Reactome Pathway Database

Schema > Reaction > Entries

DGC complex binds AGRN and HSPG2 Show undefined attributes

category binding

compartment

created [InstanceEdit:10084857] Weiser, Joel, 2025年08月27日

dbId 10195466

displayName DGC complex binds AGRN and HSPG2

eventOf

[Pathway:R-RNO-9913351] Formation of the dystrophin-glycoprotein complex (DGC) - Rattus norvegicus

evidenceType [EvidenceType:9965817] inferred by electronic annotation

inferredFrom

[Reaction:R-HSA-9914537] DGC complex binds AGRN and HSPG2 - Homo sapiens

input

isInDisease false

isInferred true

maxDepth 1

name

DGC complex binds AGRN and HSPG2

output

[Complex:R-RNO-9914533] DGC complex:laminins:F-actin:AGRN,HSPG2 [plasma membrane]

releaseDate 2025年09月18日

schemaClass Reaction

species

[Species:48895] Rattus norvegicus

stId R-RNO-9914537

summation

[Summation:9965816] This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)

[Pathway:R-RNO-9913351] Formation of the dystrophin-glycoprotein complex (DGC)

(inferredTo)

[Reaction:R-HSA-9914537] DGC complex binds AGRN and HSPG2

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