Fatal nosocomial spread of Crimean-Congo hemorrhagic fever with very short incubation period
- PMID: 23269658
- PMCID: PMC3592527
- DOI: 10.4269/ajtmh.2012.12-0337
Fatal nosocomial spread of Crimean-Congo hemorrhagic fever with very short incubation period
Abstract
Crimean-Congo hemorrhagic fever is a tick-borne viral zoonosis with the potential of human-to-human transmission with case fatality rates from 3% to 50%. The incubation period depends on host, route of infection, and viral dose. Herein, we report a nosocomial spread of the disease in a hospital at Mashhad, northeastern Iran, with a very short incubation period for one of the secondary cases. The patient was a medical student who had a negligible contact with a Crimean-Congo hemorrhagic fever patient during his admission to the hospital. The time interval between the contact and the onset of symptoms was merely 20 hours. Unfortunately, he died within 1 week of exposure.
References
-
- Ergonul O. Clinical and pathologic features of Crimean-Congo Hemorrhagic Fever. In: Ergonul O, Whitehouse CA, editors. Crimean-Congo Hemorrhagic Fever: A Global Perspective. First edition. Dordrecht: Springer; 2007. pp. 207–220.
-
- World Health Organization Crimean-Congo Haemorrhagic Fever. 2001. http://www.who.int/mediacentre/factsheets/fs208/en Fact sheet No. 208. Revised November 2001. Available at. Accessed May 12, 2012.
-
- Pasteur Institute of Iran, Laboratory of Arboviruses and Viral Hemorrhagic Fevers Molecular Diagnosis of Crimean Congo Hemorrhagic Fever Virus by Qualitative Real-Time RT-PCR. http://www.arbo-zoo.net/_data/Qualitative_RT_PC_CCHF.doc Available at. Accessed May 12, 2012.
-
- Kaya A, Engin A, Güven AS, Içağasioğlu FD, Cevit O, Elaldi N, Gültürk A. Crimean-Congo hemorrhagic fever disease due to tick bite with very long incubation periods. Int J Infect Dis. 2011;15:e449–e452. - PubMed
-
- Burney MI, Ghafoor A, Saleen M, Webb PA, Casals J. Nosocomial outbreak of viral hemorrhagic fever caused by Crimean Hemorrhagic fever-Congo virus in Pakistan, January 1976. Am J Trop Med Hyg. 1980;29:941–947. - PubMed
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