Reactome Pathway Database

Schema > Reaction > Entries

1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/2 in the nucleus Show undefined attributes

catalystActivity

[CatalystActivity:11014297] diphosphoinositol pentakisphosphate kinase activity of IP6K1/2 [nucleoplasm]

category transition

compartment

[Compartment:7660] nucleoplasm

created [InstanceEdit:11001822] Weiser, Joel, 2025年08月28日

dbId 11014299

displayName 1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/2 in the nucleus

eventOf

[Pathway:R-SPO-1855191] Synthesis of IPs in the nucleus - Schizosaccharomyces pombe

evidenceType [EvidenceType:9965817] inferred by electronic annotation

followingEvent

[Reaction:R-SPO-1855220] (PP)2-IP4 transports from the nucleus to the cytosol - Schizosaccharomyces pombe

inferredFrom

[Reaction:R-HSA-1855157] 1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/2 in the nucleus - Homo sapiens

input

isInDisease false

isInferred true

maxDepth 1

name

1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/2 in the nucleus

output

precedingEvent

[Reaction:R-SPO-1855212] 1/3-PP-IP5 transports from the cytosol to the nucleus - Schizosaccharomyces pombe

releaseDate 2025年09月18日

schemaClass Reaction

species

[Species:68324] Schizosaccharomyces pombe

stId R-SPO-1855157

summation

[Summation:9965816] This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)

[Pathway:R-SPO-1855191] Synthesis of IPs in the nucleus

(precedingEvent)

[Reaction:R-SPO-1855220] (PP)2-IP4 transports from the nucleus to the cytosol

(inferredTo)

[Reaction:R-HSA-1855157] 1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/2 in the nucleus

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