Reactome Pathway Database

Schema > EntityFunctionalStatus > Entries

gain_of_function of p-5Y-EGFRvIII:PLCG1 [plasma membrane] Show undefined attributes

created [InstanceEdit:9630161] Orlic-Milacic, Marija, 2018年11月29日

dbId 9630162

diseaseEntity [Complex:R-HSA-5637698] p-5Y-EGFRvIII:PLCG1 [plasma membrane]

displayName gain_of_function of p-5Y-EGFRvIII:PLCG1 [plasma membrane]

functionalStatus

[FunctionalStatus:2632527] gain_of_function via inframe_deletion

modified [InstanceEdit:9631717] Wu, G, 2018年12月12日

normalEntity [Complex:R-HSA-212717] EGF-like ligands:p-6Y-EGFR:PLCG1 [plasma membrane]

schemaClass EntityFunctionalStatus

Referrals

(entityFunctionalStatus)

[Reaction:R-HSA-5637795] Phosphorylation of PLC-gamma 1 by p-EGFRvIII mutant

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