Reactome Pathway Database

Schema > Reaction > Entries

SLC25A5,6 dimers exchange ATP for ADP across the mitochondrial inner membrane Show undefined attributes

catalystActivity

[CatalystActivity:10436145] adenine transmembrane transporter activity of SLC25A5,6 dimers [mitochondrial inner membrane]

category transition

compartment

[Compartment:70616] mitochondrial inner membrane

created [InstanceEdit:10424722] Weiser, Joel, 2025年08月27日

dbId 10436147

displayName SLC25A5,6 dimers exchange ATP for ADP across the mitochondrial inner membrane

eventOf

[Pathway:R-SSC-83936] Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane - Sus scrofa

evidenceType [EvidenceType:9965817] inferred by electronic annotation

followingEvent

[Reaction:R-SSC-164840] ADP and Pi bind to ATPase - Sus scrofa

inferredFrom

[Reaction:R-HSA-163215] SLC25A5,6 dimers exchange ATP for ADP across the mitochondrial inner membrane - Homo sapiens

input

isInDisease false

isInferred true

maxDepth 1

name

SLC25A5,6 dimers exchange ATP for ADP across the mitochondrial inner membrane
ADP-ATP translocase maintains a high ADP:ATP ratio in the matrix

output

precedingEvent

releaseDate 2025年09月18日

schemaClass Reaction

species

[Species:49633] Sus scrofa

stId R-SSC-163215

summation

[Summation:9965816] This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)

[Pathway:R-SSC-83936] Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane

(inferredTo)

[Reaction:R-HSA-163215] SLC25A5,6 dimers exchange ATP for ADP across the mitochondrial inner membrane

(precedingEvent)

[Reaction:R-SSC-164840] ADP and Pi bind to ATPase

© 2025 Reactome

Cite Us!