Reactome Pathway Database

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It is proposed that prostaglandin J3 (PGJ3) isomerises to pr... Show undefined attributes

created [InstanceEdit:9028211] Jassal, Bijay, 2017年11月07日

dbId 9028224

displayName It is proposed that prostaglandin J3 (PGJ3) isomerises to pr...

literatureReference

[LiteratureReference:9028203] 15-deoxy-delta 12,14-prostaglandin J2. A prostaglandin D2 metabolite generated during inflammatory processes
[LiteratureReference:9028229] Chemopreventive Effects of Dietary Eicosapentaenoic Acid Supplementation in Experimental Myeloid Leukemia
[LiteratureReference:9028296] ?12-prostaglandin J3, an omega-3 fatty acid-derived metabolite, selectively ablates leukemia stem cells in mice

modified [InstanceEdit:9955867] D'Eustachio, Peter, 2025年06月11日

schemaClass Summation

text It is proposed that prostaglandin J3 (PGJ3) isomerises to prostaglandin ?12-PGJ3 (?12-PGJ3) (Fitzpatrick et al. 1983, Shibata et al. 2002). EPA supplementation to mice resulted in enhanced endogenous production of ?12-PGJ3, which was found to possess chemoprotective activity against myleoid leukemia, ablating leukemia stem cells in mice (Hegde et al. 2011, Finch et al. 2015).

Referrals

(summation)

[BlackBoxEvent:R-HSA-9028263] PGJ3 isomerises to ?12-PGJ3

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