Pathway:204626] Hypusine synthesis from eIF5A-lysine - v44:[updateContainedRLE]
[UpdateTracker:9787949] Update Tracker - [Reaction:83656] TNF:TNFR1 binds TRADD, TRAF2 and RIPK1 - v44:[addRegulator, add_removeInput]
[UpdateTracker:9787528] Update Tracker - [Reaction:2396606] Recruitment of PLC-gamma to SLP-76 and p-5Y-LAT - v44:[addLiteratureReference, add_removeInput, modifyText]
[UpdateTracker:9787613] Update Tracker - [Pathway:139915] Activation of PUMA and translocation to mitochondria - v44:[updateContainedRLE]
[UpdateTracker:9787855] Update Tracker - [Pathway:445144] Signal transduction by L1 - v44:[updateContainedRLE]
[UpdateTracker:9787580] Update Tracker - [Reaction:180725] Rev associates with B23 - v44:[add_removeInput]
[UpdateTracker:9787772] Update Tracker - [Reaction:372697] Crk binding to p130cas - v44:[add_removeInput]
[UpdateTracker:9787633] Update Tracker - [Pathway:202424] Downstream TCR signaling - v44:[updateContainedRLE]
[UpdateTracker:9787836] Update Tracker - [Reaction:198732] STAT3 activation - v44:[add_removeInput, add_removeOutput]
[UpdateTracker:9787783] Update Tracker - [Reaction:1980074] Ubiquitination of DLL/JAG ligands upon binding to NOTCH1 - v44:[modifyText]
[UpdateTracker:9787663] Update Tracker - [Reaction:196964] RFK:Mg2+ phosphorylates RIB - v44:[modifyText]
[UpdateTracker:9787797] Update Tracker - [Pathway:975155] MyD88 dependent cascade initiated on endosome - v44:[updateIndirectRLE]
[UpdateTracker:9788048] Update Tracker - [Reaction:933531] Translocation of p-IRF7:p-IRF7 to nucleus - v44:[addRegulator]
[UpdateTracker:9787630] Update Tracker - [Reaction:180855] Translocation of Vpr to the mitochondria - v44:[add_removeInput, add_removeOutput]
[UpdateTracker:9787578] Update Tracker - [BlackBoxEvent:1592238] Expression of ALAS1 - v44:[modifyText]
[UpdateTracker:9787543] Update Tracker - [Pathway:111447] Activation of BAD and translocation to mitochondria - v44:[add_removeHasEvent, updateContainedRLE]
[UpdateTracker:9788040] Update Tracker - [Reaction:2424481] Recruitment of VAV and BTK to p-SLP-76 - v44:[addInput, modifyText]
[UpdateTracker:9788101] Update Tracker - [Pathway:111458] Formation of apoptosome - v44:[updateContainedRLE]
[UpdateTracker:9787915] Update Tracker - [Reaction:180905] Association of Vpr with ANT1 - v44:[add_removeInput]
[UpdateTracker:9788018] Update Tracker - [Reaction:170847] Phosphorylated SMAD2 and SMAD3 form a complex with SMAD4 - v44:[addLiteratureReference, modifyText]
[UpdateTracker:9788049] Update Tracker - [Pathway:167172] Transcription of the HIV genome - v44:[updateIndirectRLE]
[UpdateTracker:9787619] Update Tracker - [Reaction:111879] PIP2 hydrolysis - v44:[add_removeInput]
[UpdateTracker:9787846] Update Tracker - [Pathway:1474244] Extracellular matrix organization - v44:[addHasEvent, modifyText, updateContainedPathway, updateIndirectRLE]
[UpdateTracker:9787890] Update Tracker - [Reaction:199219] SLC5A6 cotransports extracellular Btn and 2xNa+ to cytosol - v44:[addLiteratureReference, modifyText]
[UpdateTracker:9787916] Update Tracker - [Pathway:110357] Displacement of DNA glycosylase by APEX1 - v44:[updateContainedRLE]
[UpdateTracker:9788031] Update Tracker - [Reaction:2424485] Release of p-PLCG1 - v44:[add_removeOutput]
[UpdateTracker:9788080] Update Tracker - [Reaction:2193065] Adam10 cleaves Notch2 - v44:[modifyText]
