Diagnostic Microbiology and Infectious Disease
Volume 88, Issue 3, July 2017, Pages 233-235
VirologyEvaluation of a commercially available Zika virus IgM ELISA: specificity in focus
Abstract
Zika virus (ZIKV), an emerging arbovirus , has become the center of attention since it was linked to congenital abnormalities. Given the overlapping clinical picture of ZIKV disease with other infectious diseases and as an exigent public health matter, timely and reliable diagnosis of ZIKV infection is crucial. We evaluated the performance of a commercially available NS1-based ZIKV IgM ELISA. Our results showed suboptimal sensitivity within the first 5 days after onset while specificity remained robust.
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Financial support
This study was supported by Cadham Provincial Laboratory internal research funds.
Conflict of interest
None Declared.
Acknowledgement
We would like to thank the Viral Zoonoses section at National Microbiology Laboratory in Winnipeg, Canada for their kind help.
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