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9661413
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Bilirubin (BIL), the end product of heme catabolism, is take...
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Summation
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Bilirubin (BIL), the end product of heme catabolism, is taken up from the blood circulation into the liver. The organic anion transporting polypeptide SLCO1B1 (OATP, OATP2, OATPC, SLC21A6), localised on the basolateral (sinusoidal side) hepatocyte membrane, can mediate the uptake of BIL and various other lipophilic anions into the human liver (Konig et al. 2000, Cui et al. 2001).