Reactome Pathway Database

Schema > EntityFunctionalStatus > Entries

loss_of_function of BRCA1 mutants (BARD1 binding) [nucleoplasm] Show undefined attributes

created [InstanceEdit:9663212] Orlic-Milacic, Marija, 2019年09月27日

dbId 9663211

diseaseEntity [CandidateSet:R-HSA-9663193] BRCA1 mutants (BARD1 binding) [nucleoplasm]

displayName loss_of_function of BRCA1 mutants (BARD1 binding) [nucleoplasm]

functionalStatus

[FunctionalStatus:2317386] loss_of_function via missense_variant

normalEntity [EntityWithAccessionedSequence:R-HSA-50949] BRCA1 [nucleoplasm]

schemaClass EntityFunctionalStatus

Referrals

(entityFunctionalStatus)

[FailedReaction:R-HSA-9663194] Some pathogenic BRCA1 mutants do not bind BARD1

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