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February 21, 2025

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07/30/2025

Research Article

LeishTec vaccination disrupts vertical transmission of Leishmania infantum

Zoonotic canine leishmaniosis, caused by Leishmania infantum, is a fatal disease worldwide in both humans and the reservoir host, dogs. The primary route of transmission is via sand fly bite. Vertical, transplacental, transmission of L. infantum to offspring has been shown to be critical for maintenance of infection in both endemic and non-endemic areas. In the United States, canine leishmaniosis (CanL) is enzootic within hunting dog populations...

Image credit: Mufid Majnun, Unsplash

LeishTec vaccination disrupts vertical transmission of Leishmania infantum

Recently Published Articles

07/09/2025

Viewpoints

Large language models and their performance for the diagnosis of histoplasmosis

Progressive disseminated histoplasmosis remains a major but largely undiagnosed AIDS-defining opportunistic infection. Low awareness of the disease, its proteiform presentation and the lack of rapid diagnostic tools in most endemic areas still cause potentially fatal delays in antifungal treatment. This is particularly true in South and Central America where disease incidence is high but probably in Africa and Asia where it is suspected to be mostly overlooked...

Image credit: pntd.0013151

Large language models and their performance for the diagnosis of histoplasmosis

07/30/2025

Research Article

Seasonal change of Burkholderia pseudomallei in paddy field water strongly correlates with ambient temperature: A study in north-central Vietnam

Melioidosis, a fatal infectious disease caused by the environmental bacterium Burkholderia pseudomallei, is known to be associated with the rainy season. Although several attempts have been made to explain this phenomenon, data on the association between the presence of B. pseudomallei in...

Image credit: pntd.0013322

Seasonal change of Burkholderia pseudomallei in paddy field water strongly correlates with ambient temperature: A study in north-central Vietnam

07/07/2025

Research Article

Field evidence of Trypanosoma cruzi infection, diverse host use and invasion of human dwellings by the Chagas disease vector in Florida, USA

Triatomine bugs (Hemiptera, Reduviidae, Triatominae) are blood-sucking vectors of the protozoan parasite, Trypanosoma cruzi, which causes Chagas disease, a significant source of human morbidity and mortality in the Americas...

Field evidence of Trypanosoma cruzi infection, diverse host use and invasion of human dwellings by the Chagas disease vector in Florida, USA

Image credit: pntd.0012920

07/31/2025

Review

Comprehensive analysis of Toxoplasma gondii migration routes and tissue dissemination in the host

Toxoplasma gondii is a highly adaptable intracellular parasite capable of infecting a wide range of warm-blooded animals, including humans. Following the ingestion of cysts and oocysts, the parasites rapidly emerge and transmigrate through the bloodstream, initiating a complex infection process. Despite reports...

Comprehensive analysis of Toxoplasma gondii migration routes and tissue dissemination in the host

Image credit: pntd.0013369

07/23/2025

Research Article

The long-term persistence of the wMel strain in Rio de Janeiro is threatened by poor integrated vector management and bacterium fitness cost on Aedes aegypti

New tools and methods are currently under evaluation by the World Health Organization for preventing arbovirus transmission, such as dengue, Zika, and...

The long-term persistence of the wMel strain in Rio de Janeiro is threatened by poor integrated vector management and bacterium fitness cost on Aedes aegypti

Image credit: pntd.0013372

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PLOS Neglected Tropical Diseases | ISSN: 1935-2735 (online)

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