Multi-laboratory comparison of three commercially available Zika IgM enzyme-linked immunosorbent assays

ZIKV IgM kits from InBios, NovaTec and Euroimmun were compared in 3 separate labs.

InBios kit was most sensitive; Novatec and Euroimmun kits were most specific.

Concordance across the labs was high for both the NovaTec and Euroimmun IgM + IgG kits.

The NS1-based NovaTec and Euroimmun kits may be useful in confirmation of infection for a portion of patients and to reduce the number of PRNT’s required.