- Home
- Bioconductor 3.22
- Software Packages
- sincell
sincell
This is the released version of sincell; for the devel version, see sincell.
R package for the statistical assessment of cell state hierarchies from single-cell RNA-seq data
Bioconductor version: Release (3.22)
Cell differentiation processes are achieved through a continuum of hierarchical intermediate cell-states that might be captured by single-cell RNA seq. Existing computational approaches for the assessment of cell-state hierarchies from single-cell data might be formalized under a general workflow composed of i) a metric to assess cell-to-cell similarities (combined or not with a dimensionality reduction step), and ii) a graph-building algorithm (optionally making use of a cells-clustering step). Sincell R package implements a methodological toolbox allowing flexible workflows under such framework. Furthermore, Sincell contributes new algorithms to provide cell-state hierarchies with statistical support while accounting for stochastic factors in single-cell RNA seq. Graphical representations and functional association tests are provided to interpret hierarchies.
Author: Miguel Julia <migueljuliamolina at gmail.com>, Amalio Telenti <atelenti at jcvi.org>, Antonio Rausell <antonio.rausell at institutimagine.org>
Maintainer: Miguel Julia <migueljuliamolina at gmail.com>, Antonio Rausell<antonio.rausell at institutimagine.org>
citation("sincell")):
Installation
To install this package, start R (version "4.5") and enter:
if (!require("BiocManager", quietly = TRUE))
install.packages("BiocManager")
BiocManager::install("sincell")
For older versions of R, please refer to the appropriate Bioconductor release.
Documentation
To view documentation for the version of this package installed in your system, start R and enter:
browseVignettes("sincell")
Details
See More
Package Archives
Follow Installation instructions to use this package in your R session.