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. 2013 Apr;88(4):778-84.
doi: 10.4269/ajtmh.12-0442. Epub 2013 Feb 4.

Visceral leishmaniasis prevalence and associated risk factors in the saran district of Bihar, India, from 2009 to July of 2011

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Visceral leishmaniasis prevalence and associated risk factors in the saran district of Bihar, India, from 2009 to July of 2011

Diana Perry et al. Am J Trop Med Hyg. 2013 Apr.

Abstract

India is one of three countries that account for an estimated 300,000 of 500,000 cases of visceral leishmaniasis (VL) occurring annually. Bihar State is the most affected area of India, with more than 90% of the cases. Surveys were conducted in two villages within the Saran district of Bihar, India, from 2009 to July of 2011 to assess risk factors associated with VL. Forty-five cases were identified, and individuals were given an oral survey. The results indicated that men contracted the disease more than women (58%), and cases over the age of 21 years accounted for 42% of the total VL cases. April to June showed the highest number of new cases. Of 135 households surveyed for sleeping conditions, 95% reported sleeping outside, and 98% slept in beds. Proximity to VL cases was the greatest risk factor (cluster 1 relative risk = 11.89 and cluster 2 relative risk = 138.34). The VL case clustering observed in this study can be incorporated in disease prevention strategies to more efficiently and effectively target VL control efforts.

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Figures

Figure 1.
Figure 1.
Sex and age for cases of VL in 2009–2011 in both Rasulpur and Sutihaar. Percentages add up to 100% for each sex.
Figure 2.
Figure 2.
The total number as a percent of VL cases per quarter per year in Rasulpur (N = 27) and Sutihaar (N = 18) from 2009 to July of 2011. Each village's total cases adds to 100%.
Figure 3.
Figure 3.
Google Earth image of households and VL cases from 2009 to 2011 in Rasulpur. The red line around the village is the study area perimeter. Yellow houses (R1–23) represent case households, blue balloons represent non-case households, and the yellow pushpin marks the center of the case cluster (16/27 cases, RR = 11.89, P < 0.001).
Figure 4.
Figure 4.
Google Earth image of households and VL cases from 2009 to 2011 in Sutihaar. The red line around the village is the study area perimeter. Green houses (S1–14) represent case households, blue balloons represent non-case households, and the yellow pushpin represents the center point of the cluster radius (17/18 cases, RR = 138.34, P < 0.001).

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