This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features!
Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

NIH NLM Logo
Log in
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2018 Nov 21;3(4):122.
doi: 10.3390/tropicalmed3040122.

Eliminating Neglected Tropical Diseases in Urban Areas: A Review of Challenges, Strategies and Research Directions for Successful Mass Drug Administration

Affiliations
Review

Eliminating Neglected Tropical Diseases in Urban Areas: A Review of Challenges, Strategies and Research Directions for Successful Mass Drug Administration

Alayne M Adams et al. Trop Med Infect Dis. .

Abstract

Since 1950, the global urban population grew from 746 million to almost 4 billion and is expected to reach 6.4 billion by mid-century. Almost 90% of this increase will take place in Asia and Africa and disproportionately in urban slums. In this context, concerns about the amplification of several neglected tropical diseases (NTDs) are warranted and efforts towards achieving effective mass drug administration (MDA) coverage become even more important. This narrative review considers the published literature on MDA implementation for specific NTDs and in-country experiences under the ENVISION and END in Africa projects to surface features of urban settings that challenge delivery strategies known to work in rural areas. Discussed under the thematics of governance, population heterogeneity, mobility and community trust in MDA, these features include weak public health infrastructure and programs, challenges related to engaging diverse and dynamic populations and the limited accessibility of certain urban settings such as slums. Although the core components of MDA programs for NTDs in urban settings are similar to those in rural areas, their delivery may need adjustment. Effective coverage of MDA in diverse urban populations can be supported by tailored approaches informed by mapping studies, research that identifies context-specific methods to increase MDA coverage and rigorous monitoring and evaluation.

Keywords: mass drug administration; neglected tropical diseases; urban health.

PubMed Disclaimer

Conflict of interest statement

The authors declare no conflict of interest. The opinions expressed in this article are the authors’ own and do not reflect the view of the Centers for Disease Control and Prevention, the Department of Health and Human Services, the US Agency for International Development (USAID) or the United States Government.

Figures

Figure 1
Figure 1
MDA coverage in the metropolitan area of Port-au-Prince, Haiti (2012–2018).
Figure 2
Figure 2
Program coverage for lymphatic filariasis in Bamako, Mali (2008–2016).

References

    1. United Nations, Department of Economic and Social Affairs, Population Division World Urbanization Prospects: The 2014 revision. [(accessed on 27 September 2018)]; Available online: https://esa.un.org/unpd/wup/publications/files/wup2014-highlights.pdf.
    1. Hotez P.J. Global urbanization and the neglected tropical diseases. PLoS Negl. Trop. Dis. 2017;11:e0005308. doi: 10.1371/journal.pntd.0005308. - DOI - PMC - PubMed
    1. Hotez P.J., Fenwick A., Savioli L., Molyneux D.H. Rescuing the bottom billion through control of neglected tropical diseases. Lancet. 2009;373:1570–1575. doi: 10.1016/S0140-6736(09)60233-6. - DOI - PubMed
    1. WHO Neglected Tropical Diseases. [(accessed on 26 September 2018)]; Available online: http://www.who.int/neglected_diseases/en/
    1. WHO/Department of Control of Neglected Tropical Diseases Crossing the Billion. Preventive chemotherapy for neglected tropical diseases. [(accessed on 17 April 2017)]; Available online: https://www.who.int/neglected_diseases/resources/9789240696471/en/

LinkOut - more resources

Full text links
MDPI full text link MDPI Free PMC article
Cite

AltStyle によって変換されたページ (->オリジナル) /