doi: 10.1186/1752-1947年2月12日3.
Successful treatment of Mycobacterium ulcerans osteomyelitis with minor surgical debridement and prolonged rifampicin and ciprofloxacin therapy: a case report
Affiliations
- PMID: 18439310
- PMCID: PMC2396654
- DOI: 10.1186/1752-1947年2月12日3
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Successful treatment of Mycobacterium ulcerans osteomyelitis with minor surgical debridement and prolonged rifampicin and ciprofloxacin therapy: a case report
Daniel P O'Brien et al.
J Med Case Rep.
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Abstract
Introduction: Treatment for osteomyelitis-complicating Mycobacterium ulcerans infection typically requires extensive surgery and even amputation, with no reported benefit from adjunctive antibiotics.
Case presentation: We report a case of an 87-year-old woman with M. ulcerans osteomyelitis that resolved following limited surgical debridement and 6 months of therapy with rifampicin and ciprofloxacin.
Conclusion: M. ulcerans osteomyelitis can be successfully treated with limited surgical debridement and adjunctive oral antibiotics.
Figures
A magnetic resonance imaging scan of the foot showing the destructive changes of osteomyelitis in the proximal first metatarsal bone and adjacent medial cuneiform bone.
References
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- O'Brien DP, Hughes AJ, Cheng AC, Henry MJ, Callan P, McDonald A, Holten I, Birrell M, Sowerby JM, Johnson PD, Athan E. Improved outcomes for Mycobacterium ulcerans infection with combined surgery and antibiotic therapy: findings from a south-eastern Australian case series. Med J Aust. 2007;186:58–61. - PubMed
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