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nipalsMCIA

This is the released version of nipalsMCIA; for the devel version, see nipalsMCIA.

Multiple Co-Inertia Analysis via the NIPALS Method


Bioconductor version: Release (3.22)

Computes Multiple Co-Inertia Analysis (MCIA), a dimensionality reduction (jDR) algorithm, for a multi-block dataset using a modification to the Nonlinear Iterative Partial Least Squares method (NIPALS) proposed in (Hanafi et. al, 2010). Allows multiple options for row- and table-level preprocessing, and speeds up computation of variance explained. Vignettes detail application to bulk- and single cell- multi-omics studies.

Author: Maximilian Mattessich [cre] ORCID iD ORCID: 0000-0002-1233-1240 , Joaquin Reyna [aut] ORCID iD ORCID: 0000-0002-8468-2840 , Edel Aron [aut] ORCID iD ORCID: 0000-0002-8683-4772 , Ferhat Ay [aut] ORCID iD ORCID: 0000-0002-0708-6914 , Steven Kleinstein [aut] ORCID iD ORCID: 0000-0003-4957-1544 , Anna Konstorum [aut] ORCID iD ORCID: 0000-0003-4024-2058

Maintainer: Maximilian Mattessich <maximilian.mattessich at northwestern.edu>

Citation (from within R, enter citation("nipalsMCIA")):

Installation

To install this package, start R (version "4.5") and enter:


if (!require("BiocManager", quietly = TRUE))
 install.packages("BiocManager")
BiocManager::install("nipalsMCIA")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("nipalsMCIA")
Analysis of MCIA Decomposition HTML R Script
Predicting New MCIA scores HTML R Script
Single Cell Analysis HTML R Script
Reference Manual PDF
NEWS Text

Details

Version 1.8.0
In Bioconductor since BioC 3.18 (R-4.3) (2 years)
License GPL-3
Depends R (>= 4.3.0)
Imports ComplexHeatmap, dplyr, fgsea, ggplot2 (>= 3.0.0), graphics, grid, methods, MultiAssayExperiment, SummarizedExperiment, pracma, rlang, RSpectra, scales, stats
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Package Archives

Follow Installation instructions to use this package in your R session.

Source Package nipalsMCIA_1.8.0.tar.gz
Windows Binary (x86_64) nipalsMCIA_1.7.0.zip
macOS Binary (x86_64) nipalsMCIA_1.8.0.tgz
macOS Binary (arm64) nipalsMCIA_1.8.0.tgz
Source Repository git clone https://git.bioconductor.org/packages/nipalsMCIA
Source Repository (Developer Access) git clone git@git.bioconductor.org:packages/nipalsMCIA
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