Release
pathway
brite
module
ko
genes
genome
compound
glycan
reaction
rclass
enzyme
(valid EC)
network
variant
disease
drug
dgroup
M
RM
<org>
ag
vg
vp
T0/T1
T4
Vtax
N
nt
116
2025/10
580
203
546
48
27,826
62,348,162
4,308
688,601
377
11,214
359
14,382
19,514
11,232
12,313
3,206
6,914
1,502
147
1,657
2,976
12,695
2,520
115
2025/07
580
203
513
48
27,644
60,349,070
4,308
688,623
377
10,957
359
14,376
19,508
11,232
12,304
3,202
6,914
1,502
147
1,648
2,932
12,668
2,514
114
2025/04
578
204
502
48
27,490
58,752,220
4,248
688,623
377
10,747
359
14,377
19,460
11,232
12,242
3,202
6,876
1,448
145
1,535
2,894
12,624
2,498
113
2025/01
576
204
496
48
27,323
57,059,025
4,231
688,632
377
10,505
359
14,377
19,435
11,232
12,199
3,202
6,876
1,445
144
1,527
2,832
12,559
2,491
112
2024/10
574
202
489
48
27,204
55,345,083
4,223
688,632
377
10,277
359
14,381
19,406
11,232
12,154
3,201
6,843
1,409
141
1,462
2,806
12,496
2,484
111
2024/07
572
201
482
48
26,831
54,120,639
4,196
688,823
377
10,044
359
14,384
19,367
11,220
12,102
3,197
6,800
1,408
141
1,452
2,762
12,456
2,473
110
2024/04
570
195
481
48
26,695
52,533,472
4,159
688,823
377
9,795
359
14,384
19,296
11,222
12,016
3,194
6,757
1,396
140
1,328
2,701
12,368
2,462
109
2024/01
568
193
479
48
26,435
50,464,740
4,167
688,823
377
9,591
359
14,387
19,270
11,219
11,990
3,194
6,728
1,405
139
1,274
2,676
12,286
2,449
108
2023/10
566
192
479
48
26,248
49,548,471
4,167
688,927
377
9,351
359
14,389
19,136
11,222
11,965
3,194
6,908
1,373
141
1,212
2,653
12,230
2,436
107
2023/07
564
186
478
46
25,918
47,311,190
4,162
660,913
372
9,105
359
12,950
19,119
11,222
11,941
3,195
6,890
1,308
156
1,096
2,644
12,163
2,432
106
2023/04
563
193
473
46
25,696
46,308,188
4,143
597,029
372
8,873
359
11,517
19,092
11,199
11,914
3,195
6,890
1,349
151
928
2,627
12,101
2,426
105
2023/01
562
190
473
46
25,563
44,620,638
4,125
596,851
312
8,649
359
11,512
19,048
11,117
11,862
3,194
6,852
1,328
146
871
2,619
12,028
2,413
104
2022/10
558
188
459
46
25,419
43,098,110
4,120
595,443
288
8,420
359
11,487
18,991
11,088
11,817
3,180
6,852
1,317
141
709
2,595
11,970
2,404
103
2022/07
551
185
459
46
25,221
41,718,457
4,106
595,312
256
8,194
359
11,487
18,920
11,084
11,775
3,177
6,811
1,241
134
458
2,567
11,918
2,395
102
2022/04
551
180
457
46
24,947
40,361,183
4,102
583,397
250
7,966
355
18,907
11,084
11,748
3,177
6,792
1,408
133
456
2,551
11,873
2,384
101
2022/01
548
180
456
46
24,839
38,588,545
4,090
582,137
250
7,723
355
18,871
11,068
11,666
3,180
6,761
1,408
133
456
2,537
11,802
2,372
100
2021/10
545
185
453
44
24,620
37,128,463
4,059
581,771
250
7,495
355
18,844
11,039
11,605
3,175
6,761
1,408
133
455
2,507
11,735
2,382
99
2021/07
547
184
446
44
24,465
34,367,988
4,048
529,308
118
7,254
355
18,815
11,039
11,558
3,170
6,725
1,378
130
455
2,507
11,664
2,325
98
2021/04
544
188
443
44
24,210
33,333,861
4,055
510,572
7,086
349
18,781
11,026
11,503
3,168
6,689
1,312
128
441
2,498
11,448
2,318
97
2021/01
541
187
443
44
23,923
32,706,068
4,041
479,672
6,927
349
18,749
11,042
11,467
3,168
6,670
1,315
127
441
2,463
11,378
2,309
96
2020/10
538
200
416
41
23,568
32,139,330
4,039
479,369
6,782
349
18,745
11,042
11,466
3,168
6,671
1,275
123
441
2,440
11,332
2,288
95
