Reactome Pathway Database

Schema > Reaction > Entries

PXLP-CBS tetramers condenses HCYS and L-Ser to form L-Cystathionine Show undefined attributes

catalystActivity

[CatalystActivity:10474087] cystathionine beta-synthase activity of PXLP-K119-CBS tetramer [cytosol]

category transition

compartment

[Compartment:70101] cytosol

created [InstanceEdit:10424722] Weiser, Joel, 2025年08月27日

dbId 10474089

displayName PXLP-CBS tetramers condenses HCYS and L-Ser to form L-Cystathionine

eventOf

[Pathway:R-SSC-1614603] Cysteine formation from homocysteine - Sus scrofa

evidenceType [EvidenceType:9965817] inferred by electronic annotation

followingEvent

[Reaction:R-SSC-1614583] PXLP-K212-CTH cleaves L-Cystathionine - Sus scrofa

inferredFrom

[Reaction:R-HSA-1614524] PXLP-CBS tetramers condenses HCYS and L-Ser to form L-Cystathionine - Homo sapiens

input

isInDisease false

isInferred true

maxDepth 1

name

PXLP-CBS tetramers condenses HCYS and L-Ser to form L-Cystathionine
L-homocysteine + L-serine => H2O + L,L-cystathionine

output

precedingEvent

[Reaction:R-SSC-174401] AHCY:NAD+ tetramer hydrolyses AdoHcy - Sus scrofa

releaseDate 2025年09月18日

schemaClass Reaction

species

[Species:49633] Sus scrofa

stId R-SSC-1614524

summation

[Summation:9965816] This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)

[Pathway:R-SSC-1614603] Cysteine formation from homocysteine

(precedingEvent)

[Reaction:R-SSC-1614583] PXLP-K212-CTH cleaves L-Cystathionine

(inferredTo)

[Reaction:R-HSA-1614524] PXLP-CBS tetramers condenses HCYS and L-Ser to form L-Cystathionine

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