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2077409
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FP-1039 is an FGFR1c:Fc fragment that acts as a broad FGF- l...
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Summation
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FP-1039 is an FGFR1c:Fc fragment that acts as a broad FGF- ligand trap. Developed by FivePrime therapeutics (http://www.fiveprime.com/index.php?option=com_content&view=article&id=222&Itemid=153), FP-1039 is in Phase I clinical trials in solid malignancies and in Phase II trials in endometrial cancer patients carrying the FGFR2 S252W or P253R alleles.