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. 2017 Dec 28;12(12):e0189879.
doi: 10.1371/journal.pone.0189879. eCollection 2017.

Chikungunya virus emergence in the Lao PDR, 2012-2013

Affiliations

Chikungunya virus emergence in the Lao PDR, 2012-2013

Somphavanh Somlor et al. PLoS One. .

Abstract

In May 2012, the first authenticated cases of active chikungunya virus infection were detected in Champasak Province, Southern Laos. Analysis of series of human samples and mosquito specimens collected during the outbreak and over the year that followed the emergence enabled the drawing up of a map of the progression of CHIKV and the establishment of a full genetic characterization of the virus.

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Conflict of interest statement

Competing Interests: All authors excepted Dr Philippe Buchy, declared no competing interests. Dr Philippe Buchy is currently an employee of GSK Vaccines but this position has no link with the work presented here. This does not alter the adherence of all authors to PLOS ONE policies on sharing data and materials.

Figures

Fig 1
Fig 1. Chikungunya virus study sites in 2012–2013.
1A) Entomologic surveillance sites in September 2012. Black triangles represent villages in Moonlapamok and Khong Districts. Red stars represent villages where mosquito larvae were sampled. 1B) Chikungunya virus IgM seroprevalence in villages in Moonlapamok District. 1C) Chikungunya virus IgM seroprevalence in villages in Khong District. Letters correspond to the villages’ code and numbers to the recorded seroprevalence level.
Fig 2
Fig 2. Main symptoms recorded declared by the volunteers during the retrospective seroprevalence study in 2013.
Fig 3
Fig 3. Phylogenetic tree of CHIKV strains based on E2-6K-E1 gene sequences, constructed using the maximum likelihood method.
Fig 4
Fig 4. Phylogenetic relationships of CHIKV strains from the Lao PDR based on complete genomes.
Phylogenetic tree constructed using the maximum likelihood method.

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