[UpdateTracker:9787741] Update Tracker - [Pathway:162909] Host Interactions of HIV factors - v44:[updateIndirectRLE]
[UpdateTracker:9787636] Update Tracker - [Reaction:173115] Formation of Pre-Integration Complex (PIC) - v44:[add_removeInput]
[UpdateTracker:9787979] Update Tracker - [Pathway:983695] Antigen activates B Cell Receptor (BCR) leading to generation of second messengers - v44:[updateContainedRLE]
[UpdateTracker:9787809] Update Tracker - [Pathway:381340] Transcriptional regulation of white adipocyte differentiation - v44:[updateContainedRLE]
[UpdateTracker:9787629] Update Tracker - [Pathway:354192] Integrin signaling - v44:[updateIndirectRLE]
[UpdateTracker:9787579] Update Tracker - [Pathway:195399] VEGF binds to VEGFR leading to receptor dimerization - v44:[updateContainedRLE]
[UpdateTracker:9787565] Update Tracker - [Pathway:1430728] Metabolism - v44:[addHasEvent, updateContainedPathway]
[UpdateTracker:9787547] Update Tracker - [Pathway:75893] TNF signaling - v44:[updateContainedRLE]
[UpdateTracker:9787888] Update Tracker - [Pathway:212676] Dopamine Neurotransmitter Release Cycle - v44:[updateContainedRLE]
[UpdateTracker:9787542] Update Tracker - [Reaction:374669] L1 binds NRP1 - v44:[add_removeInput]
[UpdateTracker:9787906] Update Tracker - [Reaction:975608] LRAT esterifies RBP2:atROL and FACYLs to atREs - v44:[add_removeInput, modifyText]
[UpdateTracker:9787617] Update Tracker - [Pathway:1461957] Beta defensins - v44:[updateContainedRLE]
[UpdateTracker:9787699] Update Tracker - [Reaction:114254] CYCS binds to APAF1 - v44:[modifyText]
[UpdateTracker:9787784] Update Tracker - [Reaction:1834951] IFI16 binds cytosolic dsDNA - v44:[add_removeInput]
[UpdateTracker:9787985] Update Tracker - [Pathway:109606] Intrinsic Pathway for Apoptosis - v44:[updateContainedPathway, updateIndirectRLE]
[UpdateTracker:9787753] Update Tracker - [Reaction:2424486] Phosphorylation and activation of VAV2/VAV3 by SYK - v44:[removeInput]
[UpdateTracker:9788000] Update Tracker - [Pathway:168276] NS1 Mediated Effects on Host Pathways - v44:[updateIndirectRLE]
[UpdateTracker:9787913] Update Tracker - [Reaction:170861] Dimeric TGF-beta-1 binds to the receptor - v44:[addLiteratureReference, add_removeInput, modifyText]
[UpdateTracker:9787754] Update Tracker - [Reaction:936897] ATP1A:ATP1B:FXYD exchanges 3Na+ for 2K+ - v44:[add_removeLiteratureReference, modifyText]
[UpdateTracker:9787861] Update Tracker - [Reaction:1912393] MAML in complex with NICD1 recruits CDK8 - v44:[modifyText]
[UpdateTracker:9787959] Update Tracker - [Reaction:157632] Complex of NOTCH1 with its ligand is cleaved to produce NEXT1 - v44:[modifyText]
[UpdateTracker:9787721] Update Tracker - [Reaction:549279] OCT2 mediates tubular uptake of organic cations in the kidney - v44:[add_removeLiteratureReference]
[UpdateTracker:9788062] Update Tracker - [Pathway:164944] Nef and signal transduction - v44:[updateContainedRLE]
[UpdateTracker:9787586] Update Tracker - [Pathway:975110] TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling - v44:[updateContainedRLE]
[UpdateTracker:9788096] Update Tracker - [Reaction:176517] SULTs transfer (SO4)2- group to PREG - v44:[modifyText]
[UpdateTracker:9787635] Update Tracker - [Reaction:549129] OCT1 transports organic cations into hepatic cells - v44:[add_removeLiteratureReference]
