This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features!
Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

NIH NLM Logo
Log in
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Distribution of Japanese Encephalitis Virus, Japan and Southeast Asia, 2016-2018

Ryusei Kuwata et al. Emerg Infect Dis. 2020 Jan.

Abstract

During 2016-2018, we conducted surveillance for Japanese encephalitis virus (JEV) in mosquitoes and pigs in Japan, Thailand, the Philippines, and Indonesia. Phylogenetic analyses demonstrated that our isolates (genotypes Ia, Ib, III, IV) were related to JEV isolates obtained from the same regions many years ago. Indigenous JEV strains persist in Asia.

Keywords: Culex tritaeniorhynchus; GIII; GIV; Indonesia; Japan; Japanese encephalitis virus; Southeast Asia; Thailand; arbovirus; arthropodborne virus; epidemiology; meningitis/encephalitis; mosquitoborne disease; pig; surveillance; the Philippines; vector-borne infections; viruses; wild boar; zoonoses.

PubMed Disclaimer

Figures

Figure
Figure
Maximum-likelihood phylogeny of JEV isolates, Japan and Southeast Asia, 2016–2018 (circles), and reference isolates constructed on the basis of the envelope gene sequence (1,500 nt). A) Genotype Ia (GIa); B) genotype GIb; C) genotypes GIII and GIV; D) parent tree showing all genotypes. Tree was reconstructed by using MEGA6 (https://megasoftware.net) with 100 bootstraps under the general time-reversible model. JEVs isolated in Japan (blue), Thailand (green), the Philippines (yellow), and Indonesia (maroon) are indicated. In panels A–C, origin, year, and country of isolation are provided in parentheses; in panel D, DDBJ and GenBank accession numbers are provided. bo, bovine; eq, equine; hu, human; JEV, Japanese encephalitis virus; MQ, mosquito; NA, data not available; sw, swine; wb, wild boar.

References

    1. Arrigo NC, Weaver SC, Calisher CH. The taxonomy of arboviruses. In: Vasilakis N, Gubler DJ, editors. Arboviruses: molecular biology, evolution and control. Poole, UK: Caister Academic Press; 2016. p. 9–29.
    1. Campbell GL, Hills SL, Fischer M, Jacobson JA, Hoke CH, Hombach JM, et al. Estimated global incidence of Japanese encephalitis: a systematic review. Bull World Health Organ. 2011;89:766–74, 774A–774E. 10.2471/BLT.10.085233 - DOI - PMC - PubMed
    1. Samy AM, Alkishe AA, Thomas SM, Wang L, Zhang W. Mapping the potential distributions of etiological agent, vectors, and reservoirs of Japanese Encephalitis in Asia and Australia. Acta Trop. 2018;188:108–17. 10.1016/j.actatropica.2018年08月01日4 - DOI - PubMed
    1. Nabeshima T, Morita K. Phylogeographic analysis of the migration of Japanese encephalitis virus in Asia. Future Virol. 2010;5:343–54. 10.2217/fvl.10.21 - DOI
    1. Nga PT, del Carmen Parquet M, Cuong VD, Ma SP, Hasebe F, Inoue S, et al. Shift in Japanese encephalitis virus (JEV) genotype circulating in northern Vietnam: implications for frequent introductions of JEV from Southeast Asia to East Asia. J Gen Virol. 2004;85:1625–31. 10.1099/vir.0.79797-0 - DOI - PubMed

Publication types

LinkOut - more resources

Full text links
CDC-NCEZID full text link CDC-NCEZID Free PMC article
Cite

AltStyle によって変換されたページ (->オリジナル) /