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. 2018 Dec 3;11(1):616.
doi: 10.1186/s13071-018-3187-8.

Alternative insecticides for larval control of the dengue vector Aedes aegypti in Lao PDR: insecticide resistance and semi-field trial study

Affiliations

Alternative insecticides for larval control of the dengue vector Aedes aegypti in Lao PDR: insecticide resistance and semi-field trial study

Sébastien Marcombe et al. Parasit Vectors. .

Abstract

Background: The mosquito Aedes aegypti is the primary vector of several arboviruses, such as dengue, chikungunya and Zika, and represents a major public health problem in Southeast Asia. In Laos, where dengue is reemerging, several Ae. aegypti populations from the capital Vientiane have shown resistance to the organophosphate temephos, a commonly-used larvicide for public health interventions.

Methods: Here, we tested the insecticide susceptibility of a wild larval population of Ae. aegypti against Bacillus thuringiensis israelensis (Bti), diflubenzuron, pyriproxyfen and spinosad. Residual efficacies of Bti (VectobacWG®), diflubenzuron (Killmos®) and temephos (Abate®) were then evaluated under simulated field conditions against the wild Ae. aegypti population.

Results: The larval bioassays showed that the wild Ae. aegypti strain was moderately resistant to temephos and spinosad (resistance ratio, RR < 5) and fully susceptible to the other insecticides (RR = 1). The simulated field trial bioassays showed that all of the insecticides tested remained above the WHO acceptable larvicide threshold after 28 weeks.

Conclusions: These results suggest that Bti and diflubenzuron may be promising alternative larvicides for controlling dengue vectors in water-storage containers in Laos, especially against Ae. aegypti populations, in which resistance to temephos has been detected.

Keywords: Aedes aegypti; Bti; Dengue; Diflubenzuron; IGR; Laos; Pyriproxyfen; Spinosad; Temephos; Vector control.

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Conflict of interest statement

Ethics approval and consent to participate

No ethical authorization and consent to participate was needed for this study.

Consent for publication

Not applicable.

Competing interests

The authors declare that they have no competing interests.

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Figures

Fig. 1
Fig. 1
Emergence inhibition rates of Ae. aegypti mosquitoes (IPL strain) in the control and treated containers in semi-field trial
Fig. 2
Fig. 2
Average temperatures and pH in the control and treated containers

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