Reactome Pathway Database

Schema > Reaction > Entries

ADA catalyzes the deamination of (deoxy)adenosine Show undefined attributes

catalystActivity

[CatalystActivity:10607119] deaminase activity of ADA [cytosol]

category transition

compartment

[Compartment:70101] cytosol

created [InstanceEdit:10603480] Weiser, Joel, 2025年08月27日

dbId 10607121

displayName ADA catalyzes the deamination of (deoxy)adenosine

eventOf

[Pathway:R-XTR-74217] Purine salvage - Xenopus tropicalis

evidenceType [EvidenceType:9965817] inferred by electronic annotation

followingEvent

[Reaction:R-XTR-74242] PNP catalyzes the conversion of (deoxy)inosine to hypoxanthine and (deoxy)ribose - Xenopus tropicalis

inferredFrom

[Reaction:R-HSA-74241] ADA catalyzes the deamination of (deoxy)adenosine - Homo sapiens

input

isInDisease false

isInferred true

maxDepth 1

name

ADA catalyzes the deamination of (deoxy)adenosine
(2'-deoxy)adenosine + H2O => (2'-deoxy)inosine + NH4+ (ADA)

output

releaseDate 2025年09月18日

schemaClass Reaction

species

[Species:205621] Xenopus tropicalis

stId R-XTR-74241

summation

[Summation:9965816] This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)

[Pathway:R-XTR-74217] Purine salvage

(precedingEvent)

[Reaction:R-XTR-74242] PNP catalyzes the conversion of (deoxy)inosine to hypoxanthine and (deoxy)ribose

(inferredTo)

[Reaction:R-HSA-74241] ADA catalyzes the deamination of (deoxy)adenosine

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