SimBu
This is the released version of SimBu; for the devel version, see SimBu.
Simulate Bulk RNA-seq Datasets from Single-Cell Datasets
Bioconductor version: Release (3.22)
SimBu can be used to simulate bulk RNA-seq datasets with known cell type fractions. You can either use your own single-cell study for the simulation or the sfaira database. Different pre-defined simulation scenarios exist, as are options to run custom simulations. Additionally, expression values can be adapted by adding an mRNA bias, which produces more biologically relevant simulations.
Author: Alexander Dietrich [aut, cre]
Maintainer: Alexander Dietrich <alex.dietrich at tum.de>
citation("SimBu")):
Installation
To install this package, start R (version "4.5") and enter:
if (!require("BiocManager", quietly = TRUE))
install.packages("BiocManager")
BiocManager::install("SimBu")
For older versions of R, please refer to the appropriate Bioconductor release.
Documentation
To view documentation for the version of this package installed in your system, start R and enter:
browseVignettes("SimBu")
Details
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Package Archives
Follow Installation instructions to use this package in your R session.