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Welcome to TumorPortal
Genes, Cancers, DNA Mutations & Annotations

Explore the pan-cancer dataset:

by Tumor Types »

by Genes »

by Figures »

Questions or comments? Please contact us.

Explore dataset by tumor types Show Annotation Activity

Click on a tumor type to see what genes are significantly mutated in it (and other details).

Acute myeloid leukemia

Chronic lymphocytic leukemia

Diffuse large B-cell lymphoma

Esophageal adenocarcinoma

Glioblastoma multiforme

Kidney clear cell

Lung adenocarcinoma

Lung squamous cell carcinoma

Medulloblastoma

Multiple myeloma

combined cohort

Explore dataset by Genes

Click on a gene name to see what tumor types it is significantly mutated in (and other details).

36% of all patients

14% of all patients

7% of all patients

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5% of all patients

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3% of all patients

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3% of all patients

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3% of all patients

3% of all patients

2% of all patients

2% of all patients

2% of all patients

Explore by Figures

Or browse clickable interactive versions of figures from the paper.

Figure 2: Genes in each tumor type

Figure 3: Tumor-type-specific and pan-cancer genes

Figure 5: Discovery power in each tumor type

Power Calculator

Figure S1: Background mutation frequencies across cancer

Figs1.thumbnail

Cite TumorPortal

Using this data? Please cite Lawrence et al. Nature (2014)

Annotation Activity & Updates

Variants

Variant ID	Owner	Date
XPO1 p.E571A	Yiwei Li	2020年05月11日 14:50 pm
KRAS p.G13D	chris mademlis	2016年12月08日 07:17 am
BRAF p.V600E	Cláudio Santos	2015年10月07日 07:35 am
SUFU p.S342N	2015年07月27日 02:14 am
TCFL5 p.K341N	Nuria Gironés	2015年06月19日 11:49 am
BRAF p.V600E	Amaro Taylor-Weiner	2015年01月07日 15:45 pm
RIT1 p.F82L	Alice Berger	2015年01月07日 15:35 pm
RIT1 p.M90I	Alice Berger	2015年01月07日 15:33 pm
PIK3R1 p.V662_splice	Eli Van Allen	2015年01月06日 16:34 pm

Genes

Symbol	Owner	Date

Recent Votes

Variant/Gene	Owner	Vote	Date
OSMR	Deepak Parashar		2019年07月19日 14:56 pm
PIK3R1	Eli Van Allen		2015年01月06日 16:35 pm
ERCC2	Eli Van Allen		2015年02月02日 11:37 am
BRAF p.V600E	Amaro Taylor-Weiner		2015年01月07日 15:45 pm
ERCC2	Eli Van Allen		2015年02月02日 11:37 am
PIK3R1	Eli Van Allen		2015年01月06日 16:35 pm
PIK3R1	Eli Van Allen		2015年01月06日 16:35 pm
RIT1 p.F82L	Alice Berger		2015年01月07日 15:35 pm
C6orf165	Andre Bernards		2015年01月07日 15:56 pm
PIK3R1 p.V662_splice	Eli Van Allen		2015年01月06日 16:34 pm
RIT1	Alice Berger		2015年01月07日 15:39 pm
RIT1 p.F82L	Alice Berger		2015年01月07日 15:35 pm
C6orf165	Andre Bernards		2015年01月07日 15:56 pm
BRAF p.V600E	Amaro Taylor-Weiner		2015年01月07日 15:45 pm
RIT1 p.F82L	Alice Berger		2015年01月07日 15:35 pm
C6orf165	Andre Bernards		2015年01月07日 15:56 pm
BRAF p.V600E	Amaro Taylor-Weiner		2015年01月07日 15:45 pm
PIK3R1 p.V662_splice	Eli Van Allen		2015年01月06日 16:34 pm
PIK3R1	Eli Van Allen		2015年01月06日 16:35 pm
PIK3R1 p.V662_splice	Eli Van Allen		2015年01月06日 16:34 pm

Most Active Variants

Variant ID	Annotations
BRAF p.V600E	2
SUFU p.S342N	1
RIT1 p.F82L	1
XPO1 p.E571A	1
RIT1 p.M90I	1
KRAS p.G13D	1
PIK3R1 p.V662_splice	1
TCFL5 p.K341N	1

Most Active Genes

Symbol	Annotations

Highest Rated Users

User	Aggregate Upvotes
Eli Van Allen	9
Alice Berger	4
Andre Bernards	3
Amaro Taylor-Weiner	3
Deepak Parashar	1
Lee Lawton	0
Eila Arich-Landkof	0
Michael Reich	0
Cancer Development	0
Jon Bistline	0
Jacopo De Santa	0
A Ghazani	0
Lea Starita	0
Jill Mesirov	0
Ted Liefeld	0
Joanne Kotz	0
Gad Getz	0
Michael Lawrence	0
Jonathan Bistline	0
Atanas Kamburov	0
Eejung Kim	0
Paul Savage	0
Eva Samal	0
June-Koo Lee	0
0
Srivatsan Raghavan	0
Ankita Singh	0
Julian Hess	0
Xin Lu	0
SEKHAR DURAISAMY	0
Rui Fang	0
Solip Park	0
Johan Lindberg	0
Samuel Freeman	0
Jianing Xu	0
Michael Sharpnack	0
Aayush Raman	0
Rodrigo Toledo	0
Jon Goldstein	0
Lihua Zou	0
Benjamin Drapkin	0
Xin Jin	0
Uri Ben-David	0
Susan Bullman	0
Bradley Murray	0
Juliann Shih	0
Matthew Oser	0
Andrew Cherniack	0
Joaquim Bellmunt	0
Alexandru Floares	0

Most Active Users

User	Annotations
Eli Van Allen	3
Alice Berger	3
Viswanathan Palanisamy	3
Tanasan Sirirat	2
Andrew Cherniack	2
2
Venkat Addala	1
Nilofer	1
Heesun Cheong	1
Shoshana Levy	1
Yiwei Li	1
shiv verma	1
Deepak Parashar	1
Kyosuke Mukae	1
Meiou Dai	1
Dinesh M G	1
LI-JIE LI	1
Amaro Taylor-Weiner	1
Andre Bernards	1
MARIA GIULIA MANZIONE	1
Shengfang Jin	1
Utsa Bhaduri	1
Marta Rodriguez Martinez	1
Hanna Sowar	1
Jeffery Chakedis	1
chris mademlis	1
Peiyong Guan	1
Nour Al deen	1
Guido Marcucci	1
Daniel Menendez	1
Agostino Lacroix	1
Rachel Frieman	1
Cláudio Santos	1
Michael Boettcher	1
Deepak Jha	1
1
ben benbenben	1
Nuria Gironés	1
Cyrus Hedvat	1
Vera Kaiser	1
Peter King	1
Lee Lawton	0
Uri Ben-David	0
Susan Bullman	0
Bradley Murray	0
Juliann Shih	0
Matthew Oser	0
Benjamin Drapkin	0
Joaquim Bellmunt	0
Alexandru Floares	0