Evaluation of Simultaneous Transmission of Chikungunya Virus and Dengue Virus Type 2 in Infected Aedes aegypti and Aedes albopictus (Diptera: Culicidae)

doi:10.1093/jme/tjv017

. 2015 May;52(3):447-51.

doi: 10.1093/jme/tjv017. Epub 2015 Mar 15.

Evaluation of Simultaneous Transmission of Chikungunya Virus and Dengue Virus Type 2 in Infected Aedes aegypti and Aedes albopictus (Diptera: Culicidae)

J T Nuckols ¹, Y-J S Huang ², S Higgs ², A L Miller ³, R B Pyles ³, H M Spratt ⁴, K M Horne ⁵, D L Vanlandingham ⁶

Affiliations

¹ Joint Vaccine Acquisition Program, Medical Countermeasure Systems, United States Army, 1564 Freedman Drive, Fort Detrick, MD 21702.
² Biosecurity Research Institute, Kansas State University, 1041 Pat Roberts Hall, Manhattan KS 66506. Department of Diagnostic Medicine and Pathobiology, College of Veterinary Medicine, Kansas State University, L-222 Mosier Hall, Manhattan KS 66506.
³ Department of Pediatrics, University of Texas Medical Branch, 301 University Blvd., Galveston TX 77555-0436. Assay Development Services Division, Galveston National Laboratory, University of Texas Medical Branch, 301 University Blvd., Galveston TX 77555-0610.
⁴ Department of Preventative Medicine and Community Health, University of Texas Medical Branch, 301 University Blvd., Galveston TX 77555-1157.
⁵ Biosecurity Research Institute, Kansas State University, 1041 Pat Roberts Hall, Manhattan KS 66506.
⁶ Biosecurity Research Institute, Kansas State University, 1041 Pat Roberts Hall, Manhattan KS 66506. Department of Diagnostic Medicine and Pathobiology, College of Veterinary Medicine, Kansas State University, L-222 Mosier Hall, Manhattan KS 66506. dlvanlan@bri.ksu.edu.

PMID: 26334820
PMCID: PMC4581484
DOI: 10.1093/jme/tjv017

Evaluation of Simultaneous Transmission of Chikungunya Virus and Dengue Virus Type 2 in Infected Aedes aegypti and Aedes albopictus (Diptera: Culicidae)

J T Nuckols et al. J Med Entomol. 2015 May.

. 2015 May;52(3):447-51.

doi: 10.1093/jme/tjv017. Epub 2015 Mar 15.

Authors

J T Nuckols ¹, Y-J S Huang ², S Higgs ², A L Miller ³, R B Pyles ³, H M Spratt ⁴, K M Horne ⁵, D L Vanlandingham ⁶

Affiliations

¹ Joint Vaccine Acquisition Program, Medical Countermeasure Systems, United States Army, 1564 Freedman Drive, Fort Detrick, MD 21702.
² Biosecurity Research Institute, Kansas State University, 1041 Pat Roberts Hall, Manhattan KS 66506. Department of Diagnostic Medicine and Pathobiology, College of Veterinary Medicine, Kansas State University, L-222 Mosier Hall, Manhattan KS 66506.
³ Department of Pediatrics, University of Texas Medical Branch, 301 University Blvd., Galveston TX 77555-0436. Assay Development Services Division, Galveston National Laboratory, University of Texas Medical Branch, 301 University Blvd., Galveston TX 77555-0610.
⁴ Department of Preventative Medicine and Community Health, University of Texas Medical Branch, 301 University Blvd., Galveston TX 77555-1157.
⁵ Biosecurity Research Institute, Kansas State University, 1041 Pat Roberts Hall, Manhattan KS 66506.
⁶ Biosecurity Research Institute, Kansas State University, 1041 Pat Roberts Hall, Manhattan KS 66506. Department of Diagnostic Medicine and Pathobiology, College of Veterinary Medicine, Kansas State University, L-222 Mosier Hall, Manhattan KS 66506. dlvanlan@bri.ksu.edu.

PMID: 26334820
PMCID: PMC4581484
DOI: 10.1093/jme/tjv017

Abstract

The simultaneous transmission of chikungunya virus (CHIKV) and dengue viruses (DENV) has been a major public health concern because of their sympatric distribution and shared mosquito vectors. Groups of Aedes aegypti (L.) and Aedes albopictus (Skuse) were orally infected with 1.5 ×ばつ 10(5) PFU/ml of CHIKV and 3.2 ×ばつ 10(6) FFU/ml of DENV-2 simultaneously or separately in inverse orders and evaluated for dissemination and transmission by qRT-PCR. Simultaneous dissemination of both viruses was detected for all groups in Ae. aegypti and Ae. albopictus while cotransmission of CHIKV and DENV-2 only occurred at low rates after sequential but not simultaneous infection.

Keywords: Aedes aegypti; Aedes albopictus; chikungunya; dengue; transmission.