[UpdateTracker:9787775] Update Tracker - [Reaction:198813] GSTO dimers reduce DeHA to AscH- - v44:[modifyText]
[UpdateTracker:9787749] Update Tracker - [Reaction:175258] 2-LTR formation due to circularization of viral DNA - v44:[add_removeOutput]
[UpdateTracker:9788066] Update Tracker - [Reaction:168166] NF-kappa-B complex is transported from cytosol to nucleus - v44:[addRegulator]
[UpdateTracker:9787532] Update Tracker - [Pathway:936837] Ion transport by P-type ATPases - v44:[updateContainedRLE]
[UpdateTracker:9787956] Update Tracker - [Reaction:203662] eNOS:Caveolin-1:NOSTRIN complex binds dynamin-2 - v44:[add_removeInput]
[UpdateTracker:9788003] Update Tracker - [Reaction:139905] Translocation of activated BAD protein to mitochondria - v44:[addLiteratureReference, modifyText]
[UpdateTracker:9787684] Update Tracker - [Reaction:418309] ATP2B1-4 transport cytosolic Ca2+ to extracellular region - v44:[modifyText]
[UpdateTracker:9787540] Update Tracker - [Pathway:166058] MyD88:MAL(TIRAP) cascade initiated on plasma membrane - v44:[updateIndirectRLE]
[UpdateTracker:9787664] Update Tracker - [Reaction:195408] NRP-1 forms a ternary complex with VEGF165 and VEGFR1 - v44:[add_removeInput]
[UpdateTracker:9787862] Update Tracker - [Pathway:164952] The role of Nef in HIV-1 replication and disease pathogenesis - v44:[updateIndirectRLE]
[UpdateTracker:9787596] Update Tracker - [Reaction:420595] Necl-2:Nectin 3 trans heterodimer interaction - v44:[add_removeInput]
[UpdateTracker:9788083] Update Tracker - [Pathway:211733] Regulation of activated PAK-2p34 by proteasome mediated degradation - v44:[updateContainedRLE]
[UpdateTracker:9787859] Update Tracker - [Pathway:416476] G alpha (q) signalling events - v44:[updateContainedRLE]
[UpdateTracker:9787606] Update Tracker - [Pathway:68882] Mitotic Anaphase - v44:[addHasEvent, updateIndirectRLE]
[UpdateTracker:9787823] Update Tracker - [Reaction:205112] gamma-secretase cleaves p75NTR, releasing NRIF and TRAF6 - v44:[add_removeOutput]
[UpdateTracker:9787673] Update Tracker - [Reaction:975449] GABRR pentamers:GABA transports extracellular Cl- to cytosol - v44:[modifyText]
[UpdateTracker:9788082] Update Tracker - [Pathway:162582] Signal Transduction - v44:[addHasEvent, updateContainedPathway, updateIndirectRLE]
[UpdateTracker:9787853] Update Tracker - [Pathway:350054] Notch-HLH transcription pathway - v44:[updateContainedRLE]
[UpdateTracker:9788069] Update Tracker - [Pathway:167160] RNA Pol II CTD phosphorylation and interaction with CE during HIV infection - v44:[updateContainedRLE]
[UpdateTracker:9787743] Update Tracker - [Pathway:382551] Transport of small molecules - v44:[updateContainedPathway]
[UpdateTracker:9787973] Update Tracker - [Reaction:2395801] Phosphorylation of LAT by p-SYK - v44:[modifyText]
[UpdateTracker:9787817] Update Tracker - [Reaction:420584] Necl-1:Nectin 3 trans heterodimer interaction - v44:[add_removeInput]
[UpdateTracker:9787526] Update Tracker - [Reaction:114419] Dissociation of Caspase-3 from DIABLO:XIAP:Caspase-3 - v44:[addLiteratureReference, modifyText]
[UpdateTracker:9787981] Update Tracker - [Reaction:205075] JNK phosphorylates BIM, BAD and other targets - v44:[add_removeInput, add_removeOutput]
[UpdateTracker:9787534] Update Tracker - [Pathway:2424491] DAP12 signaling - v44:[updateContainedRLE]
