Reactome Pathway Database

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gain_of_function of mutant RAS:inactive BRAF:RAF1 [plasma membrane] Show undefined attributes

created [InstanceEdit:6802895] Rothfels, Karen, 2015年10月02日

dbId 6802894

diseaseEntity [Complex:R-HSA-6802674] mutant RAS:inactive BRAF:RAF1 [plasma membrane]

displayName gain_of_function of mutant RAS:inactive BRAF:RAF1 [plasma membrane]

functionalStatus

[FunctionalStatus:2362351] gain_of_function via non_conservative_missense_variant

modified [InstanceEdit:9631717] Wu, G, 2018年12月12日

normalEntity [Complex:R-HSA-5672733] p21 RAS:GTP:homo/heterodimerized RAF complex [plasma membrane]

schemaClass EntityFunctionalStatus

Referrals

(entityFunctionalStatus)

[Reaction:R-HSA-6802941] RAF is paradoxically phosphorylated downstream of kinase-inactive RAF

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