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References

1. Bagny L., Delatte H., Elissa N., Quilici S., Fontenille D. 2009a. Aedes (Diptera: Culicidae) vectors of arboviruses in Mayotte (Indian Ocean): distribution area and larval habitats. J. Med. Entomol. 46: 198–207. - PubMed
1. Bagny L., Delatte H., Quilici S., Fontenille D. 2009b. Progressive decrease in Aedes aegypti distribution in Reunion Island since the 1900s. J. Med. Entomol. 46: 1541–1545. - PubMed
1. Braks M. A., Honorio N. A., Lourencqo-De-Oliveira R., Juliano S. A., Lounibos L. P. 2003. Convergent habitat segregation of Aedes aegypti and Aedes albopictus (Diptera: Culicidae) in southeastern Brazil and Florida. J. Med. Entomol. 40: 785–794. - PubMed
1. Chahar H. S., Bharaj P., Dar L., Guleria R., Kabra S. K., Broor S. 2009. Co-infections with chikungunya virus and dengue virus in Delhi, India. Emerg. Infect. Dis. 15: 1077–1080. - PMC - PubMed
1. Chang S. F., Su C. L., Shu P. Y., Yang C. F., Liao T. L., Cheng C. H., Hu H. C., Huang J. H. 2010. Concurrent isolation of chikungunya virus and dengue virus from a patient with coinfection resulting from a trip to Singapore. J. Clin. Microbiol. 48: 4586–4589. - PMC - PubMed

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[1] Bagny L., Delatte H., Elissa N., Quilici S., Fontenille D. 2009a. Aedes (Diptera: Culicidae) vectors of arboviruses in Mayotte (Indian Ocean): distribution area and larval habitats. J. Med. Entomol. 46: 198–207. - PubMed

[2] Bagny L., Delatte H., Elissa N., Quilici S., Fontenille D. 2009a. Aedes (Diptera: Culicidae) vectors of arboviruses in Mayotte (Indian Ocean): distribution area and larval habitats. J. Med. Entomol. 46: 198–207. - PubMed

[3] Bagny L., Delatte H., Quilici S., Fontenille D. 2009b. Progressive decrease in Aedes aegypti distribution in Reunion Island since the 1900s. J. Med. Entomol. 46: 1541–1545. - PubMed

[4] Bagny L., Delatte H., Quilici S., Fontenille D. 2009b. Progressive decrease in Aedes aegypti distribution in Reunion Island since the 1900s. J. Med. Entomol. 46: 1541–1545. - PubMed

[5] Braks M. A., Honorio N. A., Lourencqo-De-Oliveira R., Juliano S. A., Lounibos L. P. 2003. Convergent habitat segregation of Aedes aegypti and Aedes albopictus (Diptera: Culicidae) in southeastern Brazil and Florida. J. Med. Entomol. 40: 785–794. - PubMed

[6] Braks M. A., Honorio N. A., Lourencqo-De-Oliveira R., Juliano S. A., Lounibos L. P. 2003. Convergent habitat segregation of Aedes aegypti and Aedes albopictus (Diptera: Culicidae) in southeastern Brazil and Florida. J. Med. Entomol. 40: 785–794. - PubMed

[7] Chahar H. S., Bharaj P., Dar L., Guleria R., Kabra S. K., Broor S. 2009. Co-infections with chikungunya virus and dengue virus in Delhi, India. Emerg. Infect. Dis. 15: 1077–1080. - PMC - PubMed

[8] Chahar H. S., Bharaj P., Dar L., Guleria R., Kabra S. K., Broor S. 2009. Co-infections with chikungunya virus and dengue virus in Delhi, India. Emerg. Infect. Dis. 15: 1077–1080. - PMC - PubMed

[9] Chang S. F., Su C. L., Shu P. Y., Yang C. F., Liao T. L., Cheng C. H., Hu H. C., Huang J. H. 2010. Concurrent isolation of chikungunya virus and dengue virus from a patient with coinfection resulting from a trip to Singapore. J. Clin. Microbiol. 48: 4586–4589. - PMC - PubMed

[10] Chang S. F., Su C. L., Shu P. Y., Yang C. F., Liao T. L., Cheng C. H., Hu H. C., Huang J. H. 2010. Concurrent isolation of chikungunya virus and dengue virus from a patient with coinfection resulting from a trip to Singapore. J. Clin. Microbiol. 48: 4586–4589. - PMC - PubMed

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Evaluation of Simultaneous Transmission of Chikungunya Virus and Dengue Virus Type 2 in Infected Aedes aegypti and Aedes albopictus (Diptera: Culicidae)

Affiliations

Evaluation of Simultaneous Transmission of Chikungunya Virus and Dengue Virus Type 2 in Infected Aedes aegypti and Aedes albopictus (Diptera: Culicidae)

Authors

Affiliations

Abstract

References

Publication types

MeSH terms

Grants and funding

LinkOut - more resources

Full Text Sources

Other Literature Sources

Medical