Reactome Pathway Database

Schema > BlackBoxEvent > Entries

Degradation of multiubiquitinated cell cycle proteins Show undefined attributes

catalystActivity

[CatalystActivity:10425485] endopeptidase activity of 26S proteasome [cytosol]

category omitted

compartment

[Compartment:70101] cytosol

created [InstanceEdit:10424722] Weiser, Joel, 2025年08月27日

dbId 10439073

displayName Degradation of multiubiquitinated cell cycle proteins

eventOf

[Pathway:R-SSC-174178] APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 - Sus scrofa

evidenceType [EvidenceType:9965817] inferred by electronic annotation

inferredFrom

[BlackBoxEvent:R-HSA-174105] Degradation of multiubiquitinated cell cycle proteins - Homo sapiens

input

[Complex:R-SSC-174248] multiubiquitinated cell cycle protein:APC/C:Cdh1 complex [cytosol]

isInDisease false

isInferred true

maxDepth 1

name

Degradation of multiubiquitinated cell cycle proteins

output

precedingEvent

[Reaction:R-SSC-174195] Ubiquitination of cell cycle proteins targeted by the APC/C:Cdh1complex - Sus scrofa

releaseDate 2025年09月18日

schemaClass BlackBoxEvent

species

[Species:49633] Sus scrofa

stId R-SSC-174105

summation

[Summation:9965816] This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)

[Pathway:R-SSC-174178] APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1

(inferredTo)

[BlackBoxEvent:R-HSA-174105] Degradation of multiubiquitinated cell cycle proteins

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