Reactome Pathway Database

Schema > Reaction > Entries

PRPS dimers pyrophosphorylate R5P using ATP Show undefined attributes

catalystActivity

[CatalystActivity:10428745] ribose phosphate diphosphokinase activity of PRPS dimers [cytosol]

category transition

compartment

[Compartment:70101] cytosol

created [InstanceEdit:10424722] Weiser, Joel, 2025年08月27日

dbId 10428747

displayName PRPS dimers pyrophosphorylate R5P using ATP

eventOf

[Pathway:R-SSC-73843] 5-Phosphoribose 1-diphosphate biosynthesis - Sus scrofa

evidenceType [EvidenceType:9965817] inferred by electronic annotation

followingEvent

inferredFrom

[Reaction:R-HSA-73580] PRPS dimers pyrophosphorylate R5P using ATP - Homo sapiens

input

isInDisease false

isInferred true

maxDepth 1

name

PRPS dimers pyrophosphorylate R5P using ATP
D-ribose 5-phosphate + ATP => 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + adenosine 5'-monophosphate
addition of diphosphate (PP) to ribose 5-phosphate to form 5'-Phospho-alpha-D-ribose 1-diphosphate (PRPP)

output

precedingEvent

[Reaction:R-SSC-71306] RPIA isomerizes D-ribulose 5-phosphate to ribose 5-phosphate - Sus scrofa

regulatedBy

releaseDate 2025年09月18日

schemaClass Reaction

species

[Species:49633] Sus scrofa

stId R-SSC-73580

summation

[Summation:9965816] This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(precedingEvent)

(hasEvent)

[Pathway:R-SSC-73843] 5-Phosphoribose 1-diphosphate biosynthesis

(inferredTo)

[Reaction:R-HSA-73580] PRPS dimers pyrophosphorylate R5P using ATP

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