[UpdateTracker:9787587] Update Tracker - [Reaction:2396594] Phosphorylation of SLP-76 by p-SYK - v44:[add_removeInput, modifyText]
[UpdateTracker:9787827] Update Tracker - [Reaction:196761] 2xTPK1:Mg2+ phosphorylates THMN - v44:[modifyText]
[UpdateTracker:9787917] Update Tracker - [Pathway:381676] Glucagon-like Peptide-1 (GLP1) regulates insulin secretion - v44:[updateContainedRLE]
[UpdateTracker:9787582] Update Tracker - [Reaction:1471354] HNP1-3 bind gp120 - v44:[add_removeInput]
[UpdateTracker:9787950] Update Tracker - [Reaction:194311] VEGFA,B,PLGF bind to VEGFR1 leading to receptor dimerization - v44:[add_removeInput]
[UpdateTracker:9788072] Update Tracker - [Pathway:380108] Chemokine receptors bind chemokines - v44:[updateContainedRLE]
[UpdateTracker:9787764] Update Tracker - [Pathway:72086] mRNA Capping - v44:[updateContainedRLE]
[UpdateTracker:9788050] Update Tracker - [Pathway:196836] Vitamin C (ascorbate) metabolism - v44:[updateContainedRLE]
[UpdateTracker:9787998] Update Tracker - [Reaction:445083] CHL1 interacts with NRP1 - v44:[add_removeInput]
[UpdateTracker:9787602] Update Tracker - [BlackBoxEvent:139913] TP53 stimulates BBC3 (PUMA) expression - v44:[modifyText]
[UpdateTracker:9788007] Update Tracker - [BlackBoxEvent:212920] Ubiquitination of PAK-2p34 - v44:[add_removeOutput, modifyText]
[UpdateTracker:9787799] Update Tracker - [Pathway:193697] p75NTR regulates axonogenesis - v44:[updateIndirectRLE]
[UpdateTracker:9787670] Update Tracker - [Pathway:1614635] Sulfur amino acid metabolism - v44:[updateContainedRLE]
[UpdateTracker:9787924] Update Tracker - [Pathway:212436] Generic Transcription Pathway - v44:[updateContainedPathway, updateContainedRLE, updateIndirectRLE]
[UpdateTracker:9787648] Update Tracker - [Pathway:169911] Regulation of Apoptosis - v44:[updateIndirectRLE]
[UpdateTracker:9788057] Update Tracker - [Pathway:111465] Apoptotic cleavage of cellular proteins - v44:[updateContainedRLE]
[UpdateTracker:9787653] Update Tracker - [Pathway:176033] Interactions of Vpr with host cellular proteins - v44:[updateIndirectRLE]
[UpdateTracker:9787616] Update Tracker - [Reaction:114563] Collagen type I binds integrin alpha1beta1, alpha2beta1, alpha10beta1 - v44:[add_removeInput]
[UpdateTracker:9787609] Update Tracker - [Reaction:165162] Phosphorylation of TSC2 by PKB - v44:[add_removeInput]
[UpdateTracker:9787919] Update Tracker - [Pathway:196780] Biotin transport and metabolism - v44:[modifyText, updateContainedRLE]
[UpdateTracker:9787798] Update Tracker - [Reaction:374248] Receptor CXCR3 binds ligands CXCL9 to 11 - v44:[add_removeInput]
[UpdateTracker:9787538] Update Tracker - [Pathway:170984] ARMS-mediated activation - v44:[updateContainedRLE]
[UpdateTracker:9787623] Update Tracker - [Reaction:74448] Calcium binds calmodulin - v44:[modifyText]
[UpdateTracker:9788089] Update Tracker - [BlackBoxEvent:1254392] PGR gene expression is stimulated by ERBB4s80:ESR1:estrogen - v44:[add_removeOutput]
[UpdateTracker:9787789] Update Tracker - [Reaction:195251] Assembly of the destruction complex - v44:[add_removeInput]
[UpdateTracker:9788108] Update Tracker - [Pathway:1500931] Cell-Cell communication - v44:[updateIndirectRLE]
[UpdateTracker:9788065] Update Tracker - [Pathway:445989] TAK1-dependent IKK and NF-kappa-B activation - v44:[updateContainedRLE]
[UpdateTracker:9788058] Update Tracker - [Pathway:156584] Cytosolic sulfonation of small molecules - v44:[updateContainedRLE]
