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Homocysteine is degraded to oxobutanoate and H2S Show undefined attributes

catalystActivity

[CatalystActivity:10474134] homocysteine desulfhydrase activity of PXLP-K212-CTH tetramer [cytosol]

category transition

compartment

[Compartment:70101] cytosol

created [InstanceEdit:10424722] Weiser, Joel, 2025年08月27日

dbId 10474136

displayName Homocysteine is degraded to oxobutanoate and H2S

eventOf

[Pathway:R-SSC-1614558] Degradation of cysteine and homocysteine - Sus scrofa

evidenceType [EvidenceType:9965817] inferred by electronic annotation

inferredFrom

[Reaction:R-HSA-1614631] Homocysteine is degraded to oxobutanoate and H2S - Homo sapiens

input

isInDisease false

isInferred true

maxDepth 1

name

Homocysteine is degraded to oxobutanoate and H2S
H2O + L-homocysteine => 2-oxobutanoate + H(+) + hydrogen sulfide + NH4(+)

output

precedingEvent

[Reaction:R-SSC-174401] AHCY:NAD+ tetramer hydrolyses AdoHcy - Sus scrofa

releaseDate 2025年09月18日

schemaClass Reaction

species

[Species:49633] Sus scrofa

stId R-SSC-1614631

summation

[Summation:9965816] This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)

[Pathway:R-SSC-1614558] Degradation of cysteine and homocysteine

(inferredTo)

[Reaction:R-HSA-1614631] Homocysteine is degraded to oxobutanoate and H2S

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