Reactome Pathway Database

Schema > BlackBoxEvent > Entries

AFG3L2 degrades mitochondrial matrix proteins Show undefined attributes

catalystActivity

[CatalystActivity:10674138] ATP-dependent peptidase activity of AFG3L2:substrate protein (mitochondrial matrix) [mitochondrial inner membrane]

category omitted

compartment

[Compartment:70616] mitochondrial inner membrane

created [InstanceEdit:10603480] Weiser, Joel, 2025年08月27日

dbId 10674140

displayName AFG3L2 degrades mitochondrial matrix proteins

eventOf

[Pathway:R-XTR-9837999] Mitochondrial protein degradation - Xenopus tropicalis

evidenceType [EvidenceType:9965817] inferred by electronic annotation

inferredFrom

[BlackBoxEvent:R-HSA-9839105] AFG3L2 degrades mitochondrial matrix proteins - Homo sapiens

input

isInDisease false

isInferred true

maxDepth 1

name

AFG3L2 degrades mitochondrial matrix proteins

output

precedingEvent

[Reaction:R-XTR-9839149] AFG3L2 binds mitochondrial matrix proteins - Xenopus tropicalis

releaseDate 2025年09月18日

schemaClass BlackBoxEvent

species

[Species:205621] Xenopus tropicalis

stId R-XTR-9839105

summation

[Summation:9965816] This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)

[Pathway:R-XTR-9837999] Mitochondrial protein degradation

(inferredTo)

[BlackBoxEvent:R-HSA-9839105] AFG3L2 degrades mitochondrial matrix proteins

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