This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features!
Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

NIH NLM Logo
Log in
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2018 Jan;24(1):178-180.
doi: 10.3201/eid2401.171605. Epub 2018 Jan 17.

Molecular Characterization of Autochthonous Chikungunya Cluster in Latium Region, Italy

Molecular Characterization of Autochthonous Chikungunya Cluster in Latium Region, Italy

Licia Bordi et al. Emerg Infect Dis. 2018 Jan.

Abstract

We report partial molecular characterization of isolates from an autochthonous chikungunya virus cluster in Latium Region. E1 sequences from 3 patients differ substantially from sequences from the 2007 outbreak in Italy and lack the A226V substitution associated with increased viral fitness in the Aedes albopictus mosquito vector.

Keywords: A226V; CHIKV; Italy; Latium region; chikungunya virus; molecular characterization; viruses.

PubMed Disclaimer

References

    1. European Centre for Disease Prevention and Control. Clusters of autochthonous chikungunya cases in Italy, 14 September 2017. Stockholm: The Centre; 2017. [cited 2017 Oct 6]. https://ecdc.europa.eu/sites/portal/files/documents/14-Sep-2017-RRA-Chik...
    1. Rezza G, Nicoletti L, Angelini R, Romi R, Finarelli AC, Panning M, et al.; CHIKV study group. Infection with chikungunya virus in Italy: an outbreak in a temperate region. Lancet. 2007;370:1840–6. 10.1016/S0140-6736(07)61779-6 - DOI - PubMed
    1. World Health Organization. Disease outbreak news. Chikungunya—Italy. 2017. [cited 2017 Oct 10]. http:/www.who.int/csr/don/29-september-2017-chikungunya-italy/en
    1. Schuffenecker I, Iteman I, Michault A, Murri S, Frangeul L, Vaney MC, et al. Genome microevolution of chikungunya viruses causing the Indian Ocean outbreak. PLoS Med. 2006;3:e263. 10.1371/journal.pmed.0030263 - DOI - PMC - PubMed
    1. Tsetsarkin KA, Vanlandingham DL, McGee CE, Higgs S. A single mutation in chikungunya virus affects vector specificity and epidemic potential. PLoS Pathog. 2007;3:e201. 10.1371/journal.ppat.0030201 - DOI - PMC - PubMed

Publication types

LinkOut - more resources

Cite

AltStyle によって変換されたページ (->オリジナル) /