Reactome Pathway Database

Schema > Reaction > Entries

PPA1 hydrolyzes pyrophosphate to orthophosphate Show undefined attributes

catalystActivity

[CatalystActivity:10427529] inorganic diphosphate phosphatase activity of PPA1 dimer [cytosol]

category transition

compartment

[Compartment:70101] cytosol

created [InstanceEdit:10424722] Weiser, Joel, 2025年08月27日

dbId 10427531

displayName PPA1 hydrolyzes pyrophosphate to orthophosphate

eventOf

evidenceType [EvidenceType:9965817] inferred by electronic annotation

inferredFrom

[Reaction:R-HSA-71732] PPA1 hydrolyzes pyrophosphate to orthophosphate - Homo sapiens

input

isInDisease false

isInferred true

maxDepth 1

name

PPA1 hydrolyzes pyrophosphate to orthophosphate
pyrophosphate + H2O => 2 orthophosphate [cytosolic]

output

2 × [SimpleEntity:R-ALL-29372] Pi [cytosol]

precedingEvent

regulatedBy

[Requirement:R-HSA-2509853] Requirement by 'Mg2+ [cytosol]'

releaseDate 2025年09月18日

schemaClass Reaction

species

[Species:49633] Sus scrofa

stId R-SSC-71732

summation

[Summation:9965816] This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)

(inferredTo)

[Reaction:R-HSA-71732] PPA1 hydrolyzes pyrophosphate to orthophosphate

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