Synaptic connections of the auditory nerve in cats: Relationship between endbulbs of held and spherical bushy cells

@article{Ryugo1991SynapticCO,
 title={Synaptic connections of the auditory nerve in cats: Relationship between endbulbs of held and spherical bushy cells},
 author={David K. Ryugo and Seishiro Sento},
 journal={Journal of Comparative Neurology},
 year={1991},
 volume={305},
 url={https://api.semanticscholar.org/CorpusID:21048653}
}
  • D. Ryugo S. Sento
  • Published in The Journal of comparative... 1 March 1991
  • Biology
  • Journal of Comparative Neurology
The data imply that endbulbs converging upon the cell body of a spherical bushy cell arise from fibers of the same SR group, a feature represented by systematic differences in endbulb silhouette perimeter without differences inEndbulbs of fibers having low spontaneous discharge rates.

180 Citations

Ultrastructural basis of synaptic transmission between endbulbs of Held and bushy cells in the rat cochlear nucleus
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Growth cones and structural variation of synaptic end‐bulbs in the cochlear nucleus of the adult cat brain
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The projections of intracellularly labeled auditory nerve fibers to the dorsal cochlear nucleus of cats
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Central projections of auditory nerve fibers of differing spontaneous rate, II: Posteroventral and dorsal cochlear nuclei
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A consideration of the average cell sizes, ANF swelling sizes and estimated numbers of ANFs of different CF and SR converging on each CN cell help explain some of the differences in response transformation associated with different cell types in the CN.
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41 References

Endbulbs of held and spherical bushy cells in cats: Morphological correlates with physiological properties
Single auditory nerve fibers of type I spiral ganglion cells in cats were electrophysiologically characterized by recording with micropipettes inserted into the axon and then labeled by intracellular injections of horseradish peroxidase through the same pipettes to describe structure‐function relationships for labeled endbulbs of Held and the somata of their postsynaptic spherical bushy cells.

The central projections of intracellularly labeled auditory nerve fibers in cats: an analysis of terminal morphology.
The axons of physiologically characterized spiral ganglion neurons (type I) were stained throughout their arborizations in the cochlear nucleus by the intracellular injection of horseradish peroxidase (HRP), consistent with the hypothesis that terminal swellings identifiable in the light microscope represent presynaptic endings.

Morphology of primary axosomatic endings in the anteroventral cochlear nucleus of the cat: A study of the endbulbs of Held
Three descriptive stages of endbulbs are conceived of as representing a developmental sequence in kittens 2, 5, 10, 20, and 45 days postnatal and adult cats and some implications of the proposed developmental sequence are discussed.

Central projections of intracellularly labeled auditory nerve fibers in cats: Morphometric correlations with physiological properties
The central arborizations and endings of type I spiral ganglion neurons were labeled with intracellular injections of horseradish peroxidase (HRP) after their characteristic frequency and spontaneous discharge rate were physiologically determined and the total number of branch points was correlated with total fiber length.

Relations between auditory nerve endings and cell types in the cat's anteroventral cochlear nucleus seen with the Golgi method and nomarski optics
Rapid Golgi impregnations of the ascending branches of the auditory nerve fibers and of the types of neurons in the anteroventral cochlear nucleus (AVCN) were studied to identify unimpregnated bushy and stellate perikarya.

The central projections of intracellularly labeled auditory nerve fibers in cats
The central projections of physiologically characterized auditory nerve fibers were studied in the cochlear nuclei of adult cats after intracellular staining with horseradish peroxidase (HRP), finding that spontaneous discharge rate is related to the complexity of the axon arbor.

The fine structure of nerve endings in the nucleus of the trapezoid body and the ventral cochlear nucleus.
Large, calyciform axonal endings were examined with the electron microscope in chinchillas, rats, and a cat after perfusion fixation with osmium tetroxide and were found to consist of elongated processes arising from myelinated axons and making multiple synaptic contacts with perikarya and dendrites.

The cochlear nerve in the cat: Topography, cochleotopy, and fiber spectrum
The topographical and cytological features of the cochlear nerve in normal adult cats were studied by microdissection, light microscopy, transmission and scanning electron microscopy to find the possible nature and origin of the three fiber categories.

Adaptations of synaptic form in an aberrant projection to the avian cochlear nucleus
The results support the idea that developmental interactions between synaptic partners can influence the form of the contact between the 2 neurons, and demonstrate that formation of persistent and functional synapses with NM neurons throughout development is not sufficient to induce any axon to assume the calycine form of a cochlear nerve endbulb.