Reactome Pathway Database

Schema > Reaction > Entries

BORA binds PLK1 and AURKA Show undefined attributes

category binding

compartment

[Compartment:70101] cytosol

created [InstanceEdit:10424722] Weiser, Joel, 2025年08月27日

dbId 10486641

displayName BORA binds PLK1 and AURKA

eventOf

[Pathway:R-SSC-2565942] Regulation of PLK1 Activity at G2/M Transition - Sus scrofa

evidenceType [EvidenceType:9965817] inferred by electronic annotation

followingEvent

[Reaction:R-SSC-3000310] AURKA phosphorylates PLK1 - Sus scrofa

inferredFrom

[Reaction:R-HSA-3000319] BORA binds PLK1 and AURKA - Homo sapiens

input

isInDisease false

isInferred true

maxDepth 1

name

BORA binds PLK1 and AURKA

output

[Complex:R-SSC-3000313] Centrosome:p-T288-AURKA:p-S252-BORA:PLK1 [cytosol]

precedingEvent

releaseDate 2025年09月18日

schemaClass Reaction

species

[Species:49633] Sus scrofa

stId R-SSC-3000319

summation

[Summation:9965816] This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)

[Pathway:R-SSC-2565942] Regulation of PLK1 Activity at G2/M Transition

(precedingEvent)

[Reaction:R-SSC-3000310] AURKA phosphorylates PLK1

(inferredTo)

[Reaction:R-HSA-3000319] BORA binds PLK1 and AURKA

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