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. 2012 Jun;18(6):982-5.
doi: 10.3201/eid1806.110948.

Molecular epidemiology of Laguna Negra virus, Mato Grosso State, Brazil

Affiliations

Molecular epidemiology of Laguna Negra virus, Mato Grosso State, Brazil

Elizabeth S Travassos da Rosa et al. Emerg Infect Dis. 2012 Jun.

Abstract

We associated Laguna Negra virus with hantavirus pulmonary syndrome in Mato Grosso State, Brazil, and a previously unidentified potential host, the Calomys callidus rodent. Genetic testing revealed homologous sequencing in specimens from 20 humans and 8 mice. Further epidemiologic studies may lead to control of HPS in Mato Grosso State.

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Figures

Figure 1
Figure 1
State of Mato Grosso, Brazil, indicating municipalities where hanta pulmonary syndrome cases occurred.
Figure 2
Figure 2
Phylogenetic comparison of the partial nucleotide sequences of nucleoprotein (N) gene of the small (S) RNA segment of different hantavirus strains from the Old World and New World by using the maximum-likelihood method and Bayesian analysis, with detail of the phylogenetic relationship between LNV strains isolated from humans and rodents in the state of Mato Grosso, Brazil. Bootstrap and Bayesian values (within parentheses) are shown for each respective knot. The arrows indicate the exact position of the values. Numbers within brackets correspond to the divergence between groups. Scale bar indicates 30% divergence of nucleotide sequences. APV, Alto Paraguay; ANAJV, Anajatuba, ANDV, Andes; BMJV, Andes Bermejo, NEMV, Andes Neembuco, LECV, Andes Lechiguanas; ORNV, Andes Oran; ARAV, Araraquara; BAYV, Bayou; BCCV, Black Creek Canal; CANOV, Cano Delgadito; CASV, Castelo dos Sonhos; CHOV, Choclo; EMCV, El Moro Canyon; HTNV, Hantaan; JUQV; Juquitiba-Araucaria; LNV, Laguna Negra; LSCV, Limestone Canyon; MULV, Muleshoe; NYV, New York; PRNV, Pergamino; PUUV, Puumala; RIOMV, Rio Mamoré; RIMEV, Rio Mearim; RIOSV, Rio Segundo; SEOV, Seoul; SNV, Sin Nombre; TULV, Tula.

References

    1. Nichol ST, Spiropoulou CE, Morzunov S, Rollin PE, Ksiazek TG, Feldmann H, et al. Genetic identification of a hantavirus associated with an outbreak of acute respiratory illness. Science. 1993;262:914–7. 10.1126/science.8235615 - DOI - PubMed
    1. Schmaljohn CS, Nichol ST. Bunyaviridae. In: Knipe DM, Griffin DE, Lamb RA, Strauss SE, Howley PM, Martin MA, et al., editors. Fields virology, 5th ed. Philadelphia: Lippincott Williams & Wilkins; 2007. p. 1741–89.
    1. Levis S, Murzonov S, Rowe J, Enria D, Pini N, Calderon G, et al. Genetic diversity and epidemiology of hantaviruses in Argentina. J Infect Dis. 1998;177:529–38. 10.1086/514221 - DOI - PubMed
    1. Padula PJ, Colavecchia SB, Martínez VP, Valle MO, Edelstein A, Miguel SDL, et al. Genetic diversity, distribution, and serological features of hantavirus infection in five countries in South America. J Clin Microbiol. 2000;38:3029–35. - PMC - PubMed
    1. Vincent MJ, Quiroz E, Gracia F, Sanchez AJ, Ksiazek TG, Kitsutani PT, et al. Hantavirus pulmonary syndrome in Panama: identification of novel hantaviruses and their likely reservoirs. Virology. 2000;277:14–9. 10.1006/viro.2000.0563 - DOI - PubMed

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