2020/07
537
200
409
41
23,424
31,519,703
4,007
372,704
6,626
341
18,720
11,040
11,438
3,169
6,636
1,060
118
423
2,424
11,274
2,278
94
2020/04
537
202
394
41
23,290
30,882,181
4,553
372,625
6,461
341
18,689
11,039
11,395
3,165
6,638
1,011
114
415
2,402
11,240
2,274
93
2020/01
537
202
394
41
23,187
30,302,142
4,505
372,564
6,305
340
18,653
11,041
11,336
3,164
6,585
944
100
395
2,371
11,144
2,249
92
2019/10
536
201
394
41
23,085
29,664,404
4,451
369,323
6,149
338
18,634
11,040
11,316
3,161
6,550
891
96
376
2,331
11,090
2,236
91
2019/07
535
201
406
22,853
29,249,229
4,439
362,957
5,994
338
18,553
11,040
11,213
3,153
6,479
782
91
307
2,316
11,022
2,219
90
2019/04
530
202
813
22,639
28,499,188
4,414
322,572
5,862
328
18,505
11,041
11,146
3,154
6,438
690
88
245
2,298
10,955
2,206
89
2019/01
530
202
811
22,456
27,389,826
4,386
322,572
5,718
328
18,464
11,040
11,092
3,150
6,410
515
67
171
2,260
10,804
2,177
88
2018/10
530
203
801
22,290
27,017,509
4,350
318,764
5,615
328
18,384
11,040
11,012
3,147
6,356
448
169
2,197
10,548
2,116
87
2018/07
527
202
793
22,170
26,278,914
4,344
314,990
5,480
317
18,342
11,032
10,937
3,112
6,320
438
169
2,121
10,518
2,077
86
2018/04
525
202
790
21,915
25,750,177
4,294
314,976
5,344
317
18,260
11,015
10,827
3,107
6,264
296
135
2,036
10,506
2,052
85
2018/01
521
239
788
21,712
24,911,585
4,266
313,051
5,213
317
18,221
11,015
10,788
3,109
6,233
282
118
2,007
10,484
2,715
84
2017/10
519
237
788
21,549
23,872,029
3,966
314,030
5,064
317
18,111
11,015
10,667
3,109
6,146
1,910
10,436
2,426
83
2017/07
517
236
783
21,188
22,439,071
3,943
311,760
4,900
317
18,048
11,015
10,584
3,115
6,108
1,854
10,340
2,119
82
2017/04
512
236
779
20,775
21,521,039
3,904
307,065
4,748
317
17,947
11,015
10,490
3,116
6,046
1,773
10,440
2,000
81
2017/01
502
234
765
20,420
20,696,825
3,780
273,878
4,567
317
17,848
11,015
10,362
3,080
5,998
1,704
10,441
1,958
80
2016/10
496
231
764
20,140
19,945,011
3,649
272,794
4,447
317
17,752
10,994
10,252
3,059
5,961
1,662
10,364
1,923
79
2016/07
490
232
757
19,717
19,007,402
3,451
271,866
4,290
120
17,689
10,989
10,183
3,044
5,907
1,557
10,352
1,891
78
2016/04
484
228
737
19,353
18,414,720
3,081
266,445
4,160
17,599
10,989
10,072
3,014
5,858
1,477
10,338
1,893
77
2016/01
482
222
719
19,116
17,653,626
2,630
228,477
4,061
17,535
10,989
9,983
2,990
5,856
1,445
10,319
1,879
76
2015/10
482
157
708
18,969
17,472,367
2,218
228,477
4,039
17,458
10,989
9,930
2,980
5,733
1,431
10,305
75
2015/07
478
157
707
18,812
17,132,869
218,147
3,936
17,421
10,989
9,889
2,970
5,733
1,423
10,170
74
2015/04
475
161
685
18,551
16,102,159
210,576
3,712
17,402
10,987
9,862
2,968
5,710
1,412
10,146
73
2015/01
470
158
652
18,334
15,346,261
3,495
17,343
10,987
9,775
2,945
5,671
1,402
10,130
72
2014/10
467
157
630
18,085
14,273,877
3,297
17,304
10,987
9,722
2,931
5,632
1,399
10,093
71
2014/07
464
148
618
17,874
13,149,919
3,091
17,269
10,985
9,679
2,917
5,577
1,396
10,086
70
2014/04
460
146
592
17,661
12,472,984
2,979
17,187
10,985
9,545
2,879
5,486
1,359
10,084
69
2014/01
457
145
590
17,383
12,216,183
2,968
17,148
10,985
9,484
2,858
5,440
1,301
10,074
68
2013/10
449
148
580
17,045
11,509,872
2,849
17,095
10,985
9,404
2,831
5,396
1,301
10,031
