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Schema
>
FunctionalStatus
>
Entries
gain_of_function via inframe_insertion
Show undefined attributes
created
[InstanceEdit:5637716] Orlic-Milacic, Marija, 2014年11月12日
dbId
5637717
displayName
gain_of_function via inframe_insertion
functionalStatusType
[FunctionalStatusType:2426108] gain_of_function
schemaClass
FunctionalStatus
structuralVariant
[SequenceOntology:2318492] inframe_insertion
Referrals
(functionalStatus)
[EntityFunctionalStatus:5637727] gain_of_function of Ligand-responsive p-6Y-EGFR mutants:p-Y349,350-SHC1 [plasma membrane]
[EntityFunctionalStatus:5637720] gain_of_function of Ligand responsive p-6Y-EGFR mutants:p-Y349,350-SHC1:GRB2:SOS1 [plasma membrane]
[EntityFunctionalStatus:5637724] gain_of_function of Ligand-responsive p-6Y-EGFR mutants:CBL [plasma membrane]
[EntityFunctionalStatus:5637731] gain_of_function of Ligand-responsive p-6Y-EGFR mutants:SHC1 [plasma membrane]
[EntityFunctionalStatus:5637726] gain_of_function of Ligand-responsive p-6Y-EGFR mutants:PLCG1 [plasma membrane]
[EntityFunctionalStatus:5637719] gain_of_function of Ligand-responsive p-6Y-EGFR mutants:p-Y472,771,783,1254-PLCG1 [plasma membrane]
[EntityFunctionalStatus:5637730] gain_of_function of Ligand-responsive p-6Y-EGFR mutants:GRB2:SOS1 [plasma membrane]
[EntityFunctionalStatus:5637725] gain_of_function of Ligand-responsive p-6Y-EGFR mutants:GRB2:GAB1 [plasma membrane]
[EntityFunctionalStatus:5637722] gain_of_function of Ligand-responsive p-6Y-EGFR mutants:GRB2:GAB1:PI3K [plasma membrane]
[EntityFunctionalStatus:5637729] gain_of_function of EGF:Ligand-responsive EGFR mutants:HSP90:CDC37 [plasma membrane]
[EntityFunctionalStatus:5637721] gain_of_function of Ligand-responsive EGFR mutants:HSP90:CDC37 [plasma membrane]
[EntityFunctionalStatus:5637732] gain_of_function of Active dimers of ligand-responsive EGFR mutants [plasma membrane]
[EntityFunctionalStatus:5637728] gain_of_function of Ligand-responsive p-6Y-EGFR mutant dimers [plasma membrane]
[EntityFunctionalStatus:5637718] gain_of_function of Ligand-responsive EGFR mutants [plasma membrane]
[EntityFunctionalStatus:9664938] gain_of_function of p-6Y-ERBB2 KD mutants:EGF:p-6Y-EGFR:GRB2:GAB1:PI3K [plasma membrane]
[EntityFunctionalStatus:9665042] gain_of_function of p-6Y-ERBB2 KD mutants:EGF:p-6Y-EGFR:PLCG1 [plasma membrane]
[EntityFunctionalStatus:9665038] gain_of_function of p-6Y-ERBB2 KD mutants (PLCG1):EGF:p-6Y-EGFR [plasma membrane]
[EntityFunctionalStatus:9664931] gain_of_function of p-6Y-ERBB2 KD mutants:EGF:p-6Y-EGFR:GRB2:GAB1 [plasma membrane]
[EntityFunctionalStatus:9664989] gain_of_function of Phosphorylated heterodimers of ERBB2 KD mutants:p-Y349,Y350-SHC1:GRB2:SOS1 [plasma membrane]
[EntityFunctionalStatus:9664928] gain_of_function of p-6Y-ERBB2 KD mutants:EGF:p-6Y-EGFR [plasma membrane]
[EntityFunctionalStatus:9664980] gain_of_function of Phosphorylated heterodimers of ERBB2 KD mutants:p-Y349,Y350-SHC1 [plasma membrane]
[EntityFunctionalStatus:9664951] gain_of_function of Phosphorylated heterodimers of ERBB2 KD mutants [plasma membrane]
[EntityFunctionalStatus:9664971] gain_of_function of Phosphorylated heterodimers of ERBB2 KD mutants:SHC1 [plasma membrane]
[EntityFunctionalStatus:9664569] gain_of_function of ERBB2 KD mutants:ERBIN:HSP90:CDC37 [plasma membrane]
[EntityFunctionalStatus:9664607] gain_of_function of Heterodimers of ERBB2 KD mutants [plasma membrane]
[EntityFunctionalStatus:9664998] gain_of_function of p-6Y-ERBB2 KD mutants:EGF:p-6Y-EGFR [plasma membrane]
[EntityFunctionalStatus:9665011] gain_of_function of p-6Y-ERBB2 KD mutants:EGF:p-6Y-EGFR:GRB2:SOS1 [plasma membrane]
[EntityFunctionalStatus:9698200] gain_of_function of p-6Y FLT3 mutant dimers:GRB2:SOS1 [plasma membrane]
[EntityFunctionalStatus:9702062] gain_of_function of p-6Y FLT3 mutant dimers:GRB2:p-Y GAB2:PIK3R1 [plasma membrane]
[EntityFunctionalStatus:9698198] gain_of_function of p-6Y FLT3 mutant dimers:GRB2 [plasma membrane]
[EntityFunctionalStatus:9698194] gain_of_function of p-6Y FLT3 ITD mutant dimers:GRB2:p-Y GAB2:PTPN11:p-STAT5 [plasma membrane]
[EntityFunctionalStatus:9698190] gain_of_function of p-6Y FLT3 ITD mutant dimers:GRB2:p-Y GAB2:PTPN11 [plasma membrane]
[EntityFunctionalStatus:9698192] gain_of_function of p-6Y FLT3 ITD mutant dimers:GRB2:p-Y GAB2:PTPN11:STAT5 [plasma membrane]
[EntityFunctionalStatus:9698188] gain_of_function of p-6Y FLT3 mutant dimers:GRB2:p-Y GAB2 [plasma membrane]
[EntityFunctionalStatus:9695835] gain_of_function of FLT3 extracellular domain, kinase domain and juxtamembrane domain mutants [plasma membrane]
[EntityFunctionalStatus:9698197] gain_of_function of p-6Y FLT3 extracellular domain, kinase domain and juxtamembrane domain mutant dimers [plasma membrane]
[EntityFunctionalStatus:9698184] gain_of_function of p-6Y FLT3 mutant dimers:GRB2 [plasma membrane]
[EntityFunctionalStatus:9698186] gain_of_function of p-6Y FLT3 mutant dimers:GRB2:GAB2 [plasma membrane]
[EntityFunctionalStatus:9680251] gain_of_function of extracellular domain mutant dimers of KIT [plasma membrane]
[EntityFunctionalStatus:9680254] gain_of_function of extracellular domain mutants of KIT [plasma membrane]
[EntityFunctionalStatus:6802883] gain_of_function of high kinase activity BRAF mutants [cytosol]
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