Reactome Pathway Database

Schema > Reaction > Entries

PPP1CC dephosphorylates PLK1 Show undefined attributes

catalystActivity

[CatalystActivity:10534623] protein serine/threonine phosphatase activity of PPP1CC [cytosol]

category transition

compartment

[Compartment:70101] cytosol

created [InstanceEdit:10424722] Weiser, Joel, 2025年08月27日

dbId 10534625

displayName PPP1CC dephosphorylates PLK1

eventOf

[Pathway:R-SSC-2500257] Resolution of Sister Chromatid Cohesion - Sus scrofa

evidenceType [EvidenceType:9965817] inferred by electronic annotation

inferredFrom

[Reaction:R-HSA-9853385] PPP1CC dephosphorylates PLK1 - Homo sapiens

input

isInDisease false

isInferred true

maxDepth 1

name

PPP1CC dephosphorylates PLK1

output

regulatedBy

[NegativeRegulation:10534626] Negative regulation by 'FIRRM:PPP1CC [cytosol]'

releaseDate 2025年09月18日

schemaClass Reaction

species

[Species:49633] Sus scrofa

stId R-SSC-9853385

summation

[Summation:9965816] This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)

[Pathway:R-SSC-2500257] Resolution of Sister Chromatid Cohesion

(inferredTo)

[Reaction:R-HSA-9853385] PPP1CC dephosphorylates PLK1

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