[UpdateTracker:9787662] Update Tracker - [Pathway:210747] Regulation of gene expression in early pancreatic precursor cells - v44:[updateContainedRLE]
[UpdateTracker:9787559] Update Tracker - [Pathway:114604] GPVI-mediated activation cascade - v44:[updateContainedRLE]
[UpdateTracker:9788095] Update Tracker - [Reaction:165027] Rev molecules assemble onto the RRE RNA sequence through their ARM sequence - v44:[add_removeInput]
[UpdateTracker:9787677] Update Tracker - [Pathway:181429] Serotonin Neurotransmitter Release Cycle - v44:[updateContainedRLE]
[UpdateTracker:9787652] Update Tracker - [Pathway:168256] Immune System - v44:[updateContainedPathway]
[UpdateTracker:9787942] Update Tracker - [Reaction:167153] SPT5 subunit of Pol II binds the RNA triphosphatase (RTP) - v44:[add_removeInput]
[UpdateTracker:9787733] Update Tracker - [Reaction:975389] GLRA:GLRB:Gly transports extracellular Cl- to cytosol - v44:[modifyText]
[UpdateTracker:9787819] Update Tracker - [Reaction:382613] PEX-19 docks ABCD1/D2/D3 to peroximal membrane - v44:[add_removeOutput]
[UpdateTracker:9787758] Update Tracker - [BlackBoxEvent:211467] HNF1A-dependent synthesis of HNF4G protein - v44:[add_removeRegulator]
[UpdateTracker:9787787] Update Tracker - [BlackBoxEvent:139952] Caspase-8 processing in the DISC - v44:[addCatalystActivity, addLiteratureReference, addRegulator, add_removeInput, add_removeOutput, modifyText]
[UpdateTracker:9787649] Update Tracker - [Reaction:199062] KLRC1:KLRD1 heterodimer interacts with HLA-E - v44:[add_removeInput]
[UpdateTracker:9787865] Update Tracker - [Pathway:210746] Regulation of gene expression in endocrine-committed (NEUROG3+) progenitor cells - v44:[updateContainedRLE]
[UpdateTracker:9787931] Update Tracker - [Reaction:202723] Integrin alpha5beta1 binds FN1 dimer - v44:[modifyText]
[UpdateTracker:9787746] Update Tracker - [Pathway:264876] Insulin processing - v44:[updateContainedRLE]
[UpdateTracker:9787567] Update Tracker - [Reaction:196840] 3xPPCDC:3FMN decarboxylates PPC - v44:[modifyText]
[UpdateTracker:9787525] Update Tracker - [Pathway:167246] Tat-mediated elongation of the HIV-1 transcript - v44:[updateIndirectRLE]
[UpdateTracker:9787972] Update Tracker - [Pathway:187042] TRKA activation by NGF - v44:[updateContainedRLE]
[UpdateTracker:9787643] Update Tracker - [Pathway:1280218] Adaptive Immune System - v44:[updateIndirectRLE]
[UpdateTracker:9787839] Update Tracker - [Pathway:1834941] STING mediated induction of host immune responses - v44:[updateContainedRLE]
[UpdateTracker:9787577] Update Tracker - [Reaction:180736] Disassembly of the Rev-importin beta-B23:Ran-GTP complex - v44:[add_removeOutput]
[UpdateTracker:9788079] Update Tracker - [Pathway:182218] Nef Mediated CD8 Down-regulation - v44:[updateContainedRLE]
[UpdateTracker:9787568] Update Tracker - [Reaction:200952] Nef binds a ternary complex comprising DOCK2 guanine nucleotide exchange factor for small Rho-family GTPase Rac, its cofactor ELMO1, and Rac, and activates Rac through this interaction - v44:[add_removeInput]
[UpdateTracker:9787737] Update Tracker - [Reaction:157629] NOTCH2-ligand complex is cleaved to produce NEXT2 - v44:[add_removeInput, modifyText]
[UpdateTracker:9787785] Update Tracker - [Reaction:196955] 2xENPP1 hydrolyzes FAD to FMN - v44:[modifyText]
