Reactome Pathway Database

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After the second jump, elongation of the plus and minus stra... Show undefined attributes

created [InstanceEdit:177417] D'Eustachio, P, 2006年03月30日 15:26:43

dbId 177425

displayName After the second jump, elongation of the plus and minus stra...

literatureReference

[LiteratureReference:177418] Human immunodeficiency virus 1 reverse transcriptase. Template binding, processivity, strand displacement synthesis, and template switching.
[LiteratureReference:177446] Strand displacement activity of the human immunodeficiency virus type 1 reverse transcriptase heterodimer and its individual subunits
[LiteratureReference:182836] 'Binding, bending and bonding': polypurine tract-primed initiation of plus-strand DNA synthesis in human immunodeficiency virus

modified [InstanceEdit:188558] D'Eustachio, P, 2006年10月17日 19:40:04

schemaClass Summation

text After the second jump, elongation of the plus and minus strands continues. The elongation process requires strand displacement, which RT can mediate, at least in vitro (Huber et al. 1989; Hottiger et al. 1994; Rausch and Le Grice 2004). The final product is a blunt-ended linear duplex DNA with a discontinuity in its "plus" strand at the site of the cPPT sequence motif.

Referrals

(summation)

[Reaction:R-HSA-164505] Synthesis of full-length duplex viral DNA with a discontinuous plus strand

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