67
2013/07
442
143
572
16,765
10,909,953
2,702
17,024
10,985
9,338
2,811
5,328
1,301
9,922
66
2013/04
437
138
561
16,481
10,211,206
2,520
16,967
10,982
9,245
2,788
5,218
1,301
9,814
65
2013/01
432
141
558
16,238
9,794,752
2,390
16,913
10,980
9,174
2,767
5,147
1,301
9,816
64
2012/10
428
140
547
15,950
9,113,391
2,245
16,845
10,979
9,107
2,748
4,989
1,298
9,791
63
2012/07
425
139
536
15,728
8,837,513
2,151
16,789
10,979
9,028
2,605
1,231
9,779
62
2012/04
418
137
524
15,552
7,674,147
1,764
16,565
10,979
8,888
2,449
4,853
1,122
9,775
61
2012/01
414
135
434
15,400
7,176,414
1,646
16,316
10,979
8,841
2,458
4,785
778
9,748
60
2011/10
409
132
421
15,200
7,107,929
1,627
16,238
10,978
8,764
2,431
4,706
486
9,607
59
2011/07
398
126
371
14,857
6,759,505
1,555
17,639
10,978
8,496
12,649
375
9,407
58
2011/04
389
14,387
6,375,680
1,446
17,122
10,978
8,453
12,540
57
2011/01
379
14,069
6,104,532
1,373
16,401
10,973
8,373
12,462
56
2010/10
373
13,820
5,818,226
1,313
16,291
10,969
8,244
12,287
55
2010/07
363
13,660
5,659,677
1,263
16,255
10,969
8,177
12,265
54
2010/04
351
13,369
5,422,765
1,196
16,160
10,969
8,130
12,188
53
2010/01
344
12,877
5,195,943
1,141
16,091
10,969
8,076
12,032
52
2009/10
336
12,520
4,854,460
1,077
15,954
10,969
8,024
11,745
51
2009/07
331
12,259
4,604,914
1,011
15,686
10,969
7,936
11,364
8,912
50
2009/04
336
11,760
4,229,488
943
15,400
10,966
7,829
11,272
8,872
49
2009/01
344
11,417
4,214,060
882
15,309
10,966
7,816
11,032
7,871
48
2008/10
344
11,208
4,010,399
840
15,220
10,966
7,781
10,124
7,844
47
2008/07
341
10,958
3,321,599
776
15,188
10,966
7,654
9,537
7,059
46
2008/04
331
10,763
3,019,823
717
15,051
10,973
7,520
7,349
6,850
45
2008/01
323
10,686
2,846,561
673
14,980
10,972
7,417
7,334
6,637
44
2007/10
317
10,325
2,669,491
634
14,892
10,972
7,269
7,334
6,637
43
2007/07
307
10,016
2,396,769
574
14,738
10,959
7,054
7,192
5,933
42
2007/04
300
9,770
2,038,004
513
14,427
10,951
6,871
7,022
4,571
41
2007/01
294
9,286
1,871,732
465
14,258
10,951
6,811
7,089
4,152
40
2006/10
289
8,942
1,646,611
415
14,229
10,951
6,811
5,162
4,087
39
2006/07
275
8,553
1,549,332
388
14,126
10,949
6,682
5,162
3,439
38
2006/04
260
8,254
1,408,931
354
37
2006/01
240
7,983
1,254,322
327
36
2005/10
167
7,499
1,133,099
291
35
2005/07
166
6,674
940,517
254
34
2005/04
165
6,220
911,578
222
33
2005/01
164
5,841
866,039
210
32
2004/10
160
5,540
772,389
206
31
2004/07
153
4,715
713,034
193
30
2004/04
146
4,425
659,611
179
29
2004/01
151
3,976
597,435
174
10,788
10,146
5,902
28
2003/10
151
3,828
580,843
163
10,747
10,547
5,834
27
2003/07
151
3,627
526,464
145
10,746
10,448
5,739
26
2003/04
150
3,444
486,190
133
10,636
5,429
25
2003/01
149
3,371
417,535
118
10,519
5,399
24
2002/10
149
3,115
358,597
101
23
2002/07
148
343,860
95
22
2002/04
151
340,353
82
21
2002/01
146
328,344
79
20
2001/10
144
248,705
60
7,298
5,166
19
2001/07
223,104
53
18
2001/04
203,246
45
17
2001/01
174,226
39
16
2000/10
157,339
34
15
2000/07
138,518
31
14
2000/04
129,057
30
13
2000/01
114,553
25
12
1999/10
110,586
5,673
11
1999/07
93,445
10
1999/04
97,480
9
1999/01
78,337
8
1998/10
76,891
5,586
7
1998/07
65,592
5,432
6
1998/04
5
1998/01
4
1997/10
3
1997/07
2
1997/04
5,002
1
1996/10
4,940
0.1
1995/12