Reactome Pathway Database

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Synthesis of diphthamide-EEF2 Show undefined attributes

compartment

[Compartment:70101] cytosol

created [InstanceEdit:10424722] Weiser, Joel, 2025年08月27日

dbId 10539929

displayName Synthesis of diphthamide-EEF2

eventOf

[Pathway:R-SSC-163841] Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation - Sus scrofa

evidenceType [EvidenceType:9965817] inferred by electronic annotation

goBiologicalProcess [GO_BiologicalProcess:25723] protein histidyl modification to diphthamide

hasDiagram false

hasEHLD false

hasEvent

inferredFrom

[Pathway:R-HSA-5358493] Synthesis of diphthamide-EEF2 - Homo sapiens

isInDisease false

isInferred true

maxDepth 2

name

Synthesis of diphthamide-EEF2

releaseDate 2025年09月18日

schemaClass Pathway

species

[Species:49633] Sus scrofa

stId R-SSC-5358493

summation

[Summation:9965816] This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)

[Pathway:R-SSC-163841] Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation

(inferredTo)

[Pathway:R-HSA-5358493] Synthesis of diphthamide-EEF2

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