Reactome Pathway Database

Schema > Reaction > Entries

AFG3L2 binds mitochondrial matrix proteins Show undefined attributes

category binding

compartment

created [InstanceEdit:10424722] Weiser, Joel, 2025年08月27日

dbId 10533803

displayName AFG3L2 binds mitochondrial matrix proteins

eventOf

[Pathway:R-SSC-9837999] Mitochondrial protein degradation - Sus scrofa

evidenceType [EvidenceType:9965817] inferred by electronic annotation

followingEvent

[BlackBoxEvent:R-SSC-9839105] AFG3L2 degrades mitochondrial matrix proteins - Sus scrofa

inferredFrom

[Reaction:R-HSA-9839149] AFG3L2 binds mitochondrial matrix proteins - Homo sapiens

input

isInDisease false

isInferred true

maxDepth 1

name

AFG3L2 binds mitochondrial matrix proteins

output

[Complex:R-SSC-9839083] AFG3L2:substrate protein (mitochondrial matrix) [mitochondrial inner membrane]

releaseDate 2025年09月18日

schemaClass Reaction

species

[Species:49633] Sus scrofa

stId R-SSC-9839149

summation

[Summation:9965816] This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)

[Pathway:R-SSC-9837999] Mitochondrial protein degradation

(precedingEvent)

[BlackBoxEvent:R-SSC-9839105] AFG3L2 degrades mitochondrial matrix proteins

(inferredTo)

[Reaction:R-HSA-9839149] AFG3L2 binds mitochondrial matrix proteins

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