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EpiCompare

This is the released version of EpiCompare; for the devel version, see EpiCompare.

Comparison, Benchmarking & QC of Epigenomic Datasets


Bioconductor version: Release (3.22)

EpiCompare is used to compare and analyse epigenetic datasets for quality control and benchmarking purposes. The package outputs an HTML report consisting of three sections: (1. General metrics) Metrics on peaks (percentage of blacklisted and non-standard peaks, and peak widths) and fragments (duplication rate) of samples, (2. Peak overlap) Percentage and statistical significance of overlapping and non-overlapping peaks. Also includes upset plot and (3. Functional annotation) functional annotation (ChromHMM, ChIPseeker and enrichment analysis) of peaks. Also includes peak enrichment around TSS.

Author: Sera Choi [aut] ORCID iD ORCID: 0000-0002-5077-1984 , Brian Schilder [aut] ORCID iD ORCID: 0000-0001-5949-2191 , Leyla Abbasova [aut], Alan Murphy [aut] ORCID iD ORCID: 0000-0002-2487-8753 , Nathan Skene [aut] ORCID iD ORCID: 0000-0002-6807-3180 , Thomas Roberts [ctb], Hiranyamaya Dash [cre] ORCID iD ORCID: 0009-0005-5514-505X

Maintainer: Hiranyamaya Dash <hdash.work at gmail.com>

Citation (from within R, enter citation("EpiCompare")):

Installation

To install this package, start R (version "4.5") and enter:


if (!require("BiocManager", quietly = TRUE))
 install.packages("BiocManager")
BiocManager::install("EpiCompare")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("EpiCompare")
docker HTML R Script
EpiCompare HTML R Script
example_report HTML R Script
Reference Manual PDF
NEWS Text

Details

Version 1.14.0
In Bioconductor since BioC 3.15 (R-4.2) (3.5 years)
License GPL-3
Depends R (>= 4.2.0)
Imports AnnotationHub, ChIPseeker, data.table, genomation, GenomicRanges, IRanges(>= 2.41.3), Seqinfo(>= 0.99.2), GenomeInfoDb(>= 1.45.7), ggplot2 (>= 3.5.0), htmltools, methods, plotly, reshape2, rmarkdown, rtracklayer, stats, stringr, utils, BiocGenerics, downloadthis, parallel
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Package Archives

Follow Installation instructions to use this package in your R session.

Source Package EpiCompare_1.14.0.tar.gz
Windows Binary (x86_64) EpiCompare_1.13.1.zip (64-bit only)
macOS Binary (x86_64) EpiCompare_1.14.0.tgz
macOS Binary (arm64) EpiCompare_1.14.0.tgz
Source Repository git clone https://git.bioconductor.org/packages/EpiCompare
Source Repository (Developer Access) git clone git@git.bioconductor.org:packages/EpiCompare
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