Reactome Pathway Database

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Mucosa-associated lymphoid tissue lymphoma translocation pro... Show undefined attributes

created [InstanceEdit:5607612] Garapati, P V, 2014年07月14日

dbId 5607604

displayName Mucosa-associated lymphoid tissue lymphoma translocation pro...

literatureReference

[LiteratureReference:2685244] Identification of paracaspases and metacaspases: two ancient families of caspase-like proteins, one of which plays a key role in MALT lymphoma
[LiteratureReference:2685279] Bcl10 and MALT1, independent targets of chromosomal translocation in malt lymphoma, cooperate in a novel NF-kappa B signaling pathway

modified [InstanceEdit:5609981] Garapati, P V, 2014年07月18日

schemaClass Summation

text Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (MALT1) is the main downstream target of BCL10. MALT1 interacts directly with BCL10 and this interaction involves a short stretch of amino acids that follow the BCL10 CARD motif (amino acids 107?119 of human BCL10) and the two immunoglobulin-like domains of MALT1 (Uren et al. 2000, Lucas et al. 2001).

Referrals

(summation)

[Reaction:R-HSA-5607744] MALT1 binds BCL10

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