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gain_of_function of p-ERBB2 KD mutants:NRG1/NRG2:p-10Y-ERBB3:PI3K [plasma membrane] Show undefined attributes

created [InstanceEdit:9664667] Orlic-Milacic, Marija, 2019年10月26日

dbId 9664668

diseaseEntity [Complex:R-HSA-9664654] p-ERBB2 KD mutants:NRG1/NRG2:p-10Y-ERBB3:PI3K [plasma membrane]

displayName gain_of_function of p-ERBB2 KD mutants:NRG1/NRG2:p-10Y-ERBB3:PI3K [plasma membrane]

functionalStatus

[FunctionalStatus:2362351] gain_of_function via non_conservative_missense_variant

normalEntity [Complex:R-HSA-1250508] NRG1/2:p-ERBB3:p-ERBB2:PI3K [plasma membrane]

schemaClass EntityFunctionalStatus

Referrals

(entityFunctionalStatus)

[Reaction:R-HSA-9664664] PI3K bound to phosphorylated heterodimers of ERBB2 KD mutants and ERBB3 converts PIP2 to PIP3

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