Reactome Pathway Database

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3,7,24THCA (25(R) 3alpha,7alpha,24(S)-trihydroxy-5beta-chole... Show undefined attributes

created [InstanceEdit:193768] D'Eustachio, P, 2007年02月23日 20:48:08

dbId 193726

displayName 3,7,24THCA (25(R) 3alpha,7alpha,24(S)-trihydroxy-5beta-chole...

literatureReference

[LiteratureReference:193432] Participation of two members of the very long-chain acyl-CoA synthetase family in bile acid synthesis and recycling

modified [InstanceEdit:194078] D'Eustachio, P, 2007年03月08日 15:03:08

schemaClass Summation

text 3,7,24THCA (25(R) 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestanoate), coenzyme A, and ATP react to form the CoA conjugate of 3,7,24THCA, AMP, pyrophosphate and water. This cytosolic reaction is catalyzed by SLC27A5 (BACS). SLC27A2 (VLCS) also catalyzes this reaction; the relative contributions of the two enzymes to de novo bile acid synthesis in vivo are not certain (Mihalik et al. 2002).

Referrals

(summation)

[Reaction:R-HSA-193711] 3,7,24THCA is conjugated with Coenzyme A (SLC27A5 BACS)

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