Modulation of hERG K+ Channel Deactivation by Voltage Sensor Relaxation

@article{Shi2020ModulationOH,
 title={Modulation of hERG K+ Channel Deactivation by Voltage Sensor Relaxation},
 author={Yu Patrick Shi and Samrat Thouta and Tom W Claydon},
 journal={Frontiers in Pharmacology},
 year={2020},
 volume={11},
 url={https://api.semanticscholar.org/CorpusID:211534836}
}
This review discusses present knowledge and questions raised related to the voltage sensor relaxation mechanism in hERG channels and compares structure-function aspects of relaxation with those observed in related ion channels to highlight the insight that these studies provide into the control of hERG channel deactivation gating during their physiological functioning.

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