Reactome Pathway Database

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loss_of_function of BRCA2 mutants (RAD51 binding):SEM1 [nucleoplasm] Show undefined attributes

created [InstanceEdit:9763401] Orlic-Milacic, Marija, 2022年02月02日

dbId 9763399

diseaseEntity [Complex:R-HSA-9763400] BRCA2 mutants (RAD51 binding):SEM1 [nucleoplasm]

displayName loss_of_function of BRCA2 mutants (RAD51 binding):SEM1 [nucleoplasm]

functionalStatus

[FunctionalStatus:2317386] loss_of_function via missense_variant

modified [InstanceEdit:9768008] Orlic-Milacic, Marija, 2022年03月02日

normalEntity [Complex:R-HSA-9763139] p-T3387-BRCA2:SEM1 [nucleoplasm]

schemaClass EntityFunctionalStatus

Referrals

(entityFunctionalStatus)

[FailedReaction:R-HSA-9709571] BRCA2 mutants with BRC defects or a defect in the C-terminal RAD51 binding site do not bind RAD51

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