[UpdateTracker:9787961] Update Tracker - [Reaction:398193] PLC beta-mediated PIP2 hydrolysis - v44:[add_removeInput]
[UpdateTracker:9788005] Update Tracker - [Pathway:1428517] The citric acid (TCA) cycle and respiratory electron transport - v44:[updateContainedPathway]
[UpdateTracker:9787776] Update Tracker - [Reaction:399998] Activated Phospholipase C beta-1 hydrolyzes 1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate - v44:[add_removeInput]
[UpdateTracker:9788094] Update Tracker - [Pathway:69416] Dimerization of procaspase-8 - v44:[addLiteratureReference, modifyText, updateContainedRLE]
[UpdateTracker:9787581] Update Tracker - [Pathway:975138] TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation - v44:[updateIndirectRLE]
[UpdateTracker:9787657] Update Tracker - [Pathway:75158] TRAIL signaling - v44:[updateContainedRLE]
[UpdateTracker:9787750] Update Tracker - [Pathway:164843] 2-LTR circle formation - v44:[updateContainedRLE]
[UpdateTracker:9787573] Update Tracker - [Reaction:190519] Internalization of gap junction plaques - v44:[add_removeInput]
[UpdateTracker:9788114] Update Tracker - [Reaction:399942] Plexin-A1-4 binds NRP1 - v44:[add_removeInput]
[UpdateTracker:9787786] Update Tracker - [Pathway:418360] Platelet calcium homeostasis - v44:[updateIndirectRLE]
[UpdateTracker:9788025] Update Tracker - [Reaction:422021] PCSK1 hydrolyzes acyl Proghrelin to acyl Ghrelin - v44:[add_removeCatalystActivity]
[UpdateTracker:9787773] Update Tracker - [BlackBoxEvent:140221] Transactivation of BBC3 (PUMA) by E2F1 - v44:[modifyText]
[UpdateTracker:9787993] Update Tracker - [Pathway:2173789] TGF-beta receptor signaling activates SMADs - v44:[updateContainedPathway, updateContainedRLE, updateIndirectRLE]
[UpdateTracker:9787971] Update Tracker - [Reaction:196754] COASY transfers an adenylyl group from ATP to PPANT - v44:[modifyText]
[UpdateTracker:9787883] Update Tracker - [Pathway:1834949] Cytosolic sensors of pathogen-associated DNA - v44:[updateIndirectRLE]
[UpdateTracker:9787705] Update Tracker - [Reaction:382052] p130Cas and C3G bind PDGFR bound Crk - v44:[add_removeInput]
[UpdateTracker:9787680] Update Tracker - [Pathway:203641] NOSTRIN mediated eNOS trafficking - v44:[updateContainedRLE]
[UpdateTracker:9787947] Update Tracker - [Pathway:186797] Signaling by PDGF - v44:[updateIndirectRLE]
[UpdateTracker:9787882] Update Tracker - [Pathway:453274] Mitotic G2-G2/M phases - v44:[updateContainedPathway]
[UpdateTracker:9787885] Update Tracker - [Reaction:374251] DARC is a non-specific receptor for many chemokines - v44:[add_removeInput]
[UpdateTracker:9787944] Update Tracker - [Pathway:180746] Nuclear import of Rev protein - v44:[updateContainedRLE]
[UpdateTracker:9787804] Update Tracker - [Reaction:2468039] Acetylation of SMC3 subunit of chromosomal arm associated cohesin by ESCO1 or ESCO2 - v44:[addLiteratureReference, modifyText]
[UpdateTracker:9787969] Update Tracker - [Pathway:114452] Activation of BH3-only proteins - v44:[updateContainedPathway, updateIndirectRLE]
[UpdateTracker:9787704] Update Tracker - [Pathway:964975] Vitamins B6 activation to pyridoxal phosphate - v44:[updateContainedRLE]
[UpdateTracker:9788038] Update Tracker - [Pathway:139910] Activation of BMF and translocation to mitochondria - v44:[updateContainedRLE]
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