Reactome Pathway Database

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It is proposed that EPA-derived prostaglandin H3 (PGH3) unde... Show undefined attributes

created [InstanceEdit:9028211] Jassal, Bijay, 2017年11月07日

dbId 9028227

displayName It is proposed that EPA-derived prostaglandin H3 (PGH3) unde...

literatureReference

[LiteratureReference:9028217] The eicosapentaenoic acid metabolite 15-deoxy-?(12,14)-prostaglandin J3 increases adiponectin secretion by adipocytes partly via a PPAR?-dependent mechanism
[LiteratureReference:9028203] 15-deoxy-delta 12,14-prostaglandin J2. A prostaglandin D2 metabolite generated during inflammatory processes

modified [InstanceEdit:9028878] Jassal, Bijay, 2017年11月13日

schemaClass Summation

text It is proposed that EPA-derived prostaglandin H3 (PGH3) undergoes nonenzymatic dehydration to form prostaglandin J3 (PGJ3) (Fitzpatrick et al. 1983, Shibata et al. 2002). EPA supplementation to mice resulted in enhanced endogenous production of 15-deoxy-PGJ3 (15d-PGJ3), the final deoxy-product of EPA (Lefils-Lacourtablaise et al. 2013).

Referrals

(summation)

[Reaction:R-HSA-9028273] PGH3 spontaneously dehydrates to PGJ3

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